ID F6Y2B1_MACMU Unreviewed; 740 AA.
AC F6Y2B1;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 3.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Solute carrier family 4 member 1 adaptor protein {ECO:0000313|Ensembl:ENSMMUP00000036651.3};
GN Name=SLC4A1AP {ECO:0000313|Ensembl:ENSMMUP00000036651.3,
GN ECO:0000313|VGNC:VGNC:77696};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|Ensembl:ENSMMUP00000036651.3, ECO:0000313|Proteomes:UP000006718};
RN [1] {ECO:0000313|Proteomes:UP000006718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=17573 {ECO:0000313|Proteomes:UP000006718};
RX PubMed=17431167; DOI=10.1126/science.1139247;
RA Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M.,
RA Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C., Wilson R.K.,
RA Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W., Hardison R.C.,
RA Makova K.D., Miller W., Milosavljevic A., Palermo R.E., Siepel A.,
RA Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J.,
RA Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y., Dinh H.H.,
RA Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T., Godfrey J.,
RA Hawes A.C., Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N.,
RA Joshi V., Khan Z.M., Kirkness E.F., Cree A., Fowler R.G., Lee S.,
RA Lewis L.R., Li Z., Liu Y.-S., Moore S.M., Muzny D., Nazareth L.V.,
RA Ngo D.N., Okwuonu G.O., Pai G., Parker D., Paul H.A., Pfannkoch C.,
RA Pohl C.S., Rogers Y.-H.C., Ruiz S.J., Sabo A., Santibanez J.,
RA Schneider B.W., Smith S.M., Sodergren E., Svatek A.F., Utterback T.R.,
RA Vattathil S., Warren W., White C.S., Chinwalla A.T., Feng Y., Halpern A.L.,
RA Hillier L.W., Huang X., Minx P., Nelson J.O., Pepin K.H., Qin X.,
RA Sutton G.G., Venter E., Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P.,
RA Jones S.M., Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L.,
RA Csuros M., Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H.,
RA Liu Y., Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E.,
RA Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J.,
RA Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J.,
RA Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A.,
RA Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J., Denby A.,
RA Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A., Marklein A.,
RA Nielsen R., Vallender E.J., Clark A.G., Ferguson B., Hernandez R.D.,
RA Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S., Pu L.-L., Ren Y.,
RA Smith D.G., Wheeler D.A., Schenck I., Ball E.V., Chen R., Cooper D.N.,
RA Giardine B., Hsu F., Kent W.J., Lesk A., Nelson D.L., O'brien W.E.,
RA Pruefer K., Stenson P.D., Wallace J.C., Ke H., Liu X.-M., Wang P.,
RA Xiang A.P., Yang F., Barber G.P., Haussler D., Karolchik D., Kern A.D.,
RA Kuhn R.M., Smith K.E., Zwieg A.S.;
RT "Evolutionary and biomedical insights from the rhesus macaque genome.";
RL Science 316:222-234(2007).
RN [2] {ECO:0000313|Ensembl:ENSMMUP00000036651.3}
RP IDENTIFICATION.
RC STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000036651.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F6Y2B1; -.
DR SMR; F6Y2B1; -.
DR STRING; 9544.ENSMMUP00000036651; -.
DR PaxDb; 9544-ENSMMUP00000025964; -.
DR Ensembl; ENSMMUT00000043658.3; ENSMMUP00000036651.3; ENSMMUG00000019748.4.
DR VEuPathDB; HostDB:ENSMMUG00000019748; -.
DR VGNC; VGNC:77696; SLC4A1AP.
DR GeneTree; ENSGT00940000155320; -.
DR HOGENOM; CLU_015909_2_2_1; -.
DR InParanoid; F6Y2B1; -.
DR OMA; QQAIWTF; -.
DR OrthoDB; 126345at2759; -.
DR Proteomes; UP000006718; Chromosome 13.
DR Bgee; ENSMMUG00000019748; Expressed in spermatocyte and 22 other cell types or tissues.
DR ExpressionAtlas; F6Y2B1; baseline.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR CDD; cd19856; DSRM_Kanadaptin; 1.
DR CDD; cd22677; FHA_Kanadaptin; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 3.30.160.20; -; 1.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR23308:SF53; KANADAPTIN-RELATED; 1.
DR PANTHER; PTHR23308; NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1; 1.
DR Pfam; PF00035; dsrm; 1.
DR Pfam; PF00498; FHA; 1.
DR SMART; SM00240; FHA; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000006718}.
FT DOMAIN 135..195
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT REGION 1..107
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 254..282
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 563..740
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 445..472
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 34..54
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 591..605
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 606..623
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 631..667
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 683..697
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 740 AA; 82716 MW; 73952FBAF3DF04C5 CRC64;
MADFLSQSEP LASQELSGDF KKPALLVPAA ARSKAPATSS SNPEEVQKEG PTALQDPSSG
EPDVPPPQPD CGDFRSLQEE QSRPPTAVSS SGGPARAPPY QEPPWGGPAT APYSLEILKG
GAILGTRSLK GTSYCLFGRL SGCDVCLEHP SVSRYHAVLQ HRASGPDGEC DSNGPGFYLY
DLGSTHGTFL NKTRIPPRTY CRVHVGHVVR FGGSTRLFIL QGPEEDREAE SELTVTQLKE
LRKQQQILLE KKMLGEDSDE EEEMDTSERK INAGSQDDEM GCTWGMGEDA VEDDAEENPI
VLEFQQEREA FYIKDPKKAL QGFFDREGEE LEYEFDEQGH STWLCRVRLP VDDSTGKQLV
AEAIHSGKKK EAMIQCSLEA CRILDTLGLL RQEAVSRKRK AKNWEDEDFY DSDDDTFLDR
TGLVEKKRLN RMKKAGKIDE KPETFESLVA KLNDAERELS EISERLKASS QVLSESPSQD
SLDAFMSEMK SGSTLDGVSR KKLHLRTFEL RKEQQRLKGL IKIVKPAEIP ELKKTESQTT
GAENKAKKLT LPLFGAMKGG SKFKLKTGTV GKLPPKRPEL PPTLMRMKDE PEVEEEEEEE
EEEEKEKEEH EKKKLEDGSL SRPQPEIEPE AAVQEMRHPT DLTHFKETQT HENMSQLSEE
EQNKDYQDSS ETTSLCEGPS ASKNEYEKSR DELKKAPGPG KLPPTLSSKY PEDDPDYCVW
VPPEGQSGDG RTHLNDKYGY
//
