ID F6XL06_MACMU Unreviewed; 752 AA.
AC F6XL06;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 3.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Double zinc ribbon and ankyrin repeat domains 1 {ECO:0000313|Ensembl:ENSMMUP00000005534.4};
GN Name=DZANK1 {ECO:0000313|Ensembl:ENSMMUP00000005534.4,
GN ECO:0000313|VGNC:VGNC:71842};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|Ensembl:ENSMMUP00000005534.4, ECO:0000313|Proteomes:UP000006718};
RN [1] {ECO:0000313|Proteomes:UP000006718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=17573 {ECO:0000313|Proteomes:UP000006718};
RX PubMed=17431167; DOI=10.1126/science.1139247;
RA Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M.,
RA Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C., Wilson R.K.,
RA Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W., Hardison R.C.,
RA Makova K.D., Miller W., Milosavljevic A., Palermo R.E., Siepel A.,
RA Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J.,
RA Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y., Dinh H.H.,
RA Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T., Godfrey J.,
RA Hawes A.C., Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N.,
RA Joshi V., Khan Z.M., Kirkness E.F., Cree A., Fowler R.G., Lee S.,
RA Lewis L.R., Li Z., Liu Y.-S., Moore S.M., Muzny D., Nazareth L.V.,
RA Ngo D.N., Okwuonu G.O., Pai G., Parker D., Paul H.A., Pfannkoch C.,
RA Pohl C.S., Rogers Y.-H.C., Ruiz S.J., Sabo A., Santibanez J.,
RA Schneider B.W., Smith S.M., Sodergren E., Svatek A.F., Utterback T.R.,
RA Vattathil S., Warren W., White C.S., Chinwalla A.T., Feng Y., Halpern A.L.,
RA Hillier L.W., Huang X., Minx P., Nelson J.O., Pepin K.H., Qin X.,
RA Sutton G.G., Venter E., Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P.,
RA Jones S.M., Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L.,
RA Csuros M., Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H.,
RA Liu Y., Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E.,
RA Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J.,
RA Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J.,
RA Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A.,
RA Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J., Denby A.,
RA Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A., Marklein A.,
RA Nielsen R., Vallender E.J., Clark A.G., Ferguson B., Hernandez R.D.,
RA Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S., Pu L.-L., Ren Y.,
RA Smith D.G., Wheeler D.A., Schenck I., Ball E.V., Chen R., Cooper D.N.,
RA Giardine B., Hsu F., Kent W.J., Lesk A., Nelson D.L., O'brien W.E.,
RA Pruefer K., Stenson P.D., Wallace J.C., Ke H., Liu X.-M., Wang P.,
RA Xiang A.P., Yang F., Barber G.P., Haussler D., Karolchik D., Kern A.D.,
RA Kuhn R.M., Smith K.E., Zwieg A.S.;
RT "Evolutionary and biomedical insights from the rhesus macaque genome.";
RL Science 316:222-234(2007).
RN [2] {ECO:0000313|Ensembl:ENSMMUP00000005534.4}
RP IDENTIFICATION.
RC STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000005534.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F6XL06; -.
DR SMR; F6XL06; -.
DR Ensembl; ENSMMUT00000005877.4; ENSMMUP00000005534.4; ENSMMUG00000004139.4.
DR VEuPathDB; HostDB:ENSMMUG00000004139; -.
DR VGNC; VGNC:71842; DZANK1.
DR GeneTree; ENSGT00390000000549; -.
DR Proteomes; UP000006718; Chromosome 10.
DR Bgee; ENSMMUG00000004139; Expressed in prefrontal cortex and 20 other cell types or tissues.
DR ExpressionAtlas; F6XL06; baseline.
DR GO; GO:0042995; C:cell projection; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR025874; DZR.
DR InterPro; IPR026876; Fn3_assoc_repeat.
DR PANTHER; PTHR16058; DOUBLE ZINC RIBBON AND ANKYRIN REPEAT-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR16058:SF4; DOUBLE ZINC RIBBON AND ANKYRIN REPEAT-CONTAINING PROTEIN 1; 1.
DR Pfam; PF12773; DZR; 1.
DR Pfam; PF13287; Fn3_assoc; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
PE 4: Predicted;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000006718};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 358..406
FT /note="DZANK-type"
FT /evidence="ECO:0000259|Pfam:PF12773"
FT REGION 161..202
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 161..176
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 752 AA; 82419 MW; B2B714198250921A CRC64;
MTAGSVCVPQ IIPLRVPQPG KANHEIDNNT LLEMKSDTPD VNIYYTLDGS KPEFLKRTGY
VENNTFKYTK PITLPDGKIQ VKAIAVSKDC RQSGIVTKVF QVGYESPNVV SPEDNVENVL
KDSSRQEFKN GLVGSKLKKK YQNSENQRSW NVNLRKFPDL QVGERTDPKT LKDLRFSESP
LEIPAHSGGS GSRPPTRQSQ SPGFAHISGL KCLTSTEIMR IQRETDFLKC AHCLAPRPSD
PFARFCQECG SPVPPIFGCR LPPPEGAQMG LCAECRSLVP MNTPICVVCE APLALQLQPQ
ASLHLKEKVI CRACGTGNPA HLRYCVTCEG ALPSSQESIC SGDKASPPPT QKGGTISCSR
CGRWNLWEAS FCGWCGAMLG IPAGCSVCPK CGASNHLSAR FCGSCGICVK SLVKLSLDRS
LALAAQEPRP FSEPQCAWQS LNIPLPRSDA GTKRDIGTQT VGLFYPSGKL LAKKELEIAS
QKQRQEKMSD HKPLLTAISP GRGYWRRQLD HISAHLRCYA QNNPEFRALI AEPRMGKLIS
ATVHEDGCEV SIRLNYSQVS NKNLYLNKAV NFSDHLLSSA AEGDGGLCGS RSSWVSDYSQ
STSDTIEKIK RIRNFKTKTF QEKEEQLLPE NRLLLKEVGP TGEGRVSVIE QLLDEGADPN
CCDEDNRPVI TVAVMNKHHE AIPVLVQRGA DIDQQWGPCN ASVRKKNAGG QTAYDLALNT
GDDLITSLFA AKFGQGLEDQ LAQTRSLRLD DC
//
