ID F6RCH0_CALJA Unreviewed; 1982 AA.
AC F6RCH0;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 3.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=Myosin heavy chain 7B {ECO:0000313|Ensembl:ENSCJAP00000033213.4};
GN Name=MYH7B {ECO:0000313|Ensembl:ENSCJAP00000033213.4};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000033213.4, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000033213.4}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000033213.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR STRING; 9483.ENSCJAP00000033213; -.
DR Ensembl; ENSCJAT00000035099.4; ENSCJAP00000033213.4; ENSCJAG00000017977.4.
DR eggNOG; KOG0161; Eukaryota.
DR GeneTree; ENSGT00940000160950; -.
DR HOGENOM; CLU_000192_8_0_1; -.
DR InParanoid; F6RCH0; -.
DR OMA; CYLRQGY; -.
DR TreeFam; TF314375; -.
DR Proteomes; UP000008225; Chromosome 5.
DR Bgee; ENSCJAG00000017977; Expressed in heart and 6 other cell types or tissues.
DR GO; GO:0097512; C:cardiac myofibril; IEA:Ensembl.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0032982; C:myosin filament; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR CDD; cd14927; MYSc_Myh7b; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.340; -; 3.
DR Gene3D; 1.20.5.370; -; 4.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.30.360; Myosin S1 fragment, N-terminal; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR008989; Myosin_S1_N.
DR InterPro; IPR002928; Myosin_tail.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014751; XRCC4-like_C.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR PANTHER; PTHR45615:SF29; MYOSIN-7B; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF02736; Myosin_N; 1.
DR Pfam; PF01576; Myosin_tail_1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 6.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Muscle protein {ECO:0000256|ARBA:ARBA00023179};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW Thick filament {ECO:0000256|ARBA:ARBA00022433}.
FT DOMAIN 71..121
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 125..826
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 703..725
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 1945..1982
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 218..225
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1982 AA; 225642 MW; 1392AC184AD5F412 CRC64;
GGNKRGSTAS CPHRGAECLL PWATSNLQGF QLFLLHPSAT AMMDVSELGE SARYLRQGYQ
EMMKVHTIPW DGKKRVWVPD EQDAYVEAEV KSEATGGRVT VETKDQKVLT VREAELQPMN
PPRFDLLEDL AMMTHLNEAS VLHNLRQRYA RWMIYTYSGL FCVTINPYKW LPVYTASVVA
AYKGKRRSEA PPHIYSVADN AYNDMLRNRD NQSMLITGES GAGKTVNTKR VIQYFAIVAA
LGDGPGKKAQ FLATKTGGTL EDQIIEANPA MEAFGNAKTL RNDNSSRFGK FIRIHFGPSG
KLASADIDSY LLEKSRVIFQ LPGERGYHVY YQILSGKKPE LQDMLLLSMN PYDYHFCSQG
VITVDNMNDG EELIATDHAM DILGFSMDEK CACYKIVGAL LHFGNMKFKQ KQREEQAEAD
GTESADKAAY LMGVSSGDLL KGLLHPRVRV GNEYVTKGQS VEQVVFAVGA LAKATYDRLF
RWLVSRINQT LDTKLPRQFF IGVLDIAGFE IFEFNSFEQL CINFTNEKLQ QFFNQHMFVL
EQEEYKREGI DWVFIDFGLD LQPCIDLIEK PLGILSILEE ECMFPKASDA SFRAKLYDNH
AGKSPNFQQP RPDKKRKYQA HFEVVHYAGV VPYSIVGWLE KNKDPLNETV VPIFQKSQNR
LLATLYENYA GSCSTEPPKS GVKEKRKKAA SFQTVSQLHK ENLNKLMTNL RATQPHFVRC
IVPNENKTPG VMDAFLVLHQ LRCNGVLEGI RICRQGFPNR LLYTDFRQRY RILNPSAIPD
DTFMDSRKAT EKLLGSLDLD HTQYQLGHTK VFFKAGLLGV LEELRDQRLA KVLTLLQARS
RGRLMRLEYQ HLLGGRDALF TIQWNIRAFN AVKNWSWMKL FFKMKPLLRS AQAEEELAAL
RAELRGLRGA LAAAEAKRQE LEETHVSVTQ EKNDLALQLQ AEQDNLADAE ERCHLLIKSK
VQLEGKVKEL SERLEDEEEV NADLAARRRK LEDECTELKK DIDDLELTLA KAEKEKQATE
NKVKNLTEEM AALDESVARL TKEKKALQEA HQQALGDLQA EEDRVSALTK AKIRLEQQVE
DLECSLEQEK KLRMDTERAK RKLEGDLKLT QESVADAAQD KQQLEEQLKK KDSELSQLSL
RVEDEQLLGA QLQKKIKELQ ARAEELEEEL EAERAARARV EKQRAEAARE LEELSERLEE
AGGASAGQRE GCRKREAELG RLRRELEEAA LRHEATVAAL RRKQVEGAAE LGEQVDSLQR
VRQKLEKEKS ELRMEVDDLA ANVETLTRAK ASAEKLCRTH EDQLSEAKIK VEELQRQLAD
ASTQRGRLQT ESGELSRLLE EKECLISQLS RGKALAAQSL EELRRQLEEE SKAKNALAHA
VQALRHDCDL LREQHEEEAE AQAELQRLLS KANAEVAQWR SKYEADAIQR TEELEEAKKK
LALRLQEAEE GVEAANAKCS SLEKAKLRLQ TESEDVTLEL ERATSAAAAL DKKQRHLERA
LEERRRQEEE MQRELEAAQR EARGLGTELF RLRHSHEEAL EALETLKREN KNLQEEISDL
TDQVSLSGKT IQELEKAKKA LEGEKSEIQA ALEEAEGALE LEETKTLRIQ LELSQVKAEV
DRKLAEKDEE CTNLRRNHQR AVESLQASLD AETRARNEAL RLKKKMEGDL NDLELQLGHA
TRQATEAQAA TRLMQAQLKE EQAGRDEEQR LAAELREQAQ ALERRAALLA AELEELRAAL
EQGERSRRLA EQELLEATER LNLLHSQNTG LLNQKKKLEA DLAQLSGEVE EAAQERREAE
EKAKKAITDA AMMAEELKKE QDTSAHLERM KKTLEQTVRE LQARLEETEQ AALRGGKKQV
QKLEAKVREL EAELDAEQKK HAEALKGVRK HERRVKELAY QAEEDRKNLA RMQDLVDKLQ
SKVKSYKRQF EEAEQQANTN LAKYRKAQHE LDDAEERADM AETQANKLRA RTRDALGPKH
KE
//
