ID F6RG68_MOUSE Unreviewed; 356 AA.
AC F6RG68;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 3.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=FCH domain only 2 {ECO:0000313|Ensembl:ENSMUSP00000096883.6};
GN Name=Fcho2 {ECO:0000313|Ensembl:ENSMUSP00000096883.6,
GN ECO:0000313|MGI:MGI:3505790};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000096883.6, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000096883.6, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000096883.6,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000096883.6}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000096883.6};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F6RG68; -.
DR SMR; F6RG68; -.
DR PeptideAtlas; F6RG68; -.
DR ProteomicsDB; 359319; -.
DR Antibodypedia; 48744; 165 antibodies from 23 providers.
DR Ensembl; ENSMUST00000099277.12; ENSMUSP00000096883.6; ENSMUSG00000041685.17.
DR AGR; MGI:3505790; -.
DR MGI; MGI:3505790; Fcho2.
DR VEuPathDB; HostDB:ENSMUSG00000041685; -.
DR GeneTree; ENSGT00940000157105; -.
DR ChiTaRS; Fcho2; mouse.
DR Proteomes; UP000000589; Chromosome 13.
DR Bgee; ENSMUSG00000041685; Expressed in dorsal pancreas and 229 other cell types or tissues.
DR ExpressionAtlas; F6RG68; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd07673; F-BAR_FCHO2; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR030122; FCHo2_F-BAR.
DR PANTHER; PTHR23065:SF8; F-BAR DOMAIN ONLY PROTEIN 2; 1.
DR PANTHER; PTHR23065; PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1; 1.
DR Pfam; PF00611; FCH; 1.
DR SMART; SM00055; FCH; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR PROSITE; PS51741; F_BAR; 1.
PE 1: Evidence at protein level;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Proteomics identification {ECO:0007829|EPD:F6RG68,
KW ECO:0007829|MaxQB:F6RG68};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT DOMAIN 3..250
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
SQ SEQUENCE 356 AA; 40332 MW; 847AFAB090465C66 CRC64;
MVMAHFVENF WGEKNNGFDV LYHNMKHGQI STKELADFVR ERATIEEAYS RSMTKLAKSA
SNYSQLGTFA PMWDVFKTST EKLANCHLDL VRKLQELIKE VQKYGEEQVK SHKKTKEEVA
GTLEAVQAIQ NITQALQKSK ENYTAKCVEQ ERLKKEGATQ REIEKAAVKS KKATDTYKLY
VEKYALTKAD FEQKMTETAQ KFQDIEETHL IHIKEIIGSL SNAVKEIHLQ IGQVHEEFIN
NMANTTIESL IQKFAESKGT GKERPGLIEF EECDPASAVE GIKPRKRKTF ALPGIIKKEK
DAESVECPDA DSLKGSHCAA LAVLELNMQT RLSSNSKRSS RLYLPSAGVK EYSRCR
//
