ID   F6SID3_CALJA            Unreviewed;       548 AA.
AC   F6SID3;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   25-MAY-2022, sequence version 4.
DT   27-MAR-2024, entry version 65.
DE   SubName: Full=MAGUK p55 scaffold protein 2 {ECO:0000313|Ensembl:ENSCJAP00000019293.5};
GN   Name=MPP2 {ECO:0000313|Ensembl:ENSCJAP00000019293.5};
OS   Callithrix jacchus (White-tufted-ear marmoset).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Callitrichinae; Callithrix; Callithrix.
OX   NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000019293.5, ECO:0000313|Proteomes:UP000008225};
RN   [1] {ECO:0000313|Ensembl:ENSCJAP00000019293.5}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCJAP00000019293.5}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the MAGUK family.
CC       {ECO:0000256|ARBA:ARBA00007014}.
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DR   AlphaFoldDB; F6SID3; -.
DR   Ensembl; ENSCJAT00000020379.5; ENSCJAP00000019293.5; ENSCJAG00000010393.5.
DR   GeneTree; ENSGT00940000155348; -.
DR   HOGENOM; CLU_001715_5_1_1; -.
DR   Proteomes; UP000008225; Chromosome 5.
DR   Bgee; ENSCJAG00000010393; Expressed in frontal cortex and 5 other cell types or tissues.
DR   CDD; cd00071; GMPK; 1.
DR   CDD; cd00992; PDZ_signaling; 1.
DR   CDD; cd12037; SH3_MPP2; 1.
DR   Gene3D; 2.30.42.10; -; 1.
DR   Gene3D; 1.10.287.650; L27 domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 1.
DR   InterPro; IPR008145; GK/Ca_channel_bsu.
DR   InterPro; IPR008144; Guanylate_kin-like_dom.
DR   InterPro; IPR020590; Guanylate_kinase_CS.
DR   InterPro; IPR014775; L27_C.
DR   InterPro; IPR004172; L27_dom.
DR   InterPro; IPR036892; L27_dom_sf.
DR   InterPro; IPR035602; MPP2_SH3.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   PANTHER; PTHR23122:SF35; MAGUK P55 SUBFAMILY MEMBER 2; 1.
DR   PANTHER; PTHR23122; MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK; 1.
DR   Pfam; PF00625; Guanylate_kin; 1.
DR   Pfam; PF02828; L27; 2.
DR   Pfam; PF00595; PDZ; 1.
DR   Pfam; PF07653; SH3_2; 1.
DR   SMART; SM00072; GuKc; 1.
DR   SMART; SM00569; L27; 2.
DR   SMART; SM00228; PDZ; 1.
DR   SMART; SM00326; SH3; 1.
DR   SUPFAM; SSF101288; L27 domain; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF50156; PDZ domain-like; 1.
DR   SUPFAM; SSF50044; SH3-domain; 1.
DR   PROSITE; PS00856; GUANYLATE_KINASE_1; 1.
DR   PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
DR   PROSITE; PS51022; L27; 2.
DR   PROSITE; PS50106; PDZ; 1.
DR   PROSITE; PS50002; SH3; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}.
FT   DOMAIN          4..55
FT                   /note="L27"
FT                   /evidence="ECO:0000259|PROSITE:PS51022"
FT   DOMAIN          56..114
FT                   /note="L27"
FT                   /evidence="ECO:0000259|PROSITE:PS51022"
FT   DOMAIN          136..215
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          221..289
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   DOMAIN          346..533
FT                   /note="Guanylate kinase-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50052"
SQ   SEQUENCE   548 AA;  61175 MW;  554BB6EDB6E26E66 CRC64;
     LPPAQTAMQQ VLDNLGSLPN ATGAAELDLI FLRGIMESPI VRSLAKAHER LEETKLEAVR
     DNNLELVQEI LRDLAQLAEQ SSTAAELARI LQEPHFQSLL ETHDSVASKT YETPPPSPGL
     DPTFSNQPVP PDAVRMVGIR KTAGEHLGVT FRVEGGELVI ARILHGGMVA QQGLLHVGDI
     IKEVNGQLVG SDPRALQELL RNASGSVILK ILPSYQEPHL PRQVFVKCHF DYDPARDSLI
     PCKEAGLCFN AGDLLQIVNQ DDANWWQACH VEGGSAGLIP SQLLEEKRKA FVKRDLELTP
     NSGTLCGSLS GKKKKRMMYL TTKNAEFDRH ELLIYEEVAR MPPFRRKTLV LIGAQGVGRR
     SLKNKLIMWD PDRYGTTVPY TSRRPKDSER EGQGYSFVSR GEMEADIRAG RYLEHGEYEG
     NLYGTRIDSI RGVVAAGKVC VLDVNPQAVK VLRTAEFVPY VVFIEAPDFE TLRAMNRAAL
     ESGVSTKQLT EADLRRTVEE SSRIQRGYGH YFDLCLVNSN LERTFRELQA AMEKLRTEPQ
     WVPVSWVY
//