ID F6WFD9_CIOIN Unreviewed; 338 AA.
AC F6WFD9; A0A1W2WLG4;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Folate receptor gamma {ECO:0000313|Ensembl:ENSCINP00000012310.3};
GN Name=LOC100178291 {ECO:0000313|Ensembl:ENSCINP00000012310.3};
OS Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis).
OC Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
OC Cionidae; Ciona.
OX NCBI_TaxID=7719 {ECO:0000313|Ensembl:ENSCINP00000012310.3, ECO:0000313|Proteomes:UP000008144};
RN [1] {ECO:0000313|Proteomes:UP000008144}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12481130; DOI=10.1126/science.1080049;
RA Dehal P., Satou Y., Campbell R.K., Chapman J., Degnan B., De Tomaso A.,
RA Davidson B., Di Gregorio A., Gelpke M., Goodstein D.M., Harafuji N.,
RA Hastings K.E., Ho I., Hotta K., Huang W., Kawashima T., Lemaire P.,
RA Martinez D., Meinertzhagen I.A., Necula S., Nonaka M., Putnam N., Rash S.,
RA Saiga H., Satake M., Terry A., Yamada L., Wang H.G., Awazu S., Azumi K.,
RA Boore J., Branno M., Chin-Bow S., DeSantis R., Doyle S., Francino P.,
RA Keys D.N., Haga S., Hayashi H., Hino K., Imai K.S., Inaba K., Kano S.,
RA Kobayashi K., Kobayashi M., Lee B.I., Makabe K.W., Manohar C., Matassi G.,
RA Medina M., Mochizuki Y., Mount S., Morishita T., Miura S., Nakayama A.,
RA Nishizaka S., Nomoto H., Ohta F., Oishi K., Rigoutsos I., Sano M.,
RA Sasaki A., Sasakura Y., Shoguchi E., Shin-i T., Spagnuolo A., Stainier D.,
RA Suzuki M.M., Tassy O., Takatori N., Tokuoka M., Yagi K., Yoshizaki F.,
RA Wada S., Zhang C., Hyatt P.D., Larimer F., Detter C., Doggett N.,
RA Glavina T., Hawkins T., Richardson P., Lucas S., Kohara Y., Levine M.,
RA Satoh N., Rokhsar D.S.;
RT "The draft genome of Ciona intestinalis: insights into chordate and
RT vertebrate origins.";
RL Science 298:2157-2167(2002).
RN [2] {ECO:0000313|Ensembl:ENSCINP00000012310.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the folate receptor family.
CC {ECO:0000256|ARBA:ARBA00007932}.
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DR EMBL; EAAA01001447; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_002130677.1; XM_002130641.3.
DR AlphaFoldDB; F6WFD9; -.
DR STRING; 7719.ENSCINP00000012310; -.
DR Ensembl; ENSCINT00000012310.3; ENSCINP00000012310.3; ENSCING00000005953.3.
DR GeneID; 100178291; -.
DR KEGG; cin:100178291; -.
DR GeneTree; ENSGT00950000183144; -.
DR HOGENOM; CLU_070826_0_0_1; -.
DR InParanoid; F6WFD9; -.
DR OMA; VAYHYAL; -.
DR OrthoDB; 2896461at2759; -.
DR TreeFam; TF328532; -.
DR Proteomes; UP000008144; Chromosome 2.
DR GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
DR GO; GO:0038023; F:signaling receptor activity; IBA:GO_Central.
DR InterPro; IPR004269; Folate_rcpt.
DR InterPro; IPR018143; Folate_rcpt-like.
DR PANTHER; PTHR10517; FOLATE RECEPTOR; 1.
DR PANTHER; PTHR10517:SF14; FOLATE_REC DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF03024; Folate_rec; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008144};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..338
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014090293"
FT TRANSMEM 253..275
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 35..206
FT /note="Folate receptor-like"
FT /evidence="ECO:0000259|Pfam:PF03024"
FT REGION 319..338
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 338 AA; 38675 MW; 887DF7AB7CBFD85D CRC64;
MFTVRLSSMF VLLCFLYTCV LVDGSDKKET DVLNTCLSSK HHKTQPGPED NLFKCSAWLN
NSCCTNYTAQ YVHGDGQPLY NLNFSHCAPM SDKCRNHFTN NNCFYECSPY LGPWITPQKL
SYRHERMYKV PLCASQCNAW WQDCKDESTC VENWSTGFKW DKSGNHCPRN TVCRPFTSVY
HNASHFCETV WGPDDFVVTP DHNYCMKLSF TGPNPNVEVA YHYALKKHLI KGTAVPPYSE
PPKIPPLQVQ GTIFSVVIGS IIIIVVIALL IFVGLKRYRG TLFHHQGVPM RFRNLLRSSR
QSAMVTRSDP GAEMSFMQYE EEEEEDNPEM NGSLRLDL
//
