ID F6TTK4_CALJA Unreviewed; 423 AA.
AC F6TTK4;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 2.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Carbohydrate sulfotransferase {ECO:0000256|RuleBase:RU364020};
DE EC=2.8.2.- {ECO:0000256|RuleBase:RU364020};
GN Name=CHST8 {ECO:0000313|Ensembl:ENSCJAP00000019045.3};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000019045.3, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000019045.3}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000019045.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004323, ECO:0000256|RuleBase:RU364020}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004323,
CC ECO:0000256|RuleBase:RU364020}. Membrane
CC {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the sulfotransferase 2 family.
CC {ECO:0000256|ARBA:ARBA00006339, ECO:0000256|RuleBase:RU364020}.
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DR AlphaFoldDB; F6TTK4; -.
DR STRING; 9483.ENSCJAP00000019045; -.
DR Ensembl; ENSCJAT00000020117.4; ENSCJAP00000019045.3; ENSCJAG00000010344.6.
DR GeneTree; ENSGT00940000159100; -.
DR InParanoid; F6TTK4; -.
DR OMA; WAPDGHW; -.
DR Proteomes; UP000008225; Chromosome 22.
DR Bgee; ENSCJAG00000010344; Expressed in frontal cortex and 2 other cell types or tissues.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0001537; F:N-acetylgalactosamine 4-O-sulfotransferase activity; IEA:Ensembl.
DR GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR GO; GO:0042446; P:hormone biosynthetic process; IEA:Ensembl.
DR GO; GO:0030166; P:proteoglycan biosynthetic process; IEA:Ensembl.
DR GO; GO:0006790; P:sulfur compound metabolic process; IEA:Ensembl.
DR InterPro; IPR018011; Carb_sulfotrans_8-10.
DR InterPro; IPR005331; Sulfotransferase.
DR PANTHER; PTHR12137; CARBOHYDRATE SULFOTRANSFERASE; 1.
DR PANTHER; PTHR12137:SF7; CARBOHYDRATE SULFOTRANSFERASE 8; 1.
DR Pfam; PF03567; Sulfotransfer_2; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|RuleBase:RU364020};
KW Glycoprotein {ECO:0000256|RuleBase:RU364020};
KW Golgi apparatus {ECO:0000256|RuleBase:RU364020};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW Signal-anchor {ECO:0000256|RuleBase:RU364020};
KW Transferase {ECO:0000256|RuleBase:RU364020};
KW Transmembrane {ECO:0000256|RuleBase:RU364020}.
FT REGION 46..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 423 AA; 49088 MW; 1EE517662C99266F CRC64;
MTQRPRTMRL ACMFSSVLLF GAAGLLLFIS LQDPTELTSQ QAPGIKFSRP WQPHQDLPPG
GSKDSDLEVP TERVSRDLSS RAPRGLTLPV PDQPQPLLQR GTRLRLRQRR RRLLIKKMPA
VATILANSSE TPCIRPGPRT LDGRWISLHR SQQERKRVMQ EACAKYRASS NRRAITPRHV
SRIFVEDRHR VLYCEVPKAG CSNWKRVLMV LAGLASSTAD IQHNTVHYGS ALKRLDTFDR
QGILHRLSTY TKMLFVREPF ERLVSAFRDK FEHPNSYYHP VFGKAILARY RANASREALR
TGSGVRFPEF IQYLLDVHRP VGMDIHWDHV SRLCSPCLID YDFVGKFESM EEDANFFLSL
IHAPRNLTFP RFKDRHSQEA RTTARIAHQY FAQLSALQRQ RTYDFYYMDY LMFNYSKPFA
DLY
//
