ID F6RY57_HORSE Unreviewed; 643 AA.
AC F6RY57;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2023, sequence version 4.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=FAST kinase domains 2 {ECO:0000313|Ensembl:ENSECAP00000006917.4};
GN Name=FASTKD2 {ECO:0000313|VGNC:VGNC:17921};
OS Equus caballus (Horse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000006917.4, ECO:0000313|Proteomes:UP000002281};
RN [1] {ECO:0000313|Ensembl:ENSECAP00000006917.4, ECO:0000313|Proteomes:UP000002281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000006917.4,
RC ECO:0000313|Proteomes:UP000002281};
RX PubMed=19892987; DOI=10.1126/science.1178158;
RG Broad Institute Genome Sequencing Platform;
RG Broad Institute Whole Genome Assembly Team;
RA Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
RA Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O.,
RA Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.,
RA Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T.,
RA Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S.,
RA Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G.,
RA Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R.,
RA Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A.,
RA Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J.,
RA Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
RT "Genome sequence, comparative analysis, and population genetics of the
RT domestic horse.";
RL Science 326:865-867(2009).
RN [2] {ECO:0000313|Ensembl:ENSECAP00000006917.4}
RP IDENTIFICATION.
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000006917.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F6RY57; -.
DR STRING; 9796.ENSECAP00000006917; -.
DR PaxDb; 9796-ENSECAP00000006917; -.
DR Ensembl; ENSECAT00000009137.4; ENSECAP00000006917.4; ENSECAG00000008822.4.
DR VGNC; VGNC:17921; FASTKD2.
DR GeneTree; ENSGT01030000234607; -.
DR HOGENOM; CLU_025270_0_0_1; -.
DR InParanoid; F6RY57; -.
DR OMA; FEIRMDS; -.
DR TreeFam; TF352875; -.
DR Proteomes; UP000002281; Chromosome 18.
DR Bgee; ENSECAG00000008822; Expressed in gluteus medius and 23 other cell types or tissues.
DR GO; GO:0005759; C:mitochondrial matrix; IBA:GO_Central.
DR GO; GO:0035770; C:ribonucleoprotein granule; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0000963; P:mitochondrial RNA processing; IBA:GO_Central.
DR GO; GO:0044528; P:regulation of mitochondrial mRNA stability; IBA:GO_Central.
DR InterPro; IPR010622; FAST_Leu-rich.
DR PANTHER; PTHR21228:SF1; FAST KINASE DOMAIN-CONTAINING PROTEIN 2, MITOCHONDRIAL; 1.
DR PANTHER; PTHR21228; FAST LEU-RICH DOMAIN-CONTAINING; 1.
DR Pfam; PF06743; FAST_1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002281}.
FT DOMAIN 438..510
FT /note="FAST kinase leucine-rich"
FT /evidence="ECO:0000259|Pfam:PF06743"
SQ SEQUENCE 643 AA; 72814 MW; C40F0B337B89EA17 CRC64;
MSNRTGPFLW NLRQFSTLIP TSRTVRQYPL GLCRPQMAYS NWNPRNLLLN NFDNRLQAPV
RCLFQNALVF KSGDDFQTKG TSSVTVLTLD RLLCPRGLSF DSKHSLISDN GLKKISFHQE
ASSEDVLTKE TKPTPVTSRK LSQECNSLSD VLDTFSRAPK FPSSNYFSAM WTIAKRMSNE
QRRFEKQLMF NHPAFHQLCG QMMREAKIMR CDHLLFGLHA VVKLGIPQNT LLVQTLLRVV
QERINECDEK CLSVLSTVLE TMEPCKNVDV LRAGLRILAD QQVWKIERVF TLQAMMKCIG
KDAPMALKRK LEMKALRELD RFSLLNSQRM FEVLAAMGHC SVVLLDECSK MVVGNIHGCP
FKILISILQS CRDLRYRNLD LFKGIADYVA TTFDVWKLKQ VLFLLILFEN LGFRHVGLMD
LFMKKIVDEA GVLNVKSIVS ILHVYSSLNH FHTCQTREFL EAMAGALTGC LHQLSSENLL
NAVCSLCLMN RFPLAAVNQL LQKDVIGELL TSGDVERNVH KLHILAACLK LDDAPYHKAV
DLALPLLPPA PLPPNAKVAE ALSSLLGDGC FSKNVQLPHN YHIDFEIRMD TNRSQVLPFS
DVDLVNNWEM EKLEMEDAVT FLKTEIYSTE ALPTANANLQ STC
//
