ID F6UTB7_XENTR Unreviewed; 558 AA.
AC F6UTB7;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 4.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=Carboxypeptidase N subunit 2 {ECO:0000313|Ensembl:ENSXETP00000014516, ECO:0000313|RefSeq:XP_031758236.1};
GN Name=cpn2.2 {ECO:0000313|Ensembl:ENSXETP00000014516,
GN ECO:0000313|RefSeq:XP_031758236.1,
GN ECO:0000313|Xenbase:XB-GENE-6463914};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|Ensembl:ENSXETP00000014516};
RN [1] {ECO:0000313|Ensembl:ENSXETP00000014516}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000014516};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [2] {ECO:0000313|Ensembl:ENSXETP00000014516}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUN-2011) to UniProtKB.
RN [3] {ECO:0000313|RefSeq:XP_031758236.1}
RP IDENTIFICATION.
RC STRAIN=Nigerian {ECO:0000313|RefSeq:XP_031758236.1};
RC TISSUE=Liver and blood {ECO:0000313|RefSeq:XP_031758236.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_031758236.1; XM_031902376.1.
DR Ensembl; ENSXETT00000014516; ENSXETP00000014516; ENSXETG00000030284.
DR KEGG; xtr:101732575; -.
DR Xenbase; XB-GENE-6463914; cpn2.2.
DR eggNOG; KOG0619; Eukaryota.
DR HOGENOM; CLU_000288_18_6_1; -.
DR OMA; REVFCSD; -.
DR TreeFam; TF351124; -.
DR Reactome; R-XTR-977606; Regulation of Complement cascade.
DR Proteomes; UP000008143; Chromosome 5.
DR Bgee; ENSXETG00000030284; Expressed in liver and 1 other cell type or tissue.
DR GO; GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR45842:SF6; LEUCINE-RICH REPEAT AND FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR45842; SYNAPTIC ADHESION-LIKE MOLECULE SALM; 1.
DR Pfam; PF13855; LRR_8; 3.
DR SMART; SM00369; LRR_TYP; 12.
DR SMART; SM00082; LRRCT; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 3.
PE 4: Predicted;
KW Carboxypeptidase {ECO:0000313|RefSeq:XP_031758236.1};
KW Hydrolase {ECO:0000313|RefSeq:XP_031758236.1};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Protease {ECO:0000313|RefSeq:XP_031758236.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008143};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 424..475
FT /note="LRRCT"
FT /evidence="ECO:0000259|SMART:SM00082"
SQ SEQUENCE 558 AA; 63435 MW; DCA08EF7E5DE1FE0 CRC64;
MSLEMFSVLL TDKACGFHSD LTLKMVSNIP WSVLTFAWWL TVHSWFAWSC PDSCDCFRRV
KIFCTSSAIK EVPSNISVTV TELVFLETHI GTIGNTTFMG KDRLKKLVFI SNQIKSIDVG
ALHWFPKLTD LEITANPLSE IHPGTFDNLP ELLKLTVTFN YIEELPCELL QKTQNLQILI
LQGNNISALC SEMFSSIKNL VELSLDSNGI MHLPVDLFKP LQKLRVLKLS NNKLSKLPPG
IFDCLKELSE LYLNGNGLTT IPGHTFEKLT SLKKLMLMSN SIKMLSDGIF SALVNLTILR
LDWNRLEYLP FGIFNETTSL HILSINGNRL QAIPEGIFSR LHHVKKLDLC SNLLEKLQNS
TFQGLHSLTH LHLDNNNLTF IENNVFKDLN DLKMLTLHHN NLTTILDGTF DPLFNVASLV
LHSNPWLCDC SFMYLLKWIK ENSDFTQVSE MQCEKPQHLK EKALSLLRKQ DLSCPTNTRI
HVPDIPSTND QRVMKNAPLS PCYLTTNGDL HLTCKVNVCK SMRIHVSLQR ESNTTTFVRD
FGNFQPHCTD VIFNITIN
//
