ID F6WDZ9_XENTR Unreviewed; 1148 AA.
AC F6WDZ9;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 4.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=Myosin-binding protein C, fast-type isoform X3 {ECO:0000313|RefSeq:XP_031761653.1};
DE SubName: Full=Myosin-binding protein C, fast-type-like {ECO:0000313|Ensembl:ENSXETP00000007358};
GN Name=mybpc2 {ECO:0000313|RefSeq:XP_031761653.1,
GN ECO:0000313|Xenbase:XB-GENE-923190};
GN Synonyms=XB5889096 [provisional]
GN {ECO:0000313|Ensembl:ENSXETP00000007358};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|Ensembl:ENSXETP00000007358};
RN [1] {ECO:0000313|Ensembl:ENSXETP00000007358}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000007358};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [2] {ECO:0000313|Ensembl:ENSXETP00000007358}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUN-2011) to UniProtKB.
RN [3] {ECO:0000313|RefSeq:XP_031761653.1}
RP IDENTIFICATION.
RC STRAIN=Nigerian {ECO:0000313|RefSeq:XP_031761653.1};
RC TISSUE=Liver and blood {ECO:0000313|RefSeq:XP_031761653.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_031761653.1; XM_031905793.1.
DR Ensembl; ENSXETT00000007358; ENSXETP00000007358; ENSXETG00000003393.
DR Xenbase; XB-GENE-923190; mybpc2.
DR Xenbase; XB-GENE-5889097; XB5889096 [provisional].
DR eggNOG; ENOG502QW17; Eukaryota.
DR HOGENOM; CLU_006405_1_1_1; -.
DR OMA; KNTACIL; -.
DR TreeFam; TF351819; -.
DR Reactome; R-XTR-390522; Striated Muscle Contraction.
DR Proteomes; UP000008143; Chromosome 7.
DR Bgee; ENSXETG00000003393; Expressed in skeletal muscle tissue and 7 other cell types or tissues.
DR CDD; cd00063; FN3; 3.
DR CDD; cd00096; Ig; 1.
DR CDD; cd05894; Ig_C5_MyBP-C; 1.
DR CDD; cd05748; Ig_Titin_like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 10.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR040849; MyBP-C_THB.
DR PANTHER; PTHR13817:SF17; MYOSIN-BINDING PROTEIN C, FAST-TYPE; 1.
DR PANTHER; PTHR13817; TITIN; 1.
DR Pfam; PF00041; fn3; 3.
DR Pfam; PF07679; I-set; 6.
DR Pfam; PF18362; THB; 1.
DR Pfam; PF07686; V-set; 1.
DR PRINTS; PR00014; FNTYPEIII.
DR SMART; SM00060; FN3; 3.
DR SMART; SM00409; IG; 7.
DR SMART; SM00408; IGc2; 6.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 7.
DR PROSITE; PS50853; FN3; 3.
DR PROSITE; PS50835; IG_LIKE; 6.
PE 4: Predicted;
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Reference proteome {ECO:0000313|Proteomes:UP000008143};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 56..160
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 274..339
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 353..447
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 546..639
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 648..744
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 746..841
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 845..933
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 941..1037
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1055..1139
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 1..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 25..39
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1148 AA; 128914 MW; AE8BDC91C06C811C CRC64;
MPEPAKAAGK KGVAAPKQAA KPAAKEAPAP PPPEAPQDAL DGELPPDDTN PEDRTPELTG
LFIIKPDNVT IEAGKDIVLL ASVDSSQLTV KPNIKWFKGK WLELGAKSGA RFQFKETFDK
EKKVYNFELR INKATVADNG GYRCEVISKD KCDSSMFNIE VEAAGKEDGN LLHSFKRVGG
EGKKDEDAGE LDFSGLLKKR VEDKQKEQKK KKDDDDCGIP PDVWELLKNA KPSDFERIAF
EHGITDLRGM LKRLKKVKKE VKKSEAFGKK LDPCYSVDKG NKIKMQVEVT NPDVQIKWFK
NGQEIKPSAK FVFENIGLRR VLTINKCTLA DDAAYECIIG DEKCYTELFV KEPPVLITKP
LDDTQAFVGD KVELEVEVSE EGAQVIWMKD GTELTREETF KYRFKKDGKK HILIINEATL
EDTGRYQVMT NGGKCEADLQ VEEKQLEVLQ GIADLTVKAT DQAVFKCEVS DEKVTGKWYK
NGVEIKPSKR ITMTHKGRIH KLVIDDVRPE DEADYTFIPD GYALTLSAKL NFLEIKIVYV
PKQEPPRIHL DCSGGQHVNT IVVVAGNKLR FDVPITGEPA PTVAWFRGNA EFNELEGRVH
VEIRNEMSSF IIEGAERADE GSYNIVVTNP VGEDKATLIV KVVDVPDPPE NVRITSVGED
WAHVIWDPPL YDGGQAVTGY LIERKKKGSQ RWMKMNFEVF TGTEYESVKM IEGVLYEIRV
FAVNTIGISQ QANTSKPFMP IAPTSEPLHM TVEDVTDTTC TLKWRPPDRI GAGGIDGYLI
EYCREGSDEW IPSNKEPVER CGFTVKDLPT GEKVSFRVRA VNIAGLSEPA VLAQPVTIRE
IVQQPKIRLP RHLRQTFIKK VGEQVNLVIP FQGKPRPVVT WAKEDKPLDP KQVSIRTSEV
DSILFIRSAE RAHSGKYVLS VKIENMEDSA SINIRIVEKP GPAQVVTVKE VWGFNTLLEW
QPPKDNGNSE ITGYTIQKAD KKTMEWFTVY EHNRQTRCTI SDLIMGNEYY FRVYSENICG
LSETPGVSKN TAYIQKTGLV YKPVDYKEHD YSFAPKFLTP LIDRTVVAGY STALNCAVRG
HPKPKVIWMK NKVEIRDDPK FLMKHNQGVL TLNIRKPSPF DGGTYTCKAV NELGEAEVVC
KLEVRVPQ
//
