ID F6WIC2_XENTR Unreviewed; 289 AA.
AC F6WIC2;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 4.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Coiled-coil and C2 domain containing 2A {ECO:0000313|Ensembl:ENSXETP00000043844};
DE SubName: Full=Complement C1q tumor necrosis factor-related protein 7 {ECO:0000313|RefSeq:XP_017946491.1};
GN Name=c1qtnf7 {ECO:0000313|RefSeq:XP_017946491.1,
GN ECO:0000313|Xenbase:XB-GENE-22068086};
GN Synonyms=cc2d2a {ECO:0000313|Ensembl:ENSXETP00000043844};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|Ensembl:ENSXETP00000043844};
RN [1] {ECO:0000313|Ensembl:ENSXETP00000043844}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000043844};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [2] {ECO:0000313|Ensembl:ENSXETP00000043844}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUN-2011) to UniProtKB.
RN [3] {ECO:0000313|RefSeq:XP_017946491.1}
RP IDENTIFICATION.
RC STRAIN=Nigerian {ECO:0000313|RefSeq:XP_017946491.1};
RC TISSUE=Liver and blood {ECO:0000313|RefSeq:XP_017946491.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_017946491.1; XM_018091002.2.
DR Ensembl; ENSXETT00000043844; ENSXETP00000043844; ENSXETG00000020325.
DR GeneID; 100492671; -.
DR KEGG; xtr:100492671; -.
DR AGR; Xenbase:XB-GENE-5909177; -.
DR CTD; 114905; -.
DR Xenbase; XB-GENE-22068086; c1qtnf7.
DR Xenbase; XB-GENE-5909177; cc2d2a.
DR eggNOG; ENOG502R68F; Eukaryota.
DR HOGENOM; CLU_001074_0_3_1; -.
DR OMA; CKCGSLL; -.
DR TreeFam; TF329591; -.
DR Proteomes; UP000008143; Chromosome 1.
DR Bgee; ENSXETG00000020325; Expressed in mesonephros.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.40; -; 1.
DR InterPro; IPR001073; C1q_dom.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR PANTHER; PTHR15427:SF24; COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 7; 1.
DR PANTHER; PTHR15427; EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER; 1.
DR Pfam; PF00386; C1q; 1.
DR Pfam; PF01391; Collagen; 2.
DR PRINTS; PR00007; COMPLEMNTC1Q.
DR SMART; SM00110; C1Q; 1.
DR SUPFAM; SSF49842; TNF-like; 1.
DR PROSITE; PS50871; C1Q; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008143};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..289
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041157379"
FT DOMAIN 144..280
FT /note="C1q"
FT /evidence="ECO:0000259|PROSITE:PS50871"
FT REGION 37..136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 61..80
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 289 AA; 31151 MW; 2A1CB4F109077F15 CRC64;
MMLILLYVIS FAFCATGQPF NNKLKGDPQY TRYVCSIPGL PGPPGSPGRN GQTGPHGRIG
LPGRDGRDGR KGEKGEKGTA GLRGKTGPLG PTGDRGDQGE MGKKGPVGEA GDNGELGPKG
PLGPRGPKGE RGERGEPGIC KCGNIILKSA FSVGITTSYP QERLPILFNK ILFNEGEHYN
PSVGKFICAI PGIYYFSYDI TLANKHLAIS LVHNGQYKIK TFDANTGNHD VASGSTLVYL
KPEDEVWLEI FYTDQNGLFS DPSWADSLFS GFLLYADTDY MNALSEDYF
//
