ID F6RLY3_XENTR Unreviewed; 234 AA.
AC F6RLY3;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 4.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Methyltransferase-like 23 {ECO:0000313|Ensembl:ENSXETP00000042225};
DE SubName: Full=Methyltransferase-like protein 23 {ECO:0000313|RefSeq:XP_002935970.2};
GN Name=mettl23 {ECO:0000313|Ensembl:ENSXETP00000042225,
GN ECO:0000313|RefSeq:XP_002935970.2,
GN ECO:0000313|Xenbase:XB-GENE-6034943};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|Ensembl:ENSXETP00000042225};
RN [1] {ECO:0000313|Ensembl:ENSXETP00000042225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000042225};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [2] {ECO:0000313|Ensembl:ENSXETP00000042225}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUN-2011) to UniProtKB.
RN [3] {ECO:0000313|RefSeq:XP_002935970.2}
RP IDENTIFICATION.
RC STRAIN=Nigerian {ECO:0000313|RefSeq:XP_002935970.2};
RC TISSUE=Liver and blood {ECO:0000313|RefSeq:XP_002935970.2};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. METTL23
CC family. {ECO:0000256|ARBA:ARBA00043988}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_002935970.2; XM_002935924.5.
DR Ensembl; ENSXETT00000042225; ENSXETP00000042225; ENSXETG00000019499.
DR KEGG; xtr:100496624; -.
DR AGR; Xenbase:XB-GENE-6034943; -.
DR Xenbase; XB-GENE-6034943; mettl23.
DR eggNOG; KOG2793; Eukaryota.
DR HOGENOM; CLU_082022_1_0_1; -.
DR OMA; FYDPEDF; -.
DR OrthoDB; 91554at2759; -.
DR TreeFam; TF352729; -.
DR Proteomes; UP000008143; Chromosome 10.
DR Bgee; ENSXETG00000019499; Expressed in skeletal muscle tissue and 12 other cell types or tissues.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR019410; Methyltransf_16.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR14614; HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN; 1.
DR PANTHER; PTHR14614:SF130; HISTONE-ARGININE METHYLTRANSFERASE METTL23; 1.
DR Pfam; PF10294; Methyltransf_16; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|RefSeq:XP_002935970.2};
KW Reference proteome {ECO:0000313|Proteomes:UP000008143};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
SQ SEQUENCE 234 AA; 26135 MW; 8B9211BA309E3F2B CRC64;
MGEESEARIG ERVYTFLRGE GEEGREMCVT IPEVLDCQYG MYVWPCAVVL AQYLWCHRKD
LPNKRVLEVG AGVSLPGVLA AKCGAKVILS DSAELPQCLE NCRRSCNWNN ITGVPVVGLT
WGEISPELLD LPPIDIILGS DVFYEPKDFE DILLTVRFLM ERTPRAEFWT TYQVRSADWS
IEALLCKWNL KCTGVPLKTF GADRECLAGS ELPGRHTVQM MIITLDREAA GCTA
//
