ID F6V7S3_MACMU Unreviewed; 1437 AA.
AC F6V7S3;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 3.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Myomesin 3 {ECO:0000313|Ensembl:ENSMMUP00000030348.4};
GN Name=MYOM3 {ECO:0000313|Ensembl:ENSMMUP00000030348.4,
GN ECO:0000313|VGNC:VGNC:75030};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|Ensembl:ENSMMUP00000030348.4, ECO:0000313|Proteomes:UP000006718};
RN [1] {ECO:0000313|Proteomes:UP000006718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=17573 {ECO:0000313|Proteomes:UP000006718};
RX PubMed=17431167; DOI=10.1126/science.1139247;
RA Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M.,
RA Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C., Wilson R.K.,
RA Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W., Hardison R.C.,
RA Makova K.D., Miller W., Milosavljevic A., Palermo R.E., Siepel A.,
RA Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J.,
RA Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y., Dinh H.H.,
RA Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T., Godfrey J.,
RA Hawes A.C., Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N.,
RA Joshi V., Khan Z.M., Kirkness E.F., Cree A., Fowler R.G., Lee S.,
RA Lewis L.R., Li Z., Liu Y.-S., Moore S.M., Muzny D., Nazareth L.V.,
RA Ngo D.N., Okwuonu G.O., Pai G., Parker D., Paul H.A., Pfannkoch C.,
RA Pohl C.S., Rogers Y.-H.C., Ruiz S.J., Sabo A., Santibanez J.,
RA Schneider B.W., Smith S.M., Sodergren E., Svatek A.F., Utterback T.R.,
RA Vattathil S., Warren W., White C.S., Chinwalla A.T., Feng Y., Halpern A.L.,
RA Hillier L.W., Huang X., Minx P., Nelson J.O., Pepin K.H., Qin X.,
RA Sutton G.G., Venter E., Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P.,
RA Jones S.M., Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L.,
RA Csuros M., Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H.,
RA Liu Y., Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E.,
RA Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J.,
RA Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J.,
RA Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A.,
RA Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J., Denby A.,
RA Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A., Marklein A.,
RA Nielsen R., Vallender E.J., Clark A.G., Ferguson B., Hernandez R.D.,
RA Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S., Pu L.-L., Ren Y.,
RA Smith D.G., Wheeler D.A., Schenck I., Ball E.V., Chen R., Cooper D.N.,
RA Giardine B., Hsu F., Kent W.J., Lesk A., Nelson D.L., O'brien W.E.,
RA Pruefer K., Stenson P.D., Wallace J.C., Ke H., Liu X.-M., Wang P.,
RA Xiang A.P., Yang F., Barber G.P., Haussler D., Karolchik D., Kern A.D.,
RA Kuhn R.M., Smith K.E., Zwieg A.S.;
RT "Evolutionary and biomedical insights from the rhesus macaque genome.";
RL Science 316:222-234(2007).
RN [2] {ECO:0000313|Ensembl:ENSMMUP00000030348.4}
RP IDENTIFICATION.
RC STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000030348.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR STRING; 9544.ENSMMUP00000030348; -.
DR PaxDb; 9544-ENSMMUP00000030348; -.
DR Ensembl; ENSMMUT00000032435.4; ENSMMUP00000030348.4; ENSMMUG00000023052.4.
DR VEuPathDB; HostDB:ENSMMUG00000023052; -.
DR VGNC; VGNC:75030; MYOM3.
DR eggNOG; ENOG502RDUJ; Eukaryota.
DR GeneTree; ENSGT00940000158669; -.
DR HOGENOM; CLU_004753_1_0_1; -.
DR OrthoDB; 198115at2759; -.
DR TreeFam; TF331825; -.
DR Proteomes; UP000006718; Chromosome 1.
DR Bgee; ENSMMUG00000023052; Expressed in heart and 9 other cell types or tissues.
DR ExpressionAtlas; F6V7S3; baseline.
DR GO; GO:0031430; C:M band; IEA:Ensembl.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR CDD; cd00063; FN3; 5.
DR Gene3D; 2.60.40.10; Immunoglobulins; 12.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR13817:SF89; MYOMESIN-3; 1.
DR PANTHER; PTHR13817; TITIN; 1.
DR Pfam; PF00041; fn3; 5.
DR Pfam; PF07679; I-set; 4.
