ID F6ZC98_CALJA Unreviewed; 1894 AA.
AC F6ZC98;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 3.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=CDK5 regulatory subunit-associated protein 2 {ECO:0000256|ARBA:ARBA00020479};
GN Name=CDK5RAP2 {ECO:0000313|Ensembl:ENSCJAP00000037867.4};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000037867.4, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000037867.4}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000037867.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Golgi
CC apparatus {ECO:0000256|ARBA:ARBA00004555}.
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DR RefSeq; XP_002806563.1; XM_002806517.4.
DR Ensembl; ENSCJAT00000039995.5; ENSCJAP00000037867.4; ENSCJAG00000020351.5.
DR GeneID; 100386466; -.
DR KEGG; cjc:100386466; -.
DR CTD; 55755; -.
DR GeneTree; ENSGT00950000183190; -.
DR OrthoDB; 2912560at2759; -.
DR Proteomes; UP000008225; Chromosome 1.
DR Bgee; ENSCJAG00000020351; Expressed in testis and 6 other cell types or tissues.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0005815; C:microtubule organizing center; IEA:InterPro.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro.
DR InterPro; IPR042791; CDK5RAP2.
DR InterPro; IPR012943; Cnn_1N.
DR PANTHER; PTHR46930; CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 2; 1.
DR PANTHER; PTHR46930:SF1; CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF07989; Cnn_1N; 1.
PE 4: Predicted;
KW Calmodulin-binding {ECO:0000256|ARBA:ARBA00022860};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225}.
FT DOMAIN 60..132
FT /note="Centrosomin N-terminal motif 1"
FT /evidence="ECO:0000259|Pfam:PF07989"
FT REGION 268..287
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 896..916
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1014..1051
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1348..1374
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1468..1523
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1647..1667
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 60..177
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 394..485
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 591..621
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 961..988
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1205..1232
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1396..1430
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1029..1043
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1348..1368
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1470..1489
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1498..1523
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1894 AA; 215353 MW; E249010B315FFB68 CRC64;
MMDSVLEEDV TLPGTLSGCS GLVPNVPDDL DGITPKAGLG NSGLPNVSEE TVSPTRARNM
KDFENQITEL KKENFNLKLR IYFLEERMQQ EFHGPTEHIY KTNIELKVEV ESLKRELQER
ERLLIKASKA VESLAEAGGS EIQRVKEDAR KKVQQVEDLL TKRIRVLQKD VKAAQAELEK
AFAGTETEKA LRLSLESKLS EMKKMHEGDL EMALVLDEKD RLIEELKLSL KSKEALIQCL
EEEKSQMASP DENVSSGELR GLCAARREEK ERETEAAQME HQKERNSFEE RIQALEEDLR
EKEREISTEK KNSLKRDKAI QGLTMALKSK EKEVEGLNSE IEELSAAFAK AREALQKAQT
QEFQGSEGYE AALSGKEALL AELRSQNLTK STENHRLRRS IKKITQELSD LQQERERLEK
DLEEAHREKS KGDCTIRDLR NEVEKLRNEV NEREKAMEDR YKSLLSESNK KLHSQEQAIK
HLTESTNQKD LLLQKLSEKD LEVIQQNCYL MAAEDLQLRS EGLITGKCSS QQSPGSKTIF
SKEKKQSSDY EELIQVLKKE QDIYTHLVKS LQESDSINNL QAELNNIFVL RKQLEWDVLS
YQNLRKTLEE QIGEIRRREE ESFSFYSDQT SYLSICLEEN NRFQVEHFSQ EELKKKVSDL
IQLVKELYTD NQHLKKTIFD LSCMGFQGNG FPDRLESTEK TELLASKEDE DTIKTGEDDE
NNFLSDQHLQ QSNEVMKDLS KGGCKNGYLR HTESKILDYD GANTPGCLEE GEFMNMLAPL
FNEKATLLLE SRPDLLKVLQ ELLLGQLSLT EQEVSGEHLD GKTEKTPEQK GELRYFVQTN
SFSKPRDELK LSCEAQLVKA GGVPKVELTD ASVQTVATEG DLLRFKHEAK REAWNEQSTN
TVLSTEHRPE NLLRGPGWQA ALPSFPGGTN REAKKSRLPI LIKPSGSSGN MYHLPGTQEV
VAQLQNQILE LQGELKELKT CNEQLHQKLI LAEAMEDGRP TPDKTLLNAQ SSVGEAYQDS
PGEQKGIKTT SAWRDKEMDS DQQTSYEIDS DVCPPDDLAI LPSCKENPED VLSPTSIATC
LSSKSQPSVK VSVMGTDQSE SIDTSNETEY LKQKIHDLET ELEGYQNFIF HLQKHSQCSE
AIITVLCGTE GTQDGLNKPK GGSDEEEMTF SSLHQVRYVK HMKILHPLAP EMMDGRMPEN
LKQQLEEQEY ELQKEQNLNM ELLSEIHNMQ NKFRDLSPSR YDSLVQSQAR ELSLQRQQIK
DGHGICVISR QRMNTMIKAF EELLQASDVD CCVAEGFQEQ LNQCAELLEK LEKLFLSGKS
AGVEMNTHTQ NELMERIEED NLTSQHVLTE SPEPSASHAL SDYETSEKSF FSQDQKQDNE
MEKTSVMVNN FSQDLLMEHI QEIRTLRKRL EESIKTNEKL RKQLERQGSD FDQGSTNIFA
SGSELHSSLT SEIHFLRKQN EALNAMLIKG SRDKQKENDK LRESLSRKTA SLEHLQQEYA
SVKEENERLQ KEGSEKERHS QELIQEARHS RQELSRVQEE VKLRQQLLSQ NDKLLQSLRV
ELKAYEKLDE EHRRPRESSG EGWKGQDPFT DLHSLLMEIQ ALRLQLERSI QTNSTLQSRL
EEQLARGAEK AQEGALTLAA QALSIPELPL QPNKHDGDKY PMESDNSFDL FDSTQAVTPK
SVSETPPLSG NDTDSLPCNG GSLATSTPCV SCLVTGHRLW ADKSGCHVLG LIEDYEALLK
QIGQGQRLLA EMYIQIQETP SSESQELGTK GPHLVPLSKF VSSVSTARLT LEEAYRRLTH
LWRVSLPSDG QCPLHCKQIG EMKTEITKLH KKLFEQEKKL QNTVKLLQLS KRQEKVIFDQ
LVVTHKILRK ARGNLELRPR GAHPGTCSPS RPGS
//
