ID F6U5C2_HORSE Unreviewed; 268 AA.
AC F6U5C2;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2023, sequence version 4.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Calcium voltage-gated channel auxiliary subunit alpha2delta 4 {ECO:0000313|Ensembl:ENSECAP00000020725.4};
GN Name=CACNA2D4 {ECO:0000313|VGNC:VGNC:56541};
OS Equus caballus (Horse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000020725.4, ECO:0000313|Proteomes:UP000002281};
RN [1] {ECO:0000313|Ensembl:ENSECAP00000020725.4, ECO:0000313|Proteomes:UP000002281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000020725.4,
RC ECO:0000313|Proteomes:UP000002281};
RX PubMed=19892987; DOI=10.1126/science.1178158;
RG Broad Institute Genome Sequencing Platform;
RG Broad Institute Whole Genome Assembly Team;
RA Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
RA Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O.,
RA Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.,
RA Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T.,
RA Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S.,
RA Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G.,
RA Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R.,
RA Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A.,
RA Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J.,
RA Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
RT "Genome sequence, comparative analysis, and population genetics of the
RT domestic horse.";
RL Science 326:865-867(2009).
RN [2] {ECO:0000313|Ensembl:ENSECAP00000020725.4}
RP IDENTIFICATION.
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000020725.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F6U5C2; -.
DR STRING; 9796.ENSECAP00000020725; -.
DR PaxDb; 9796-ENSECAP00000020725; -.
DR Ensembl; ENSECAT00000024925.4; ENSECAP00000020725.4; ENSECAG00000022862.4.
DR VGNC; VGNC:56541; CACNA2D4.
DR GeneTree; ENSGT00940000155997; -.
DR InParanoid; F6U5C2; -.
DR OMA; EIHRIHA; -.
DR TreeFam; TF315824; -.
DR Proteomes; UP000002281; Chromosome 6.
DR Bgee; ENSECAG00000022862; Expressed in retina and 7 other cell types or tissues.
DR GO; GO:0005891; C:voltage-gated calcium channel complex; IBA:GO_Central.
DR GO; GO:0005245; F:voltage-gated calcium channel activity; IBA:GO_Central.
DR InterPro; IPR013680; VDCC_a2/dsu.
DR PANTHER; PTHR10166; VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED; 1.
DR PANTHER; PTHR10166:SF59; VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2_DELTA-4; 1.
DR Pfam; PF08473; VGCC_alpha2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002281}.
FT DOMAIN 14..241
FT /note="Voltage-dependent calcium channel alpha-2/delta
FT subunit conserved region"
FT /evidence="ECO:0000259|Pfam:PF08473"
SQ SEQUENCE 268 AA; 30346 MW; C0CA7240EB5F4664 CRC64;
MRLEFLQRTF WAATQQDLDC FVIDNNGFIL ISEMSQEVGR FLGEVDGALM TQLLSMGVFS
QVTMYDYQAM CKLQNHHPSA ARPLVSPVSA LLTATRWLVN ELLLFLLEWS AWGSWHVDRG
AEAKAVFHHS HKHKKQDTLQ PCDTEYPVFV HQMAIRETNG VIECGACQKI FVMQQIPNSN
LLLLVTDTTC DCSIFPLILQ EATEVKYNAS VKCDRMRSQK LRRRPGSCHA FHPEENAQDC
GGTSDTSASF TLLLLPLCAW VLPPQLLW
//
