ID F6WBA5_MACMU Unreviewed; 541 AA.
AC F6WBA5;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=NEDD4 binding protein 3 {ECO:0000313|Ensembl:ENSMMUP00000023172.2};
GN Name=N4BP3 {ECO:0000313|Ensembl:ENSMMUP00000023172.2,
GN ECO:0000313|VGNC:VGNC:75053};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|Ensembl:ENSMMUP00000023172.2, ECO:0000313|Proteomes:UP000006718};
RN [1] {ECO:0000313|Proteomes:UP000006718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=17573 {ECO:0000313|Proteomes:UP000006718};
RX PubMed=17431167; DOI=10.1126/science.1139247;
RA Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M.,
RA Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C., Wilson R.K.,
RA Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W., Hardison R.C.,
RA Makova K.D., Miller W., Milosavljevic A., Palermo R.E., Siepel A.,
RA Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J.,
RA Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y., Dinh H.H.,
RA Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T., Godfrey J.,
RA Hawes A.C., Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N.,
RA Joshi V., Khan Z.M., Kirkness E.F., Cree A., Fowler R.G., Lee S.,
RA Lewis L.R., Li Z., Liu Y.-S., Moore S.M., Muzny D., Nazareth L.V.,
RA Ngo D.N., Okwuonu G.O., Pai G., Parker D., Paul H.A., Pfannkoch C.,
RA Pohl C.S., Rogers Y.-H.C., Ruiz S.J., Sabo A., Santibanez J.,
RA Schneider B.W., Smith S.M., Sodergren E., Svatek A.F., Utterback T.R.,
RA Vattathil S., Warren W., White C.S., Chinwalla A.T., Feng Y., Halpern A.L.,
RA Hillier L.W., Huang X., Minx P., Nelson J.O., Pepin K.H., Qin X.,
RA Sutton G.G., Venter E., Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P.,
RA Jones S.M., Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L.,
RA Csuros M., Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H.,
RA Liu Y., Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E.,
RA Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J.,
RA Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J.,
RA Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A.,
RA Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J., Denby A.,
RA Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A., Marklein A.,
RA Nielsen R., Vallender E.J., Clark A.G., Ferguson B., Hernandez R.D.,
RA Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S., Pu L.-L., Ren Y.,
RA Smith D.G., Wheeler D.A., Schenck I., Ball E.V., Chen R., Cooper D.N.,
RA Giardine B., Hsu F., Kent W.J., Lesk A., Nelson D.L., O'brien W.E.,
RA Pruefer K., Stenson P.D., Wallace J.C., Ke H., Liu X.-M., Wang P.,
RA Xiang A.P., Yang F., Barber G.P., Haussler D., Karolchik D., Kern A.D.,
RA Kuhn R.M., Smith K.E., Zwieg A.S.;
RT "Evolutionary and biomedical insights from the rhesus macaque genome.";
RL Science 316:222-234(2007).
RN [2] {ECO:0000313|Ensembl:ENSMMUP00000023172.2}
RP IDENTIFICATION.
RC STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000023172.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell projection, dendrite
CC {ECO:0000256|ARBA:ARBA00004279}. Vesicle
CC {ECO:0000256|ARBA:ARBA00004373}.
CC -!- SIMILARITY: Belongs to the N4BP3 family.
CC {ECO:0000256|ARBA:ARBA00010640}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_001093839.1; XM_001093839.3.
DR AlphaFoldDB; F6WBA5; -.
DR STRING; 9544.ENSMMUP00000023172; -.
DR PaxDb; 9544-ENSMMUP00000023172; -.
DR Ensembl; ENSMMUT00000024759.4; ENSMMUP00000023172.2; ENSMMUG00000017607.4.
DR GeneID; 701704; -.
DR KEGG; mcc:701704; -.
DR CTD; 23138; -.
DR VEuPathDB; HostDB:ENSMMUG00000017607; -.
DR VGNC; VGNC:75053; N4BP3.
DR eggNOG; ENOG502QVNK; Eukaryota.
DR GeneTree; ENSGT00940000158603; -.
DR HOGENOM; CLU_026379_3_1_1; -.
DR InParanoid; F6WBA5; -.
DR OMA; EFSCPTT; -.
DR OrthoDB; 5394101at2759; -.
DR TreeFam; TF331420; -.
DR Proteomes; UP000006718; Chromosome 6.
DR Bgee; ENSMMUG00000017607; Expressed in dorsolateral prefrontal cortex and 15 other cell types or tissues.
DR GO; GO:0042995; C:cell projection; IEA:UniProtKB-KW.
DR GO; GO:0031410; C:cytoplasmic vesicle; IBA:GO_Central.
DR GO; GO:0045087; P:innate immune response; IEA:Ensembl.
DR InterPro; IPR033571; N4BP3.
DR PANTHER; PTHR32274; NEDD4-BINDING PROTEIN 3; 1.
DR PANTHER; PTHR32274:SF1; NEDD4-BINDING PROTEIN 3; 1.
DR Pfam; PF06818; Fez1; 2.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Reference proteome {ECO:0000313|Proteomes:UP000006718}.
FT REGION 174..238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 332..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 427..461
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 183..213
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 541 AA; 60037 MW; 7805104D4DF497A9 CRC64;
MATAPGPAGI AMGSVGSLLE RHDLSPEELR AALAGSQGSR QPDGLLRKGL GHRELFSYLH
FPKKDGKSTK RAPRNEPADY ATLYYREHPR AGDFSKTSLP ERGRFDKCRI RPSVFKPTAG
NGKGFLSMQS LAVHKGQKLW RSNGSLHTLA CHPPLSPGPQ ASQARAQLLH ALSLDEGGPE
PEPSLSDSSS GGSFGRSPGT GPGPFSSSLG HLNHLGGSLD RASRGPKEAG PQAVLSCLPE
PPPPYEFSCS SAEEMGAVLP EACEELKRGL GNEDGSNPFT QVLEERQRLW LAELKRLYVE
RLHEVTQKAE RSERNLQLQL FMAQQEQRRL RKELRAQQGL APEPRAPGTL SEADPSARPE
EEARWEVCQK TAEISLLKQQ LREAQAELAQ KLAEIFSLKT QLRGSRAQAQ AQDAELVRLR
QAVRSLQEQA PREEAPGSCE TDDCKSRGLL GEAGGSEARD GAEQLRAELL QERLRGQEQA
LRFEQERRTW QEEKERVLRY QREIQGGYMD MYRRNQALEQ ELRALREPPT PWSPRLESSK
I
//
