ID F6YPZ1_MOUSE Unreviewed; 141 AA.
AC F6YPZ1;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Receptor (calcitonin) activity modifying protein 2 {ECO:0000313|Ensembl:ENSMUSP00000102903.4};
DE Flags: Fragment;
GN Name=Ramp2 {ECO:0000313|Ensembl:ENSMUSP00000102903.4,
GN ECO:0000313|MGI:MGI:1859650};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000102903.4, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000102903.4, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000102903.4,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000102903.4}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000102903.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RAMP family.
CC {ECO:0000256|ARBA:ARBA00007087}.
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DR AlphaFoldDB; F6YPZ1; -.
DR SMR; F6YPZ1; -.
DR MaxQB; F6YPZ1; -.
DR PeptideAtlas; F6YPZ1; -.
DR ProteomicsDB; 367265; -.
DR Antibodypedia; 29403; 312 antibodies from 32 providers.
DR Ensembl; ENSMUST00000107282.4; ENSMUSP00000102903.4; ENSMUSG00000001240.14.
DR AGR; MGI:1859650; -.
DR MGI; MGI:1859650; Ramp2.
DR VEuPathDB; HostDB:ENSMUSG00000001240; -.
DR GeneTree; ENSGT00940000160264; -.
DR HOGENOM; CLU_116349_2_0_1; -.
DR ChiTaRS; Ramp2; mouse.
DR Proteomes; UP000000589; Chromosome 11.
DR Bgee; ENSMUSG00000001240; Expressed in right lung and 244 other cell types or tissues.
DR ExpressionAtlas; F6YPZ1; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0015026; F:coreceptor activity; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0008277; P:regulation of G protein-coupled receptor signaling pathway; IEA:InterPro.
DR Gene3D; 1.10.150.510; Receptor activity modifying family; 1.
DR InterPro; IPR006985; RAMP.
DR InterPro; IPR038126; RAMP_sf.
DR PANTHER; PTHR14076; RECEPTOR ACTIVITY MODIFYING PROTEIN RAMP; 1.
DR PANTHER; PTHR14076:SF9; RECEPTOR ACTIVITY-MODIFYING PROTEIN 2; 1.
DR Pfam; PF04901; RAMP; 1.
PE 1: Evidence at protein level;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Proteomics identification {ECO:0007829|MaxQB:F6YPZ1,
KW ECO:0007829|ProteomicsDB:F6YPZ1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 111..132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000102903.4"
FT NON_TER 141
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000102903.4"
SQ SEQUENCE 141 AA; 16035 MW; 94354F694557D30F CRC64;
PESQNQSHPT EDSLVSKAYV PTGKMEDYET HVLPCWYEYK SCMDSVKDWC NWTLISRHYS
DLQNCLEYNA DKFGLGFPNP LAENIILEAH LIHFANCSLV QPTFSDPPED VLLAMIIAPI
CLIPFLVTLV VWRSKDSDAQ A
//
