ID F6UYC1_MOUSE Unreviewed; 150 AA.
AC F6UYC1;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=HECT, UBA and WWE domain containing 1 {ECO:0000313|Ensembl:ENSMUSP00000118185.2};
DE Flags: Fragment;
GN Name=Huwe1 {ECO:0000313|Ensembl:ENSMUSP00000118185.2,
GN ECO:0000313|MGI:MGI:1926884};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000118185.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000118185.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000118185.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000118185.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000118185.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F6UYC1; -.
DR SMR; F6UYC1; -.
DR MaxQB; F6UYC1; -.
DR PeptideAtlas; F6UYC1; -.
DR ProteomicsDB; 371839; -.
DR Antibodypedia; 448; 208 antibodies from 35 providers.
DR Ensembl; ENSMUST00000123306.2; ENSMUSP00000118185.2; ENSMUSG00000025261.19.
DR AGR; MGI:1926884; -.
DR MGI; MGI:1926884; Huwe1.
DR VEuPathDB; HostDB:ENSMUSG00000025261; -.
DR GeneTree; ENSGT00940000156319; -.
DR HOGENOM; CLU_1744746_0_0_1; -.
DR ChiTaRS; Huwe1; mouse.
DR Proteomes; UP000000589; Chromosome X.
DR Bgee; ENSMUSG00000025261; Expressed in embryonic post-anal tail and 265 other cell types or tissues.
DR ExpressionAtlas; F6UYC1; baseline and differential.
DR InterPro; IPR010314; E3_Ub_ligase_DUF913.
DR Pfam; PF06025; DUF913; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:F6UYC1,
KW ECO:0007829|MaxQB:F6UYC1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT DOMAIN 2..131
FT /note="DUF913"
FT /evidence="ECO:0000259|Pfam:PF06025"
FT REGION 17..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 54..73
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000118185.2"
SQ SEQUENCE 150 AA; 16410 MW; 2FD0E2EADD0F8DC2 CRC64;
LLEEICNLGR DPKYICQKPS IQKADGTATA PPPRSNHAAE EASSEDEEEE EVQAMQSFNS
AQQNETEPNQ QVVGTEERIP IPLMDYILNV MKFVESILSN NTTDDHCQEF VNQKGLLPLV
TILGLPNLPI DFPTSAACQA VAGVCKSILV
//
