ID F6RKZ0_ORNAN Unreviewed; 661 AA.
AC F6RKZ0;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 2.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Kelch repeat and BTB domain containing 3 {ECO:0000313|Ensembl:ENSOANP00000016584.3};
GN Name=KBTBD3 {ECO:0000313|Ensembl:ENSOANP00000016584.3};
OS Ornithorhynchus anatinus (Duckbill platypus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Monotremata; Ornithorhynchidae; Ornithorhynchus.
OX NCBI_TaxID=9258 {ECO:0000313|Ensembl:ENSOANP00000016584.3, ECO:0000313|Proteomes:UP000002279};
RN [1] {ECO:0000313|Ensembl:ENSOANP00000016584.3, ECO:0000313|Proteomes:UP000002279}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000016584.3,
RC ECO:0000313|Proteomes:UP000002279};
RX PubMed=18464734; DOI=10.1038/nature06936;
RA Warren W.C., Hillier L.W., Marshall Graves J.A., Birney E., Ponting C.P.,
RA Grutzner F., Belov K., Miller W., Clarke L., Chinwalla A.T., Yang S.P.,
RA Heger A., Locke D.P., Miethke P., Waters P.D., Veyrunes F., Fulton L.,
RA Fulton B., Graves T., Wallis J., Puente X.S., Lopez-Otin C., Ordonez G.R.,
RA Eichler E.E., Chen L., Cheng Z., Deakin J.E., Alsop A., Thompson K.,
RA Kirby P., Papenfuss A.T., Wakefield M.J., Olender T., Lancet D.,
RA Huttley G.A., Smit A.F., Pask A., Temple-Smith P., Batzer M.A.,
RA Walker J.A., Konkel M.K., Harris R.S., Whittington C.M., Wong E.S.,
RA Gemmell N.J., Buschiazzo E., Vargas Jentzsch I.M., Merkel A., Schmitz J.,
RA Zemann A., Churakov G., Kriegs J.O., Brosius J., Murchison E.P.,
RA Sachidanandam R., Smith C., Hannon G.J., Tsend-Ayush E., McMillan D.,
RA Attenborough R., Rens W., Ferguson-Smith M., Lefevre C.M., Sharp J.A.,
RA Nicholas K.R., Ray D.A., Kube M., Reinhardt R., Pringle T.H., Taylor J.,
RA Jones R.C., Nixon B., Dacheux J.L., Niwa H., Sekita Y., Huang X., Stark A.,
RA Kheradpour P., Kellis M., Flicek P., Chen Y., Webber C., Hardison R.,
RA Nelson J., Hallsworth-Pepin K., Delehaunty K., Markovic C., Minx P.,
RA Feng Y., Kremitzki C., Mitreva M., Glasscock J., Wylie T., Wohldmann P.,
RA Thiru P., Nhan M.N., Pohl C.S., Smith S.M., Hou S., Nefedov M.,
RA de Jong P.J., Renfree M.B., Mardis E.R., Wilson R.K.;
RT "Genome analysis of the platypus reveals unique signatures of evolution.";
RL Nature 453:175-183(2008).
RN [2] {ECO:0000313|Ensembl:ENSOANP00000016584.3}
RP IDENTIFICATION.
RC STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000016584.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F6RKZ0; -.
DR STRING; 9258.ENSOANP00000016584; -.
DR Ensembl; ENSOANT00000016587.3; ENSOANP00000016584.3; ENSOANG00000010467.3.
DR eggNOG; KOG4441; Eukaryota.
DR GeneTree; ENSGT00940000158415; -.
DR InParanoid; F6RKZ0; -.
DR OMA; KGKCCRK; -.
DR TreeFam; TF329218; -.
DR Proteomes; UP000002279; Chromosome 20.
DR Bgee; ENSOANG00000010467; Expressed in cerebellum and 6 other cell types or tissues.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR45632:SF3; KELCH-LIKE PROTEIN DIABLO; 1.
DR PANTHER; PTHR45632; LD33804P; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 1.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 3.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000002279};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 102..169
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT REGION 34..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..49
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 661 AA; 74268 MW; 4A41D4BEDC8D18E2 CRC64;
MSADDIVRED RLPLRRPLQE YVVPRDIQFL RDQLPHQQTA GLGSEEKRQT QVDSAMDHPS
DSTRRSTGGG IPEKKSDSVM AEEHGRRILS VLQSFRDQDM FYDFQIIVKD EIIPCHRCVL
AACSDFFRAM FQADMRERDG GSVTLGNLSP RAVRAFVDYA YAGETQITDD NVEMFFQLSS
FLQIPPLSEA CGDFLIKSID VANCLRLLSL SDGYGSAPLF EQALAFAERH FSSLLRSADF
LETNPGVLQR FLEADELDVP DEEAALRAVL RWTGHRPESR RKHLPRLMAK VRLHHLSEEA
LRGYLLSEDP LLGSTDGSAL IQEAVESVRE SAGLFADARP STTEKYIFVH KTEDAGEGRH
TFCYNVRTDE WKVLPRTQLL ALPGSSLSSC GEKIFVTGGC RGRCCRTTRL HVAESYHDAT
ERTWCYCPVS GEFSAVAGME RPRTMHASVM ALDRLFVIGG RTRGARETGS LLNVESYRPL
SGEWLPASRL PRGVYYPEAS ACRDAIYVLG SEVELSDAFS PSLDRFLRYN AATDQWSELV
AEFGQFLHAT LIKAVAVNCT LYVCDLSTYK VYSFCPETCV WKGEGSFECA GFNAGAVAVE
DKIYILGGDY APDEITDEVQ VYHSSRSEWE EVSPMPRALT EFYCQVIRFN KYRDPWSGDR
L
//
