ID F6VRH2_ORNAN Unreviewed; 696 AA.
AC F6VRH2;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 2.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=SEC14 and spectrin domain containing 1 {ECO:0000313|Ensembl:ENSOANP00000013780.3};
GN Name=SESTD1 {ECO:0000313|Ensembl:ENSOANP00000013780.3};
OS Ornithorhynchus anatinus (Duckbill platypus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Monotremata; Ornithorhynchidae; Ornithorhynchus.
OX NCBI_TaxID=9258 {ECO:0000313|Ensembl:ENSOANP00000013780.3, ECO:0000313|Proteomes:UP000002279};
RN [1] {ECO:0000313|Ensembl:ENSOANP00000013780.3}
RP IDENTIFICATION.
RC STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000013780.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SOLO family.
CC {ECO:0000256|ARBA:ARBA00038285}.
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DR RefSeq; XP_001515483.1; XM_001515433.2.
DR RefSeq; XP_007669475.1; XM_007671285.1.
DR AlphaFoldDB; F6VRH2; -.
DR STRING; 9258.ENSOANP00000013780; -.
DR Ensembl; ENSOANT00000013783.4; ENSOANP00000013780.3; ENSOANG00000008646.4.
DR GeneID; 100085094; -.
DR KEGG; oaa:100085094; -.
DR CTD; 91404; -.
DR eggNOG; KOG4240; Eukaryota.
DR GeneTree; ENSGT00730000111148; -.
DR HOGENOM; CLU_010440_1_0_1; -.
DR InParanoid; F6VRH2; -.
DR OMA; PDAFWDK; -.
DR OrthoDB; 2878608at2759; -.
DR TreeFam; TF332003; -.
DR Proteomes; UP000002279; Unplaced.
DR Bgee; ENSOANG00000008646; Expressed in brain and 8 other cell types or tissues.
DR GO; GO:0034704; C:calcium channel complex; IEA:Ensembl.
DR GO; GO:0045111; C:intermediate filament cytoskeleton; IEA:Ensembl.
DR GO; GO:0070300; F:phosphatidic acid binding; IEA:Ensembl.
DR GO; GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IBA:GO_Central.
DR GO; GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IBA:GO_Central.
DR GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IBA:GO_Central.
DR GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IBA:GO_Central.
DR GO; GO:0070273; F:phosphatidylinositol-4-phosphate binding; IBA:GO_Central.
DR GO; GO:0010314; F:phosphatidylinositol-5-phosphate binding; IBA:GO_Central.
DR GO; GO:1904878; P:negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel; IEA:Ensembl.
DR Gene3D; 1.20.58.60; -; 2.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR PANTHER; PTHR46607; SEC14 DOMAIN AND SPECTRIN REPEAT-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR46607:SF1; SEC14 DOMAIN AND SPECTRIN REPEAT-CONTAINING PROTEIN 1; 1.
DR Pfam; PF13716; CRAL_TRIO_2; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 1.
DR PROSITE; PS50191; CRAL_TRIO; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002279};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1..153
FT /note="CRAL-TRIO"
FT /evidence="ECO:0000259|PROSITE:PS50191"
SQ SEQUENCE 696 AA; 79474 MW; AD0C986190ADCF61 CRC64;
MEATIILPIL KKKLAFLSGG KDRRSGLILT IPLCLEQTNM EELSVTLDYL LSIPSEKCKA
RGFTVIVDGR KSQWNVVKTV VLMLQNVVPA EVSLVCVVKP DEFWDKKVTH FCFWKEKDRL
GFEVILVSAN KLTRYIEPCQ LTEDFGGSLT YDHMDWLNKR LVFEKFTKES TSLLDELALI
NNGSDKGNQQ EKERSMDLNF LPSVDPETVL QTGHELLSEL QQRRFNGSDG GVSWSPMDDE
LLAQPQVMKL LDSLREQYTR YQEVCRQRSK RTQLEEIQQK VMQVVNWLEG PGSEQLRTQW
GIGDSIRASQ ALQQKHEEIE SQHSEWFAVY VELNQQIAAL LNAGDEEDLV ELKSLQQQLS
DVCYRQASQL EFRQNLLQAA LEFHGVAQDL SQQLDGLLGM LCVDVAPADG ASIQQTLKLL
EEKLKSVDIG LQGLREKGQS LLDQISNQAS WAYGKDVTIE NKENVDHIQG VMEDMQLRKQ
RCEDMVDVRR LKMLQMVQLF KCEEDAAQAV EWLSELLDAL LKTHIRLGDD AQETKVLLEK
HRKFVDVAQS TYDYGRQLLQ ATVVLCQSLR CTSRSSGDTL PRLNRVWKQF TIASEERVHR
LEMTIAFHST AEKILQECPE QPEAIHDEEQ FDEIEAVGKS LLDRLTVPVV YPDGNEQYFG
SPSDMASTAE HIRERMKLVS LKRQQLRQPE AASIDS
//
