ID F6XW19_ORNAN Unreviewed; 649 AA.
AC F6XW19;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 2.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Zinc finger protein 143 {ECO:0000313|Ensembl:ENSOANP00000009318.3};
GN Name=ZNF143 {ECO:0000313|Ensembl:ENSOANP00000009318.3};
OS Ornithorhynchus anatinus (Duckbill platypus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Monotremata; Ornithorhynchidae; Ornithorhynchus.
OX NCBI_TaxID=9258 {ECO:0000313|Ensembl:ENSOANP00000009318.3, ECO:0000313|Proteomes:UP000002279};
RN [1] {ECO:0000313|Ensembl:ENSOANP00000009318.3, ECO:0000313|Proteomes:UP000002279}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000009318.3,
RC ECO:0000313|Proteomes:UP000002279};
RX PubMed=18464734; DOI=10.1038/nature06936;
RA Warren W.C., Hillier L.W., Marshall Graves J.A., Birney E., Ponting C.P.,
RA Grutzner F., Belov K., Miller W., Clarke L., Chinwalla A.T., Yang S.P.,
RA Heger A., Locke D.P., Miethke P., Waters P.D., Veyrunes F., Fulton L.,
RA Fulton B., Graves T., Wallis J., Puente X.S., Lopez-Otin C., Ordonez G.R.,
RA Eichler E.E., Chen L., Cheng Z., Deakin J.E., Alsop A., Thompson K.,
RA Kirby P., Papenfuss A.T., Wakefield M.J., Olender T., Lancet D.,
RA Huttley G.A., Smit A.F., Pask A., Temple-Smith P., Batzer M.A.,
RA Walker J.A., Konkel M.K., Harris R.S., Whittington C.M., Wong E.S.,
RA Gemmell N.J., Buschiazzo E., Vargas Jentzsch I.M., Merkel A., Schmitz J.,
RA Zemann A., Churakov G., Kriegs J.O., Brosius J., Murchison E.P.,
RA Sachidanandam R., Smith C., Hannon G.J., Tsend-Ayush E., McMillan D.,
RA Attenborough R., Rens W., Ferguson-Smith M., Lefevre C.M., Sharp J.A.,
RA Nicholas K.R., Ray D.A., Kube M., Reinhardt R., Pringle T.H., Taylor J.,
RA Jones R.C., Nixon B., Dacheux J.L., Niwa H., Sekita Y., Huang X., Stark A.,
RA Kheradpour P., Kellis M., Flicek P., Chen Y., Webber C., Hardison R.,
RA Nelson J., Hallsworth-Pepin K., Delehaunty K., Markovic C., Minx P.,
RA Feng Y., Kremitzki C., Mitreva M., Glasscock J., Wylie T., Wohldmann P.,
RA Thiru P., Nhan M.N., Pohl C.S., Smith S.M., Hou S., Nefedov M.,
RA de Jong P.J., Renfree M.B., Mardis E.R., Wilson R.K.;
RT "Genome analysis of the platypus reveals unique signatures of evolution.";
RL Nature 453:175-183(2008).
RN [2] {ECO:0000313|Ensembl:ENSOANP00000009318.3}
RP IDENTIFICATION.
RC STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000009318.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F6XW19; -.
DR STRING; 9258.ENSOANP00000009318; -.
DR Ensembl; ENSOANT00000009320.4; ENSOANP00000009318.3; ENSOANG00000005853.4.
DR eggNOG; KOG1721; Eukaryota.
DR GeneTree; ENSGT00940000157584; -.
DR HOGENOM; CLU_027168_0_0_1; -.
DR InParanoid; F6XW19; -.
DR OMA; YPSCGKK; -.
DR TreeFam; TF333498; -.
DR Proteomes; UP000002279; Chromosome 3.
DR Bgee; ENSOANG00000005853; Expressed in fibroblast and 7 other cell types or tissues.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IBA:GO_Central.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 7.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR19818:SF157; ZINC FINGER PROTEIN 76; 1.
DR PANTHER; PTHR19818; ZINC FINGER PROTEIN ZIC AND GLI; 1.
DR Pfam; PF00096; zf-C2H2; 4.
DR SMART; SM00355; ZnF_C2H2; 7.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 3.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 7.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 7.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Reference proteome {ECO:0000313|Proteomes:UP000002279};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 261..290
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 291..320
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 321..350
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 351..380
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 381..410
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 411..440
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 441..469
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
SQ SEQUENCE 649 AA; 70546 MW; 47967B394EC6CFEB CRC64;
MMLLAQINRD SQGMTEFPGG GMEAQHVTLC LTEAVAVADG DNLENMEGVS LQAVTLADGS
TAYIQHNSKD GKLMDGQVIQ LEDGSAAYVQ HVPMPKSRDS LRLEDGQAVQ LEDGTTAFIH
HTSKDSYDQS ALQAVQLEDG TTAYIHHSVQ VPQSDTILAI QADGTVAGLH TGDGTIDPDT
ISALEQYAAK ICSRRKKLCM DHSKKCKGRR NLERKVSIDG SESVGTGMMG ENEQEKKMQI
VLQGHGTRVP AKSQQSGEKA FRCDYDGCGK LYTTAHHLKV HERSHTGDRP YQCEHPGCGK
AFATGYGLKS HVRTHTGEKP YRCSEDNCTK SFKTSGDLQK HIRTHTGERP FKCPYEGCGR
SFTTSNIRKV HIRTHTGERP YYCTEPGCGR AFASATNYKN HVRIHTGEKP YVCTVPGCDK
RFTEYSSLYK HHVVHTHSKP YNCNHCGKTY KQISTLAMHK KTAHNDTEPI EEEQEAFFEP
PPGQGEDVLK GPQIAYVTGV EGEDVVSAQV AAVAQSGLGQ QVALISQDGT QHVNISQADM
QALGNTITMV TQDGTTITVP AHDAVISSAG THSVAMVTAE GTEGQQVAIV AQDLAAFHTA
SSEMGHQPHG HHLVTTETRP VTLLATSNGT QIAVQVSVIY SKFLRHAMI
//
