ID F6YNY8_MOUSE Unreviewed; 466 AA.
AC F6YNY8;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=UDP-glucose glycoprotein glucosyltransferase 2 {ECO:0000313|Ensembl:ENSMUSP00000117738.2};
DE Flags: Fragment;
GN Name=Uggt2 {ECO:0000313|Ensembl:ENSMUSP00000117738.2,
GN ECO:0000313|MGI:MGI:1913685};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000117738.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000117738.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000117738.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000117738.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000117738.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F6YNY8; -.
DR SMR; F6YNY8; -.
DR MaxQB; F6YNY8; -.
DR PeptideAtlas; F6YNY8; -.
DR ProteomicsDB; 303980; -.
DR Antibodypedia; 24874; 159 antibodies from 21 providers.
DR Ensembl; ENSMUST00000127153.2; ENSMUSP00000117738.2; ENSMUSG00000042104.19.
DR AGR; MGI:1913685; -.
DR MGI; MGI:1913685; Uggt2.
DR VEuPathDB; HostDB:ENSMUSG00000042104; -.
DR GeneTree; ENSGT00390000004600; -.
DR HOGENOM; CLU_587368_0_0_1; -.
DR ChiTaRS; Uggt2; mouse.
DR Proteomes; UP000000589; Chromosome 14.
DR Bgee; ENSMUSG00000042104; Expressed in spermatocyte and 148 other cell types or tissues.
DR ExpressionAtlas; F6YNY8; baseline and differential.
DR GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR GO; GO:0032991; C:protein-containing complex; ISO:MGI.
DR GO; GO:0003980; F:UDP-glucose:glycoprotein glucosyltransferase activity; IBA:GO_Central.
DR GO; GO:0051082; F:unfolded protein binding; IBA:GO_Central.
DR GO; GO:0071712; P:ER-associated misfolded protein catabolic process; IBA:GO_Central.
DR GO; GO:0018279; P:protein N-linked glycosylation via asparagine; IBA:GO_Central.
DR InterPro; IPR009448; UDP-g_GGtrans.
DR InterPro; IPR040692; UGGT_TRXL_3.
DR InterPro; IPR040525; UGGT_TRXL_4.
DR PANTHER; PTHR11226; UDP-GLUCOSE GLYCOPROTEIN:GLUCOSYLTRANSFERASE; 1.
DR PANTHER; PTHR11226:SF1; UDP-GLUCOSE:GLYCOPROTEIN GLUCOSYLTRANSFERASE 2; 1.
DR Pfam; PF18402; Thioredoxin_14; 1.
DR Pfam; PF18403; Thioredoxin_15; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|MaxQB:F6YNY8,
KW ECO:0007829|PeptideAtlas:F6YNY8};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT DOMAIN 1..200
FT /note="UGGT thioredoxin-like"
FT /evidence="ECO:0000259|Pfam:PF18402"
FT DOMAIN 225..446
FT /note="UDP-glucose:glycoprotein glucosyltransferase
FT thioredoxin-like"
FT /evidence="ECO:0000259|Pfam:PF18403"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000117738.2"
SQ SEQUENCE 466 AA; 52932 MW; E8EB3DA0D87C01C8 CRC64;
VLFIDPAQEY TLDFINLAEF FYFNEIPLRI GFVFILNVDN EVDGTTDAGV ALWRAFNYIE
EKYDVSEAFI SMTHMYQEVK GHRILTVDEV KSILQNKCPH ADILDILGIH SKYDGRRMEG
ATFYKMTGLG PLPQALYNGE PFDLKEMNTE ELKGAVLEKM VGTFVDLQRD VFMGTIRDET
SAIDFLMDKS NVVSRLNSLI LQTEPQYLNL LSSSVTADIE DFSTFSFLDS QDKSAVIAKH
MHYVTQEDAV ISPVTLWIIA DFDVPSGRKL LFNALKHMET SFHSRLGIVY NPTSKINEES
TVISRGILAA FLTHKNKHLR SFLRRLAEEE TAEAIYSGDK VQTFLAVEMD KNAFEKKYNT
VGVNIFRTHQ LFCQDVLKLR PGEPGIISNG KFLGPLSDEL YQEDFHLLEK ITFSNSLQNI
AGIVESMDMN SKHMSDLVMK IDGLMSSLAV RASRYDVTLL KENLRI
//
