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Database: UniProt
Entry: F6WTY3_ORNAN
LinkDB: F6WTY3_ORNAN
Original site: F6WTY3_ORNAN 
ID   F6WTY3_ORNAN            Unreviewed;       496 AA.
AC   F6WTY3;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   27-JUL-2011, sequence version 1.
DT   16-OCT-2019, entry version 59.
DE   SubName: Full=Potassium voltage-gated channel subfamily J member 3 {ECO:0000313|Ensembl:ENSOANP00000009762};
GN   Name=KCNJ3 {ECO:0000313|Ensembl:ENSOANP00000009762};
OS   Ornithorhynchus anatinus (Duckbill platypus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus.
OX   NCBI_TaxID=9258 {ECO:0000313|Ensembl:ENSOANP00000009762, ECO:0000313|Proteomes:UP000002279};
RN   [1] {ECO:0000313|Ensembl:ENSOANP00000009762}
RP   IDENTIFICATION.
RC   STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000009762};
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   RefSeq; XP_001508825.1; XM_001508775.3.
DR   STRING; 9258.ENSOANP00000009762; -.
DR   Ensembl; ENSOANT00000009764; ENSOANP00000009762; ENSOANG00000006119.
DR   GeneID; 100081077; -.
DR   KEGG; oaa:100081077; -.
DR   CTD; 3760; -.
DR   eggNOG; KOG3827; Eukaryota.
DR   eggNOG; ENOG410XQ62; LUCA.
DR   GeneTree; ENSGT00970000193368; -.
DR   InParanoid; F6WTY3; -.
DR   KO; K04997; -.
DR   OMA; TTSEMTY; -.
DR   OrthoDB; 956263at2759; -.
DR   TreeFam; TF313676; -.
DR   Proteomes; UP000002279; Unplaced.
DR   Bgee; ENSOANG00000006119; Expressed in 5 organ(s), highest expression level in cerebellum.
DR   GO; GO:0099056; C:integral component of presynaptic membrane; IEA:Ensembl.
DR   GO; GO:0098688; C:parallel fiber to Purkinje cell synapse; IEA:Ensembl.
DR   GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:Ensembl.
DR   GO; GO:0015467; F:G-protein activated inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IBA:GO_Central.
DR   GO; GO:1990573; P:potassium ion import across plasma membrane; IBA:GO_Central.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR003274; K_chnl_inward-rec_Kir3.1.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PRINTS; PR01327; KIR31CHANNEL.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002279};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002279};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM     79    100       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    154    177       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       42    182       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      189    358       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   REGION        1     41       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
SQ   SEQUENCE   496 AA;  55649 MW;  8738AF81920C6719 CRC64;
     MSALRRKFGD DYRVVTTSSS GSGPRPAGPR PGPPRGKRQR FVDKNGRCNV QHGNLGGETS
     RYLSDLFTTL VDLKWRWNLS IFILTYTVAW LFMASMWWAI AYTRGDLSRA HAGNYTPCVA
     NVYNFPSAFL FFIETEATIG YGYRYITDKC PEGIVLFLFQ SILGSIVDAF LIGCMFIKMS
     QPKKRAETLM FSEHAVVSVR DGRLTLMFRV GNLRNSHMVS AQIRCKLLKS RQTPEGEFLP
     LDQLELDVGF STGADQLFLV SPLTICHVID AKSPFYDLSQ RSMQTEQFEI VVILEGIVET
     TGMTCQARTS YTEDEVLWGH RFFPVISLEE GFFKVDYSQF HATFEVPTPP YSVKEQEEMF
     LLSSPLIAPA ISNSKERNHS VECLDGLDDV GAKLPSKLQK MTGREDFPKK LLRMSSTTSE
     KAYSLGDLPM KLQRISSVPG NSEEKLGSKT TKILSDPISQ SVADLPPKLQ KMSGGAARME
     GNLPAKLRKM NSDRFT
//
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