ID F6VIV0_ORNAN Unreviewed; 843 AA.
AC F6VIV0;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 3.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=Protein arginine methyltransferase 9 {ECO:0000313|Ensembl:ENSOANP00000008367.3};
GN Name=PRMT9 {ECO:0000313|Ensembl:ENSOANP00000008367.3};
OS Ornithorhynchus anatinus (Duckbill platypus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Monotremata; Ornithorhynchidae; Ornithorhynchus.
OX NCBI_TaxID=9258 {ECO:0000313|Ensembl:ENSOANP00000008367.3, ECO:0000313|Proteomes:UP000002279};
RN [1] {ECO:0000313|Ensembl:ENSOANP00000008367.3, ECO:0000313|Proteomes:UP000002279}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000008367.3,
RC ECO:0000313|Proteomes:UP000002279};
RX PubMed=18464734; DOI=10.1038/nature06936;
RA Warren W.C., Hillier L.W., Marshall Graves J.A., Birney E., Ponting C.P.,
RA Grutzner F., Belov K., Miller W., Clarke L., Chinwalla A.T., Yang S.P.,
RA Heger A., Locke D.P., Miethke P., Waters P.D., Veyrunes F., Fulton L.,
RA Fulton B., Graves T., Wallis J., Puente X.S., Lopez-Otin C., Ordonez G.R.,
RA Eichler E.E., Chen L., Cheng Z., Deakin J.E., Alsop A., Thompson K.,
RA Kirby P., Papenfuss A.T., Wakefield M.J., Olender T., Lancet D.,
RA Huttley G.A., Smit A.F., Pask A., Temple-Smith P., Batzer M.A.,
RA Walker J.A., Konkel M.K., Harris R.S., Whittington C.M., Wong E.S.,
RA Gemmell N.J., Buschiazzo E., Vargas Jentzsch I.M., Merkel A., Schmitz J.,
RA Zemann A., Churakov G., Kriegs J.O., Brosius J., Murchison E.P.,
RA Sachidanandam R., Smith C., Hannon G.J., Tsend-Ayush E., McMillan D.,
RA Attenborough R., Rens W., Ferguson-Smith M., Lefevre C.M., Sharp J.A.,
RA Nicholas K.R., Ray D.A., Kube M., Reinhardt R., Pringle T.H., Taylor J.,
RA Jones R.C., Nixon B., Dacheux J.L., Niwa H., Sekita Y., Huang X., Stark A.,
RA Kheradpour P., Kellis M., Flicek P., Chen Y., Webber C., Hardison R.,
RA Nelson J., Hallsworth-Pepin K., Delehaunty K., Markovic C., Minx P.,
RA Feng Y., Kremitzki C., Mitreva M., Glasscock J., Wylie T., Wohldmann P.,
RA Thiru P., Nhan M.N., Pohl C.S., Smith S.M., Hou S., Nefedov M.,
RA de Jong P.J., Renfree M.B., Mardis E.R., Wilson R.K.;
RT "Genome analysis of the platypus reveals unique signatures of evolution.";
RL Nature 453:175-183(2008).
RN [2] {ECO:0000313|Ensembl:ENSOANP00000008367.3}
RP IDENTIFICATION.
RC STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000008367.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F6VIV0; -.
DR STRING; 9258.ENSOANP00000008367; -.
DR Ensembl; ENSOANT00000008369.3; ENSOANP00000008367.3; ENSOANG00000005264.4.
DR eggNOG; KOG1501; Eukaryota.
DR GeneTree; ENSGT00940000158472; -.
DR InParanoid; F6VIV0; -.
DR OMA; NILEPFY; -.
DR TreeFam; TF315221; -.
DR Proteomes; UP000002279; Chromosome 12.
DR Bgee; ENSOANG00000005264; Expressed in ovary and 7 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0035241; F:protein-arginine omega-N monomethyltransferase activity; IBA:GO_Central.
DR GO; GO:0035243; F:protein-arginine omega-N symmetric methyltransferase activity; IEA:Ensembl.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006397; P:mRNA processing; IEA:Ensembl.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 2.70.160.11; Hnrnp arginine n-methyltransferase1; 2.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR025799; Arg_MeTrfase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR11006; PROTEIN ARGININE N-METHYLTRANSFERASE; 1.
DR Pfam; PF06325; PrmA; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 2.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS51678; SAM_MT_PRMT; 2.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|PROSITE-ProRule:PRU01015};
KW Reference proteome {ECO:0000313|Proteomes:UP000002279};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU01015};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW Transferase {ECO:0000256|PROSITE-ProRule:PRU01015}.
FT REPEAT 98..131
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 544..578
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 843 AA; 94159 MW; CA04D2C69E54E49E CRC64;
MWDLIISHLP QSLAQCLVRI RCLPNTTMII KHLVQFPVCN RYSVNTVDRL IFLNYLNFFK
ETFQYTLFRW AEELDALSRI PDLFGCYEQA LELFPDDEVI CNSMGEHLFR MGFRDEAAGY
FHKAVKLNPD FADAKENFYR VANWLVERWH FIMLNDIKRN MAYQAAIQKV VSLGCKTVLD
IGTGTGILSM FAKKAGAPSV YACELSKTMY ELACDVVAAN NMATEIKLLH MKSLDIEVPK
HLPERVSLVV TETVDAGLFG EGIVESLIHA WENLLLKPKP KGQFGNCEEY GQVIPAGAAV
FGMAVECAEI RRHHRVGVQD VAGIHLPETL QFRSPAHSSG DSEEAIEPYT TEKMSRVPGG
YLPLTKSFEA LTVDFNNLQE LKSLVIKKPV KINVPVTRAG VLDAIVIWFV LQLDDEHSLS
TSPSEETCWE QAVYPVQDLP DYSVRPGDQV VMEVSCQDCY LRIQNIHILN SEKMMDVERS
SSESGTLPLG NEAELCNALA SLQTSKSDAL GQKCTLESTE IALLNNRPYH EAFKAAMDKV
LSSLTPDRSS QPMDVEGRGG EVTSGGDQNP NSPRATPEPL FVLDVSEGFS ILPLIAGRLG
LVKAYSSVEK EQHRVALDLI SEANRFPRET LEFWLSHVED ECAVLQRPKS DKLWSIIILD
VIETSGLIQQ EVMEKAAISR CLLQSGGKIF PQHVLVMGML VESQTLVEES AVQGTEPTLG
LNIAPFINQF QVPVRVFLDL STLPCVPLSK PVELLRLDLM NPYLNSSNRE VKVQISKSGQ
VTAIPFWYHI CLDEEIKLDT SCESSHWKQA AVVLDNPIPV QVGEELELSI QHHKSNVSIT
VKQ
//
