ID F6YZN4_CALJA Unreviewed; 516 AA.
AC F6YZN4;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 3.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Zinc finger protein 215 {ECO:0000313|Ensembl:ENSCJAP00000025385.3};
GN Name=ZNF215 {ECO:0000313|Ensembl:ENSCJAP00000025385.3};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000025385.3, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000025385.3}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000025385.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00187}.
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DR RefSeq; XP_002755012.1; XM_002754966.2.
DR AlphaFoldDB; F6YZN4; -.
DR STRING; 9483.ENSCJAP00000025385; -.
DR Ensembl; ENSCJAT00000026825.4; ENSCJAP00000025385.3; ENSCJAG00000013794.5.
DR GeneID; 100414914; -.
DR KEGG; cjc:100414914; -.
DR CTD; 7762; -.
DR eggNOG; KOG1721; Eukaryota.
DR GeneTree; ENSGT00940000163217; -.
DR HOGENOM; CLU_002678_49_8_1; -.
DR InParanoid; F6YZN4; -.
DR OMA; VSWQQET; -.
DR TreeFam; TF350807; -.
DR Proteomes; UP000008225; Chromosome 11.
DR Bgee; ENSCJAG00000013794; Expressed in cerebellum and 1 other cell type or tissue.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR CDD; cd07936; SCAN; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 4.
DR Gene3D; 1.10.4020.10; DNA breaking-rejoining enzymes; 1.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR003309; SCAN_dom.
DR InterPro; IPR038269; SCAN_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR23232; KRAB DOMAIN C2H2 ZINC FINGER; 1.
DR PANTHER; PTHR23232:SF90; KRAB DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF02023; SCAN; 1.
DR Pfam; PF00096; zf-C2H2; 4.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00431; SCAN; 1.
DR SMART; SM00355; ZnF_C2H2; 4.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 3.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR SUPFAM; SSF47353; Retrovirus capsid dimerization domain-like; 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS50804; SCAN_BOX; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 4.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 4.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00187};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 48..126
FT /note="SCAN box"
FT /evidence="ECO:0000259|PROSITE:PS50804"
FT DOMAIN 164..237
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 378..405
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 406..433
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 461..488
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 489..516
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 138..158
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 138..156
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 516 AA; 59992 MW; 2441DB3D232820DB CRC64;
MQPLSKLMAI SKPQNLSLHE KRDFLRADLS WQQETTPVME TQDSEASRQK FRHFQYLKVS
GPHEALSQLW ELCVQWLRPE IHTKKQIIEL LVLEQFLAVL PEEVRTWVNL QHPNNSKDVV
TLMENVIEML KDEDTPCKDS VPQKASIKDK MKADSLTGKP QEPVTFKDVV VEFSKEEWGQ
LDSAVKNLYR DVMLENFRNL NSLRKAHLLS KPVESLELKN KKKRWITEKE ISRKTISDMQ
SISGEETSHG VIMTRLTKSG QPFSDVWKDE DWLYRNQKKQ DIDLPQEFPE TIYTEEEDFG
CSENKKSFDI NSVSSICAIQ QGIPKCEGSP KCDKWKTHFK FNLDSVGKQH SEYDEYGNDF
SLSTDIQHQE SHTTMNFYEC YQCGKAFCRS SSLIRHQIIH TGEKPYKCSE CGRFFNRRTN
LTKHQKLHTE AKACTSNKSQ KAFCKSEDSN NSTVHFRNNS YECVNCGKSF NRSSSLIRHQ
IIHTGEKPFK CKECNKAFNR SSNLVKHQKL HTQDKS
//
