ID F6TTX5_ORNAN Unreviewed; 495 AA.
AC F6TTX5;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 2.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Oxidative stress induced growth inhibitor 1 {ECO:0000313|Ensembl:ENSOANP00000003143.2};
GN Name=OSGIN1 {ECO:0000313|Ensembl:ENSOANP00000003143.2};
OS Ornithorhynchus anatinus (Duckbill platypus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Monotremata; Ornithorhynchidae; Ornithorhynchus.
OX NCBI_TaxID=9258 {ECO:0000313|Ensembl:ENSOANP00000003143.2, ECO:0000313|Proteomes:UP000002279};
RN [1] {ECO:0000313|Ensembl:ENSOANP00000003143.2, ECO:0000313|Proteomes:UP000002279}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000003143.2,
RC ECO:0000313|Proteomes:UP000002279};
RX PubMed=18464734; DOI=10.1038/nature06936;
RA Warren W.C., Hillier L.W., Marshall Graves J.A., Birney E., Ponting C.P.,
RA Grutzner F., Belov K., Miller W., Clarke L., Chinwalla A.T., Yang S.P.,
RA Heger A., Locke D.P., Miethke P., Waters P.D., Veyrunes F., Fulton L.,
RA Fulton B., Graves T., Wallis J., Puente X.S., Lopez-Otin C., Ordonez G.R.,
RA Eichler E.E., Chen L., Cheng Z., Deakin J.E., Alsop A., Thompson K.,
RA Kirby P., Papenfuss A.T., Wakefield M.J., Olender T., Lancet D.,
RA Huttley G.A., Smit A.F., Pask A., Temple-Smith P., Batzer M.A.,
RA Walker J.A., Konkel M.K., Harris R.S., Whittington C.M., Wong E.S.,
RA Gemmell N.J., Buschiazzo E., Vargas Jentzsch I.M., Merkel A., Schmitz J.,
RA Zemann A., Churakov G., Kriegs J.O., Brosius J., Murchison E.P.,
RA Sachidanandam R., Smith C., Hannon G.J., Tsend-Ayush E., McMillan D.,
RA Attenborough R., Rens W., Ferguson-Smith M., Lefevre C.M., Sharp J.A.,
RA Nicholas K.R., Ray D.A., Kube M., Reinhardt R., Pringle T.H., Taylor J.,
RA Jones R.C., Nixon B., Dacheux J.L., Niwa H., Sekita Y., Huang X., Stark A.,
RA Kheradpour P., Kellis M., Flicek P., Chen Y., Webber C., Hardison R.,
RA Nelson J., Hallsworth-Pepin K., Delehaunty K., Markovic C., Minx P.,
RA Feng Y., Kremitzki C., Mitreva M., Glasscock J., Wylie T., Wohldmann P.,
RA Thiru P., Nhan M.N., Pohl C.S., Smith S.M., Hou S., Nefedov M.,
RA de Jong P.J., Renfree M.B., Mardis E.R., Wilson R.K.;
RT "Genome analysis of the platypus reveals unique signatures of evolution.";
RL Nature 453:175-183(2008).
RN [2] {ECO:0000313|Ensembl:ENSOANP00000003143.2}
RP IDENTIFICATION.
RC STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000003143.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_001506208.2; XM_001506158.3.
DR AlphaFoldDB; F6TTX5; -.
DR STRING; 9258.ENSOANP00000003143; -.
DR Ensembl; ENSOANT00000003144.3; ENSOANP00000003143.2; ENSOANG00000001979.3.
DR eggNOG; ENOG502QRUQ; Eukaryota.
DR GeneTree; ENSGT00390000006658; -.
DR HOGENOM; CLU_019308_2_0_1; -.
DR InParanoid; F6TTX5; -.
DR OMA; ASWDIQT; -.
DR OrthoDB; 2896801at2759; -.
DR TreeFam; TF313502; -.
DR Proteomes; UP000002279; Chromosome X1.
DR Bgee; ENSOANG00000001979; Expressed in fibroblast and 7 other cell types or tissues.
DR GO; GO:0008083; F:growth factor activity; IBA:GO_Central.
DR GO; GO:0030308; P:negative regulation of cell growth; IBA:GO_Central.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:Ensembl.
DR GO; GO:0030334; P:regulation of cell migration; IEA:Ensembl.
DR GO; GO:0042127; P:regulation of cell population proliferation; IEA:Ensembl.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR029731; OKL38_fam.
DR PANTHER; PTHR15192:SF15; OXIDATIVE STRESS-INDUCED GROWTH INHIBITOR 1; 1.
DR PANTHER; PTHR15192; PROTEIN CBG05349; 1.
DR Pfam; PF13738; Pyr_redox_3; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002279}.
SQ SEQUENCE 495 AA; 54555 MW; 6FDC7DC58040453C CRC64;
MSSVWKEHPS LSSSKPLPVV IIGNGPSGIC LSYLLSGYTP YVRRDAVHPH PILQKKLEET
PEVSIIDQDL EYLSEGLEGR CYSPVALLFD TLLRPDTDIG GSAESVLTWW HQENRAIPHL
VLGKNLPGGA WHSIEGSMIT LSQGEWMGLP DLQFKDWMKK KRRGFRNSRA TAGDIAHYYQ
NYVMKKGLYH NFHCGSTVTA VRRVGPRQEL GSGPDCFSDW SAQEPAACQA APDQQLFQVS
GFTEGSDGSQ QPFSVSAENV VLATGTYDSP AWLGIPGEDL PFVHHELSVL ETSTKDGTLD
QTSDPVLIVG AGLSAADAVL FARHCNVPVI HAFRRKVDDP GLIFNQLPKM MYPEYHKVHQ
MMREQSILTL GSYEGYLSLP EHQLLFFKDD KRCVFQDGRG QQKVFSISLA LLLIGSNPNL
SFLPDNGADL AVDPLKPVNP KRNPIDVAPF TYECVQEPGL YALGPLAGDN FVRFVQGGAL
AVASSLLRKE KKNPT
//
