ID F6VMF6_CALJA Unreviewed; 516 AA.
AC F6VMF6;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 3.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Solute carrier family 9 member B1 {ECO:0000313|Ensembl:ENSCJAP00000028659.4};
GN Name=SLC9B1 {ECO:0000313|Ensembl:ENSCJAP00000028659.4};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000028659.4, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000028659.4}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000028659.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the monovalent cation:proton antiporter 1 (CPA1)
CC transporter (TC 2.A.36) family. {ECO:0000256|ARBA:ARBA00007367}.
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DR AlphaFoldDB; F6VMF6; -.
DR STRING; 9483.ENSCJAP00000028659; -.
DR Ensembl; ENSCJAT00000030284.5; ENSCJAP00000028659.4; ENSCJAG00000015534.6.
DR eggNOG; KOG3826; Eukaryota.
DR GeneTree; ENSGT00390000013285; -.
DR HOGENOM; CLU_018415_4_1_1; -.
DR InParanoid; F6VMF6; -.
DR OMA; ICVATMS; -.
DR TreeFam; TF319087; -.
DR Proteomes; UP000008225; Chromosome 3.
DR Bgee; ENSCJAG00000015534; Expressed in liver and 3 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR PANTHER; PTHR31102; -; 1.
DR PANTHER; PTHR31102:SF5; SLC9B1-LIKE PROTEIN SLC9B1P1-RELATED; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 63..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 91..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 124..143
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 213..236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..280
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 286..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 339..356
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 368..386
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 398..419
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 431..452
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 472..491
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 101..482
FT /note="Cation/H+ exchanger"
FT /evidence="ECO:0000259|Pfam:PF00999"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 13..30
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 516 AA; 56112 MW; 764484592226F097 CRC64;
MYTTESKSEY LEDENFQTST NPQSLIDPNS IAHGETKTVL SDTEETKPQR KEKTYSSCPL
RGVLNVIITN GVILIMIWCL TWSILGSEAL PGGNLFGLLI IFYSAIIGGK FLELIRIPLV
PPLPPLLGML LAGFMIRNVP FISKHIHVDS TLSSVIRNIA LTVILIRAGL GLDPQALKHL
KEVCFRLAAG PCLIEASAAA VFSHFIMKFP WQWAFLLGFV LGAVSPAVVV PSMLLLQENG
YGIKKGIPTL LMAASSMDDI LAITGFNTCL SIVFSTGSIV HNILYSIRNV CVSLLAGTVL
GFFLRYFPSE DQEELSLKRG FLVLTMCVSA VLGSQRIGLL GSGGLCTLVL SFIAGTKWSQ
EKMKVQKIIT NVWDIFQPLL FGLVGAEVSV SSLESNTVGI SVATVSLALC VRMFTTYLLM
CFAGFSFKEK IFIACAWMPK ATVQAVLGPL ALETARISAP HLESYSKDVM TVAFLAILIT
APNGALLIGI LGPKMLTRHY DTSEIKKLQL STLEHN
//
