ID F6X512_XENTR Unreviewed; 471 AA.
AC F6X512;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 4.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Upstream binding protein 1 {ECO:0000313|Ensembl:ENSXETP00000040787, ECO:0000313|RefSeq:XP_012827179.2};
GN Name=ubp1 {ECO:0000313|Ensembl:ENSXETP00000040787,
GN ECO:0000313|RefSeq:XP_012827179.2,
GN ECO:0000313|Xenbase:XB-GENE-958759};
GN Synonyms=cp-2 {ECO:0000313|RefSeq:XP_012827179.2}, cp2
GN {ECO:0000313|RefSeq:XP_012827179.2}, lbp-1
GN {ECO:0000313|RefSeq:XP_012827179.2}, lbp-1a
GN {ECO:0000313|RefSeq:XP_012827179.2}, lbp-1b
GN {ECO:0000313|RefSeq:XP_012827179.2}, lbp1
GN {ECO:0000313|RefSeq:XP_012827179.2}, lbp1a
GN {ECO:0000313|RefSeq:XP_012827179.2}, lbp1b
GN {ECO:0000313|RefSeq:XP_012827179.2}, tfcp2l1
GN {ECO:0000313|RefSeq:XP_012827179.2}, ubp-1
GN {ECO:0000313|RefSeq:XP_012827179.2};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|Ensembl:ENSXETP00000040787};
RN [1] {ECO:0000313|Ensembl:ENSXETP00000040787}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000040787};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [2] {ECO:0000313|Ensembl:ENSXETP00000040787}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUN-2011) to UniProtKB.
RN [3] {ECO:0000313|RefSeq:XP_012827179.2}
RP IDENTIFICATION.
RC STRAIN=Nigerian {ECO:0000313|RefSeq:XP_012827179.2};
RC TISSUE=Liver and blood {ECO:0000313|RefSeq:XP_012827179.2};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU01313}.
CC -!- SIMILARITY: Belongs to the grh/CP2 family. CP2 subfamily.
CC {ECO:0000256|ARBA:ARBA00010852}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_012827179.2; XM_012971725.3.
DR Ensembl; ENSXETT00000040787; ENSXETP00000040787; ENSXETG00000023707.
DR AGR; Xenbase:XB-GENE-958759; -.
DR Xenbase; XB-GENE-958759; ubp1.
DR HOGENOM; CLU_015127_2_0_1; -.
DR OMA; FKHEDSA; -.
DR Proteomes; UP000008143; Chromosome 10.
DR Bgee; ENSXETG00000023707; Expressed in neurula embryo and 4 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR007604; CP2.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR041418; SAM_3.
DR InterPro; IPR040167; TF_CP2-like.
DR PANTHER; PTHR11037:SF12; GRH_CP2 DB DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11037; TRANSCRIPTION FACTOR CP2; 1.
DR Pfam; PF04516; CP2; 1.
DR Pfam; PF18016; SAM_3; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS51968; GRH_CP2_DB; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU01313};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU01313};
KW Reference proteome {ECO:0000313|Proteomes:UP000008143}.
FT DOMAIN 46..284
FT /note="Grh/CP2 DB"
FT /evidence="ECO:0000259|PROSITE:PS51968"
FT REGION 226..245
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 265..314
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 293..314
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 471 AA; 53456 MW; D363B9BD8865FB84 CRC64;
MLFWHSQPEH YWPTPAEHYQ NPPSSIYRET IQLPFLKQED QTPIVPLCPA FQCVLCAPSS
PGIKLHEETL TYLNQGQSYE IRLLSNWKGL GELAEGRRLL RSVVRVVFHD RRLQYSERQQ
LESWQLNHPG DRILDIDIPL SVGVTDPLVN PNTLNTIEFL WDPSKRTSVF IQVNCISTEF
TQRKNGGEKG APFRIQVDTY KGDAHGGFTE HLYSCSCQVK VFKPKGADRK QKTDREKVEK
RSALEREKYQ PACESTILTE CIPWPDIEAP RSPPSTPSSF RMPTPERACA SPVCASDSST
ESSAEQSLSP SSSISETQQW LVRNRFSNYC RTFSNFTGAD LLKLSRKDLT QICGVADGIR
LAHSLSARSV RPRLTLYIAT DTSEKKTTDD TSQTVYQELY LEEMTAAELT TKVADLFSVP
ANHIQQISRT GPHGIHILLS DMMVRHMPDE SCFMATLQKM HNSDCFHCIL R
//
