ID F6TVE9_CIOIN Unreviewed; 815 AA.
AC F6TVE9;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 2.
DT 27-MAR-2024, entry version 71.
DE RecName: Full=C2H2-type domain-containing protein {ECO:0000259|PROSITE:PS50157};
GN Name=zf(c2h2)-26 {ECO:0000313|Ensembl:ENSCINP00000003482.3};
OS Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis).
OC Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
OC Cionidae; Ciona.
OX NCBI_TaxID=7719 {ECO:0000313|Ensembl:ENSCINP00000003482.3, ECO:0000313|Proteomes:UP000008144};
RN [1] {ECO:0000313|Proteomes:UP000008144}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12481130; DOI=10.1126/science.1080049;
RA Dehal P., Satou Y., Campbell R.K., Chapman J., Degnan B., De Tomaso A.,
RA Davidson B., Di Gregorio A., Gelpke M., Goodstein D.M., Harafuji N.,
RA Hastings K.E., Ho I., Hotta K., Huang W., Kawashima T., Lemaire P.,
RA Martinez D., Meinertzhagen I.A., Necula S., Nonaka M., Putnam N., Rash S.,
RA Saiga H., Satake M., Terry A., Yamada L., Wang H.G., Awazu S., Azumi K.,
RA Boore J., Branno M., Chin-Bow S., DeSantis R., Doyle S., Francino P.,
RA Keys D.N., Haga S., Hayashi H., Hino K., Imai K.S., Inaba K., Kano S.,
RA Kobayashi K., Kobayashi M., Lee B.I., Makabe K.W., Manohar C., Matassi G.,
RA Medina M., Mochizuki Y., Mount S., Morishita T., Miura S., Nakayama A.,
RA Nishizaka S., Nomoto H., Ohta F., Oishi K., Rigoutsos I., Sano M.,
RA Sasaki A., Sasakura Y., Shoguchi E., Shin-i T., Spagnuolo A., Stainier D.,
RA Suzuki M.M., Tassy O., Takatori N., Tokuoka M., Yagi K., Yoshizaki F.,
RA Wada S., Zhang C., Hyatt P.D., Larimer F., Detter C., Doggett N.,
RA Glavina T., Hawkins T., Richardson P., Lucas S., Kohara Y., Levine M.,
RA Satoh N., Rokhsar D.S.;
RT "The draft genome of Ciona intestinalis: insights into chordate and
RT vertebrate origins.";
RL Science 298:2157-2167(2002).
RN [2] {ECO:0000313|Ensembl:ENSCINP00000003482.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; EAAA01001651; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; F6TVE9; -.
DR Ensembl; ENSCINT00000003482.3; ENSCINP00000003482.3; ENSCING00000001724.3.
DR GeneTree; ENSGT00390000000546; -.
DR HOGENOM; CLU_013403_0_0_1; -.
DR InParanoid; F6TVE9; -.
DR OMA; FPPDENK; -.
DR TreeFam; TF333164; -.
DR Proteomes; UP000008144; Chromosome 3.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IBA:GO_Central.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 8.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24394:SF29; GM08392P; 1.
DR PANTHER; PTHR24394; ZINC FINGER PROTEIN; 1.
DR Pfam; PF00096; zf-C2H2; 6.
DR Pfam; PF13912; zf-C2H2_6; 1.
DR SMART; SM00355; ZnF_C2H2; 13.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 6.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 10.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 10.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Reference proteome {ECO:0000313|Proteomes:UP000008144};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 363..390
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 391..413
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 443..470
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 501..529
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 563..591
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 594..621
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 622..649
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 650..682
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 684..707
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 710..739
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 331..357
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 726..765
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 331..350
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 726..742
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 815 AA; 92494 MW; 6E7EB2C373259E2E CRC64;
MQSYFETLNV NEITAHGSLA FLESASLTGE SQSGLASNLV QLSGEENISQ PQGLQENAIE
NVVEDGDIFQ CGRCKQQFNN LNIFVQHKTD HCSMQRHIYE QNGPPQILGG NQLSSSLADH
TLLYEQAHVV LADNCNDVHG RPIHGGMLHQ QNISSAHPNS LPINPRTSQT NACQSNIPIH
RRILPMPYNG NHPHPPQHRI LLPRAQQMPI SAPHTRINLS DDLLASEPRE ATEDDMTVGG
NGLISSLLQQ IPPFQPVGAH QSNSNANLPS EQMAITTTTT STVQIIAETD NTNHVDMQSS
MLEEHSQPIR TQASKSRGKT LETILPRLYD RNNNATSTSG SAPTILESPE STSEQKDDTK
KKFTCQFCQK VFTKNFDLEQ HKRSHTGEKP FQCIVCGRAF AQKSNVKKHM VSHKVWLKGT
ATFSQACSKD NNSGVPDSVD VSFNCQYCGE SFPSYNKRKS HMQVHKDQQV YKCLKEECSL
TFRDLDAFIA HVKGHETGMT YRCHQCHKVF KSLHDLGLHQ YQVHLNSRKK SIQTKTYPCQ
LCPSKFSHPT ALREHVINDP HHHVCRICDA TFTCERYLRK HTFMQHKEEN AKGATCTVCG
KSLRSVYYLR LHMFIHTKEL PYRCTKCDAA FNRKDKVKRH MLTHDPVKRF KCPLRNVLEC
NKEFSRADKL KEHIINHSRT KRTYSCSTCS KKYSRESCLI RHEKIHSYPF HCNTCTQSFP
TESKLKGHKC HKRRKSQTPK KVKPSPKKVP PSNQVVEETS ETNCHDRSEP VYTRLWPLVN
PQCEQPTSPV KVQITIDDDN EVTMTRDCDV SQVAE
//
