ID F6Y788_XENTR Unreviewed; 477 AA.
AC F6Y788;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 4.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Noelin-3 isoform X1 {ECO:0000313|RefSeq:XP_017949114.2};
DE SubName: Full=Olfactomedin 3 {ECO:0000313|Ensembl:ENSXETP00000029047};
GN Name=olfm3 {ECO:0000313|Ensembl:ENSXETP00000029047,
GN ECO:0000313|RefSeq:XP_017949114.2,
GN ECO:0000313|Xenbase:XB-GENE-960616};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|Ensembl:ENSXETP00000029047};
RN [1] {ECO:0000313|Ensembl:ENSXETP00000029047}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000029047};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [2] {ECO:0000313|Ensembl:ENSXETP00000029047}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUN-2011) to UniProtKB.
RN [3] {ECO:0000313|RefSeq:XP_017949114.2}
RP IDENTIFICATION.
RC STRAIN=Nigerian {ECO:0000313|RefSeq:XP_017949114.2};
RC TISSUE=Liver and blood {ECO:0000313|RefSeq:XP_017949114.2};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}. Synapse
CC {ECO:0000256|ARBA:ARBA00034103}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00446}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_017949114.2; XM_018093625.2.
DR Ensembl; ENSXETT00000029047; ENSXETP00000029047; ENSXETG00000013268.
DR KEGG; xtr:100492273; -.
DR AGR; Xenbase:XB-GENE-960616; -.
DR Xenbase; XB-GENE-960616; olfm3.
DR eggNOG; KOG3545; Eukaryota.
DR HOGENOM; CLU_035236_0_0_1; -.
DR OMA; XELKEKM; -.
DR TreeFam; TF315964; -.
DR Proteomes; UP000008143; Chromosome 4.
DR Bgee; ENSXETG00000013268; Expressed in brain and 4 other cell types or tissues.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
DR InterPro; IPR022082; Noelin_dom.
DR InterPro; IPR003112; Olfac-like_dom.
DR InterPro; IPR011044; Quino_amine_DH_bsu.
DR PANTHER; PTHR23192:SF36; NOELIN-3; 1.
DR PANTHER; PTHR23192; OLFACTOMEDIN-RELATED; 1.
DR Pfam; PF12308; Noelin-1; 1.
DR Pfam; PF02191; OLF; 1.
DR SMART; SM00284; OLF; 1.
DR SUPFAM; SSF50969; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR PROSITE; PS51132; OLF; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000008143};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Synapse {ECO:0000256|ARBA:ARBA00023018}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..477
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041197298"
FT DOMAIN 218..469
FT /note="Olfactomedin-like"
FT /evidence="ECO:0000259|PROSITE:PS51132"
FT COILED 79..134
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 477 AA; 54576 MW; 59407A3E08C142C4 CRC64;
MGSPFLTLGA VLCTMAMISN WMSQTLPSLV GLNTTGLSSG KALTQISPRE GWQVYSSAQD
SDGRCICTVV APEQNLCSRD AKSKQLRQLL EKVQNMSQSI EVLNLRTERD YQYVQKMETQ
MKVVRVKFRQ IEEDRKTLLT RHFQDLKEKM DDLLPLIPVL EQYKTDAQLI TQFKEEIRNL
TGILTNIQQE IGAFDYEELH QRVLGLETRL RDCMKKLTCG KLMKITGPVT VKASGPRFGA
WMTDPIASEK NNRVWYMDGF TSRIVREYRS IADFVTGTES RTYNLPYKWA GTSHLVYNGS
LFFNKFQSNI VIKYSFATGR ILNQRSLDNA GFNNVYPYTW GGHSDIDLMA DEFGVWAVYA
TNQNAGNIVI SQLRQDTLEV VKSWSTGYPK RSAGESFMIC GTLYVTNSHL TGAKVFYSYS
TKTSTYEYTD IPFHNQYFHI SMLDYNSRDR ALYAWNNGHQ VLFNVTLFHI IKTDNDA
//
