ID F6W8P4_MOUSE Unreviewed; 151 AA.
AC F6W8P4;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=EGF-like domain 7 {ECO:0000313|Ensembl:ENSMUSP00000118924.4};
DE Flags: Fragment;
GN Name=Egfl7 {ECO:0000313|Ensembl:ENSMUSP00000118924.4,
GN ECO:0000313|MGI:MGI:2449923};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000118924.4, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000118924.4, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000118924.4,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000118924.4}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000118924.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR AlphaFoldDB; F6W8P4; -.
DR SMR; F6W8P4; -.
DR MaxQB; F6W8P4; -.
DR ProteomicsDB; 357399; -.
DR Antibodypedia; 32209; 412 antibodies from 37 providers.
DR Ensembl; ENSMUST00000145575.10; ENSMUSP00000118924.4; ENSMUSG00000026921.21.
DR AGR; MGI:2449923; -.
DR MGI; MGI:2449923; Egfl7.
DR VEuPathDB; HostDB:ENSMUSG00000026921; -.
DR GeneTree; ENSGT00940000160015; -.
DR HOGENOM; CLU_083642_1_0_1; -.
DR OMA; PGWRRVH; -.
DR ChiTaRS; Egfl7; mouse.
DR Proteomes; UP000000589; Chromosome 2.
DR Bgee; ENSMUSG00000026921; Expressed in lung and 87 other cell types or tissues.
DR ExpressionAtlas; F6W8P4; baseline and differential.
DR CDD; cd00054; EGF_CA; 1.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR013111; EGF_extracell.
DR InterPro; IPR011489; EMI_domain.
DR PANTHER; PTHR14949; EGF-LIKE-DOMAIN, MULTIPLE 7, 8; 1.
DR PANTHER; PTHR14949:SF21; EPIDERMAL GROWTH FACTOR-LIKE PROTEIN 7; 1.
DR Pfam; PF07974; EGF_2; 1.
DR Pfam; PF07546; EMI; 1.
DR SMART; SM00181; EGF; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 1.
DR PROSITE; PS51041; EMI; 1.
PE 1: Evidence at protein level;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Proteomics identification {ECO:0007829|MaxQB:F6W8P4};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..151
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5023912226"
FT DOMAIN 28..105
FT /note="EMI"
FT /evidence="ECO:0000259|PROSITE:PS51041"
FT DOMAIN 104..136
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 108..118
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 126..135
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 151
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000118924.4"
SQ SEQUENCE 151 AA; 16245 MW; 2B829A20FD591A98 CRC64;
MWGSGELLVA WFLVLAADGT TEHVYRPSRR VCTVGISGGS ISETFVQRVY QPYLTTCDGH
RACSTYRTIY RTAYRRSPGV TPARPRYACC PGWKRTSGLP GACGAAICQP PCGNGGSCIR
PGHCRCPVGW QGDTCQTDVD ECSTGEASCP Q
//
