ID F6WZ94_CALJA Unreviewed; 697 AA.
AC F6WZ94;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 2.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Sialic acid binding Ig like lectin 10 {ECO:0000313|Ensembl:ENSCJAP00000034377.2};
GN Name=SIGLEC10 {ECO:0000313|Ensembl:ENSCJAP00000034377.2};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000034377.2, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000034377.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000034377.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. SIGLEC (sialic
CC acid binding Ig-like lectin) family. {ECO:0000256|ARBA:ARBA00038361}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; F6WZ94; -.
DR STRING; 9483.ENSCJAP00000034377; -.
DR Ensembl; ENSCJAT00000036309.4; ENSCJAP00000034377.2; ENSCJAG00000018511.6.
DR GeneTree; ENSGT01080000257333; -.
DR HOGENOM; CLU_024444_5_1_1; -.
DR InParanoid; F6WZ94; -.
DR OMA; CWWLGEE; -.
DR Proteomes; UP000008225; Chromosome 22.
DR Bgee; ENSCJAG00000018511; Expressed in kidney and 1 other cell type or tissue.
DR GO; GO:0042612; C:MHC class I protein complex; IEA:UniProtKB-KW.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; IEA:UniProtKB-KW.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR CDD; cd05712; IgV_CD33; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003006; Ig/MHC_CS.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR12035; SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN; 1.
DR PANTHER; PTHR12035:SF96; SIALIC ACID-BINDING IG-LIKE LECTIN 16; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50835; IG_LIKE; 3.
DR PROSITE; PS00290; IG_MHC; 1.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Immunity {ECO:0000256|ARBA:ARBA00022451};
KW Lectin {ECO:0000256|ARBA:ARBA00022734};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW MHC I {ECO:0000256|ARBA:ARBA00022451};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..697
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015354817"
FT TRANSMEM 547..569
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 145..230
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 250..338
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 343..440
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 604..697
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 697 AA; 76828 MW; 8888483D5CF6758B CRC64;
MLLPLLLSSL LGGSQAMDGS FSIQVQMLVT VPQGLCVSVP CNLSYPRRDW TESTPAYGYW
FRERAETSED APVATNHPDR EVDMSTRGRF QLTGDPGKGS CSLVIRDAQM QDTGGYFFRV
ERGSYVKFNF LNSFHLKVTA LTQKPDVYIP ETLEPGRPVT VICVFNWAFE NCPLPSISWM
GAALSSRRTR PSSPHFSVLS FMPRPQDHDT NLTCQVDFSR TGVSAQRTVR LHVAYAPRDV
VISISRDNVP ALEPQPQGNV PYLEAQKGQF LRLLCAADSQ PPATLSWVLQ DRVLSWSHPW
GPRTLGLELP QVKAGDSGRY ICRAENRLGS QQRALDLSVQ YPPENLRVMV SQANRTVLEN
LGNGTSLPVL EGQSLRLACV THSSPPARLS WTRGGQTLSP SPPSDPAVLE LPRVQMEHEG
EFTCHAQHPL GSQHVSLSLS VHYPPQLLGP SCSWEAESLH CSCSSQASPA PSLCWWLGEE
LLEGNSSQDS FEVTLSSTGP WANSSLSLRG GLSSGLRLSC EAWNVHGAQS GSILQLPDQK
GLVSKEFFIG VVLGIMIMAL LFLCLSQIIM KILLKKQTQA ETPRPRFSRH STILDYINVV
PKAGPRAQNR NEKATSSSPS RTPPPPGAPC PESKKNQKKP YQLFSCPEPK SSTQAPESQE
SREELHYATL NFPGLRPRPE ARMPKGTQAD YAEVKFH
//
