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Database: UniProt
Entry: F6V4P5_XENTR
LinkDB: F6V4P5_XENTR
Original site: F6V4P5_XENTR 
ID   F6V4P5_XENTR            Unreviewed;       625 AA.
AC   F6V4P5;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   27-JUL-2011, sequence version 1.
DT   20-JUN-2018, entry version 42.
DE   SubName: Full=SH2B adaptor protein 2 {ECO:0000313|Ensembl:ENSXETP00000012035};
GN   Name=sh2b2 {ECO:0000313|Ensembl:ENSXETP00000012035,
GN   ECO:0000313|Xenbase:XB-GENE-494880};
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus;
OC   Silurana.
OX   NCBI_TaxID=8364 {ECO:0000313|Ensembl:ENSXETP00000012035, ECO:0000313|Proteomes:UP000008143};
RN   [1] {ECO:0000313|Ensembl:ENSXETP00000012035}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000012035};
RX   PubMed=20431018; DOI=10.1126/science.1183670;
RA   Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA   Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L.,
RA   Blitz I.L., Blumberg B., Dichmann D.S., Dubchak I., Amaya E.,
RA   Detter J.C., Fletcher R., Gerhard D.S., Goodstein D., Graves T.,
RA   Grigoriev I.V., Grimwood J., Kawashima T., Lindquist E., Lucas S.M.,
RA   Mead P.E., Mitros T., Ogino H., Ohta Y., Poliakov A.V., Pollet N.,
RA   Robert J., Salamov A., Sater A.K., Schmutz J., Terry A., Vize P.D.,
RA   Warren W.C., Wells D., Wills A., Wilson R.K., Zimmerman L.B.,
RA   Zorn A.M., Grainger R., Grammer T., Khokha M.K., Richardson P.M.,
RA   Rokhsar D.S.;
RT   "The genome of the Western clawed frog Xenopus tropicalis.";
RL   Science 328:633-636(2010).
RN   [2] {ECO:0000313|Ensembl:ENSXETP00000012035}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUN-2011) to UniProtKB.
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DR   EMBL; AAMC01123603; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 8364.ENSXETP00000012035; -.
DR   PaxDb; F6V4P5; -.
DR   Ensembl; ENSXETT00000012035; ENSXETP00000012035; ENSXETG00000005475.
DR   Xenbase; XB-GENE-494880; sh2b2.
DR   eggNOG; ENOG410IMWK; Eukaryota.
DR   eggNOG; ENOG41102PH; LUCA.
DR   GeneTree; ENSGT00530000063355; -.
DR   InParanoid; F6V4P5; -.
DR   OMA; YDTEFFR; -.
DR   OrthoDB; EOG091G04RI; -.
DR   TreeFam; TF323184; -.
DR   Proteomes; UP000008143; Unassembled WGS sequence.
DR   Bgee; ENSXETG00000005475; -.
DR   GO; GO:0035591; F:signaling adaptor activity; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd10411; SH2_SH2B2; 1.
DR   Gene3D; 2.30.29.30; -; 1.
DR   Gene3D; 3.30.505.10; -; 1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR015012; Phe_ZIP.
DR   InterPro; IPR036290; Phe_ZIP_sf.
DR   InterPro; IPR000980; SH2.
DR   InterPro; IPR036860; SH2_dom_sf.
DR   InterPro; IPR030523; SH2B.
DR   InterPro; IPR030520; SH2B2.
DR   InterPro; IPR035058; SH2B2_SH2.
DR   PANTHER; PTHR10872; PTHR10872; 1.
DR   PANTHER; PTHR10872:SF4; PTHR10872:SF4; 1.
DR   Pfam; PF00169; PH; 1.
DR   Pfam; PF08916; Phe_ZIP; 1.
DR   Pfam; PF00017; SH2; 1.
DR   PRINTS; PR00401; SH2DOMAIN.
DR   SMART; SM00233; PH; 1.
DR   SMART; SM00252; SH2; 1.
DR   SUPFAM; SSF109805; SSF109805; 1.
DR   SUPFAM; SSF55550; SSF55550; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
DR   PROSITE; PS50001; SH2; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008143};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008143};
KW   SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT   DOMAIN      200    313       PH. {ECO:0000259|PROSITE:PS50003}.
FT   DOMAIN      417    515       SH2. {ECO:0000259|PROSITE:PS50001}.
SQ   SEQUENCE   625 AA;  69871 MW;  ECAE79A263986523 CRC64;
     MNGDAVSKDS SSQPPDWKEF CELHAQAAAV DFAQKFCRFL KENPHYNAPG AETSFSHHFA
     ANFLDFFSFE VSRVYVSDSP TNMDNPVTNR YLSRTQARVH KVSSYGHSRS SEDVSVHDSS
     KSKFKKGFSL RNMSLCVVDG VKEMWHRKSS PEPSLDNGTI RRSDREHCTS GSKEHVEPRE
     KWTQKLRLSK MQASKIDVVD IQREGTLRYM VADDSNCVGS SQWQKCRLLL RKAVKMEGER
     FLLEFYVPPK SSKPKVSIPL SAILEVRTTM PLEMPDKDNT FVLKVENSAE YILETIDSLQ
     KHSWVADIQD CIDPGDSGDD IELSSCEQGT CLAGQASSCS CEFLADGDIN FPGASAVPPH
     PTCAPPQPRN RDMSSAEHLI HVPLEHFLQT LEPPTSNHLP GEEGEEEIEI NLSDFPWFHG
     TLSRIRAAQL VLSGGTRSHG LFVIRQSETR PGEYVLTFNF QGKAKHLRLS LNETGQCHVQ
     HLWFQTIFDM LKHFHSHPIP LESGGSADIT LRSFVVAQRQ LSADPAPPQN VSVQQQNCRT
     ETQSQHYFTS SGASNMQPVS PPESSASAPA PHPAYHRVEG TLGTRSRSNS AELLLESPNG
     STEDYHESDG SRSRTRAVEN QYSFY
//
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