ID F6U786_MOUSE Unreviewed; 189 AA.
AC F6U786;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Rho guanine nucleotide exchange factor (GEF) 38 {ECO:0000313|Ensembl:ENSMUSP00000054558.4};
GN Name=Arhgef38 {ECO:0000313|Ensembl:ENSMUSP00000054558.4,
GN ECO:0000313|MGI:MGI:1924919};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000054558.4, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000054558.4, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000054558.4,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000054558.4}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000054558.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F6U786; -.
DR MaxQB; F6U786; -.
DR ProteomicsDB; 324628; -.
DR Antibodypedia; 50147; 12 antibodies from 7 providers.
DR Ensembl; ENSMUST00000054105.4; ENSMUSP00000054558.4; ENSMUSG00000040969.15.
DR AGR; MGI:1924919; -.
DR MGI; MGI:1924919; Arhgef38.
DR VEuPathDB; HostDB:ENSMUSG00000040969; -.
DR GeneTree; ENSGT00950000183088; -.
DR HOGENOM; CLU_103798_0_0_1; -.
DR ChiTaRS; Arhgef38; mouse.
DR Proteomes; UP000000589; Chromosome 3.
DR Bgee; ENSMUSG00000040969; Expressed in epiblast cell in embryo and 17 other cell types or tissues.
DR ExpressionAtlas; F6U786; baseline and differential.
DR Gene3D; 2.30.30.40; SH3 Domains; 2.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR22834; NUCLEAR FUSION PROTEIN FUS2; 1.
DR PANTHER; PTHR22834:SF17; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 38; 1.
DR Pfam; PF07653; SH3_2; 1.
DR Pfam; PF14604; SH3_9; 1.
DR SMART; SM00326; SH3; 2.
DR SUPFAM; SSF50044; SH3-domain; 2.
DR PROSITE; PS50002; SH3; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|ProteomicsDB:F6U786};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 1..61
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
SQ SEQUENCE 189 AA; 21407 MW; 520858EEE3603E8F CRC64;
ELYRAKRKCN ATQEHDINLL EGELVAVLEQ KDPLGSTSRW FVDTGCVKGY VYSSFLKPHN
PGKGQKVDAD NRFCDDDFEN ISLFVSCRPA GDRVSISDSS SSLSGSCGKF ETNGADADNF
QEVDEQIFYA VHAFQARSDH ELSLQEYQRV HILRFCDLSG NKEWWLAEAQ GQKGYVPQLP
WEDDVCLRK
//
