ID F6VIF4_HORSE Unreviewed; 285 AA.
AC F6VIF4;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155};
DE EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};
GN Name=LOC100050329 {ECO:0000313|Ensembl:ENSECAP00000018318.1};
OS Equus caballus (Horse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000018318.1, ECO:0000313|Proteomes:UP000002281};
RN [1] {ECO:0000313|Ensembl:ENSECAP00000018318.1, ECO:0000313|Proteomes:UP000002281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000018318.1,
RC ECO:0000313|Proteomes:UP000002281};
RX PubMed=19892987; DOI=10.1126/science.1178158;
RG Broad Institute Genome Sequencing Platform;
RG Broad Institute Whole Genome Assembly Team;
RA Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
RA Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O.,
RA Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.,
RA Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T.,
RA Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S.,
RA Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G.,
RA Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R.,
RA Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A.,
RA Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J.,
RA Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
RT "Genome sequence, comparative analysis, and population genetics of the
RT domestic horse.";
RL Science 326:865-867(2009).
RN [2] {ECO:0000313|Ensembl:ENSECAP00000018318.1}
RP IDENTIFICATION.
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000018318.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the sulfotransferase 1 family.
CC {ECO:0000256|ARBA:ARBA00005771, ECO:0000256|RuleBase:RU361155}.
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DR RefSeq; XP_001487960.2; XM_001487910.3.
DR AlphaFoldDB; F6VIF4; -.
DR SMR; F6VIF4; -.
DR STRING; 9796.ENSECAP00000018318; -.
DR PaxDb; 9796-ENSECAP00000018318; -.
DR Ensembl; ENSECAT00000022183.4; ENSECAP00000018318.1; ENSECAG00000020744.4.
DR GeneID; 100050329; -.
DR KEGG; ecb:100050329; -.
DR GeneTree; ENSGT00940000154432; -.
DR HOGENOM; CLU_027239_1_0_1; -.
DR InParanoid; F6VIF4; -.
DR OMA; CPSILIK; -.
DR OrthoDB; 3083090at2759; -.
DR TreeFam; TF321745; -.
DR Proteomes; UP000002281; Chromosome 10.
DR Bgee; ENSECAG00000020744; Expressed in liver.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0008146; F:sulfotransferase activity; IBA:GO_Central.
DR GO; GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0051923; P:sulfation; IBA:GO_Central.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000863; Sulfotransferase_dom.
DR PANTHER; PTHR11783:SF8; SULFOTRANSFERASE 2A1; 1.
DR PANTHER; PTHR11783; SULFOTRANSFERASE SULT; 1.
DR Pfam; PF00685; Sulfotransfer_1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000002281};
KW Steroid metabolism {ECO:0000256|ARBA:ARBA00023221};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU361155}.
FT DOMAIN 34..277
FT /note="Sulfotransferase"
FT /evidence="ECO:0000259|Pfam:PF00685"
SQ SEQUENCE 285 AA; 33197 MW; 34D411E4E5349E8A CRC64;
MSDGYVWFEG IPFPSMGYKP EVLREARESF ALKDEDVLIL TYPKSGTNWL IEIVCLVYSK
GDPKWIQSVP ILKRSPWVEV EYGYNLLKDK EGPRLITSHL PIQLIPKSLF NSKAKVIYLI
RNPRDVLTSG YFFFGASAFA KKPQSMEEYF GWFIKGNVPY GSWFDHTRGW MSIRGKENFL
ILSYEELKRD TRSIVEMISQ FLGKKLEPEE LNSVLKNSSF QVMKENNMSN FSLLRGQFLD
KNGILLRKGI TGDWKNHFTV AQAEAFDRIF QEKMADLPRE LFPWE
//
