ID F6VIZ8_XENTR Unreviewed; 555 AA.
AC F6VIZ8; F6QJX3;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 5.
DT 24-JAN-2024, entry version 66.
DE SubName: Full=Uncharacterized XB5944457 {ECO:0000313|Ensembl:ENSXETP00000035505};
GN Name=XB5944457 [provisional] {ECO:0000313|Ensembl:ENSXETP00000035505};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|Ensembl:ENSXETP00000035505};
RN [1] {ECO:0000313|Ensembl:ENSXETP00000035505}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000035505};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [2] {ECO:0000313|Ensembl:ENSXETP00000035505}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUN-2011) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; F6VIZ8; -.
DR Ensembl; ENSXETT00000035505; ENSXETP00000035505; ENSXETG00000012105.
DR Xenbase; XB-GENE-5944458; XB5944457 [provisional].
DR HOGENOM; CLU_006855_9_5_1; -.
DR Bgee; ENSXETG00000012105; Expressed in brain and 7 other cell types or tissues.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005332; F:gamma-aminobutyric acid:sodium:chloride symporter activity; IEA:InterPro.
DR GO; GO:0006836; P:neurotransmitter transport; IEA:InterPro.
DR InterPro; IPR000175; Na/ntran_symport.
DR InterPro; IPR002980; Na/ntran_symport_GABA_GAT1.
DR InterPro; IPR037272; SNS_sf.
DR PANTHER; PTHR11616:SF138; SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER 1; 1.
DR PANTHER; PTHR11616; SODIUM/CHLORIDE DEPENDENT TRANSPORTER; 1.
DR Pfam; PF00209; SNF; 1.
DR PRINTS; PR01195; GAT1TRNSPORT.
DR PRINTS; PR00176; NANEUSMPORT.
DR SUPFAM; SSF161070; SNF-like; 1.
DR PROSITE; PS00754; NA_NEUROTRAN_SYMP_2; 1.
DR PROSITE; PS50267; NA_NEUROTRAN_SYMP_3; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 53..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 83..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 205..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 277..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..357
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 378..403
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 409..433
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 454..473
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 493..513
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 536..555
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 555 AA; 62506 MW; E1295527168429CE CRC64;
MATNGTKVAD GQISTEVSEA PVTNDKPKTL VVKVQKKKTE EVERDTWKGR FDFLMSCVGY
AIGLGNVWRF PYLCGKNGGG VGLAAAVLSF WLNIYYIVII AWAIYYLYNS FTTTLPWKHC
DNSWNTERCF SNYSIANTTN MTSAVVEFWE RNMHQMTDGL EKPGQIRWPL AITLAIAWVL
VYFCIWKGVG WTGKVVYFSA TYPYIMLVIL FFRGVTLPGA LDGILFYITP KFSKLSDSEV
WLDAATQIFF SYGLGLGSLI ALGSYNRFHN NVYRDSIIVC CINSCTSMFA GFVIFSIVGF
MAHVTKRPIE QVAASGPGLA FLAYPEAVTQ LPISPLWAVL FFSMLLMLGI DSQFCTVEGF
ITALVDEFPK LLRTRREIFI AVVCVVSYLV GLSNITQGGI YVFKLFDYYS ASGMSLLFLV
FFECISISWC YGVNRFYDNI EEMVGYRPCI WWKLCWSFFT PIIVAGVFLF SAVQMTPLTM
GSYVFPSWGQ GVGWFMALSS MVLIPGYMVY LFLSLKGSLK QRLQVMIQPT EEVVRSENGP
EQLSQSNSAN KEAYI
//