DR PRINTS; PR00014; FNTYPEIII.
DR SMART; SM00060; FN3; 5.
DR SMART; SM00409; IG; 6.
DR SMART; SM00408; IGc2; 4.
DR SUPFAM; SSF49265; Fibronectin type III; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 6.
DR PROSITE; PS50853; FN3; 5.
DR PROSITE; PS50835; IG_LIKE; 4.
PE 4: Predicted;
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Reference proteome {ECO:0000313|Proteomes:UP000006718};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 154..246
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 269..347
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 375..469
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 503..597
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 604..696
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 702..797
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 804..899
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1120..1205
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1334..1423
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 1..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..48
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1437 AA; 161931 MW; 9667E483C3CB5D0F CRC64;
MTLPHSLGGA GDPRPPQTME VHRLEHRQEE ERKEERQHSL RMGSSVRRHT FRSSEEEHEF
SAADYALAAA LALTASSELS WEAQLRRQTS AVELEERGQK RVGFGNDWER TEIAFLRTHR
LLRQRRNWKM LRQRTEEKVQ EAKELRELCS GRGPWFWIPL RSHAVWEHTT VLLTCTVQAS
PPPQVTWYKN DTRIDPRLFP AGKYRITNNY GLLSLEIRRC TIEDSATYTV RVKNAYGQAS
SFAKVLVRTY LGKDAGFDSE IFKRSMFGPS VEFTSVLKPV FAREKEPFSL SCLFSEDVLD
AESIQWFRDG RLLRSSRRRK ILYADCQASL KVSCTYKEDE GLYTVQVPSP FGPREQSTYV
LVRDAEAENP GAPGSPLNVR CLDVNRDCLI LTWAPPSDTR GNAITAYSIE RCQGDSGEWV
PCHEAPGGTC RCPIQGLVEG QSYRFRVRAI SKAGSSLPSK ASELVVMGDH DAARRKTEIP
FGLGNKITIS TDDFEDTVTI PSPPTNVHAS EIREAYVVLA WEEPRPRGRA PLTYSLEKSV
IGSGTWEAIS TESPVKSPRF TVLDLEKKKS YVFRVRAMNQ YGLSDPSEPS EPIALPGQPA
TLPPPAQVQA FRDTQTSVTL TWDPVKDPEL LGYYIYSREV GSSEWQTVNN KPIQGTRFTV
PGLRTGKEYE FCVRSVSEAG VGESSAATEP IRVKQALATP SAPYGFALLN CGKNEMVIGW
KPPKRRGGGK ILGYFLDQHD SEELDWHAVN QQPIPTRVCK VSDLREGHFY EFRARAANWA
GVGELSAPSS LFECKEWTMP QPGPPYDVRV SEVRATSLVL QWEPPLYTGA GPVTGYHVSF
QEEGSEQWKP VTPGPISGTH LRVSDLQPGK SYVFQVQAMN SAGLGQPSMP TDPVLLEDKP
GAHEIEVGVD EEGFIYLAFE APEAPDSSEF QWSKDYKGPL DPQRVTIEDT VNKSKVILKE
PGLEDLGTYS VIVTDADEDI SASHTLTEEE LEKLKKLSHE IRNPVIKLIS GWNVDILERG
EVRLWLEVEK LSPAAELHLI FNNKEIFSSP NRKINFDREK GLVEVIIQNL SEEDKGSYTA
QLQDGKAKNQ ITLTLVDDDF DKLLRQADAK RRDWKRKQGP YFEQPLQWKV TEDCQVQLTC
KVTNTKKETR FQWFFQRAEL PDGQYDPETG TGLLCIEELS KKDKGIYRAM VSDDRGEDDT
ILDLTGDALD AIFTELGRIG ALSATPLKIQ GTEEGIRIFS KVKYYNVEYM KTTWFHKDKR
LESGDRIRTG TTLDEIWLHI LDPKDSDKGK YTLEIAAGKE FRQLSTDLSG QAFEDAMAEH
QRLKALAIIE KNRAKVVRGL PDVATIMEDK TLCLTCVISG DPTPEISWLK NDQPVTFLDR
YRMEVRGSEV TITIEKVNSD DSGRYGVFVK NKYGSETGQV TISVFKHGDE PKELKSM
//
