ID F6ZNX4_ORNAN Unreviewed; 394 AA.
AC F6ZNX4;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 2.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=OXA1L mitochondrial inner membrane protein {ECO:0000313|Ensembl:ENSOANP00000017010.2};
GN Name=OXA1L {ECO:0000313|Ensembl:ENSOANP00000017010.2};
OS Ornithorhynchus anatinus (Duckbill platypus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Monotremata; Ornithorhynchidae; Ornithorhynchus.
OX NCBI_TaxID=9258 {ECO:0000313|Ensembl:ENSOANP00000017010.2, ECO:0000313|Proteomes:UP000002279};
RN [1] {ECO:0000313|Ensembl:ENSOANP00000017010.2}
RP IDENTIFICATION.
RC STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000017010.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU003945}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU003945}.
CC Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004448}.
CC -!- SIMILARITY: Belongs to the OXA1/ALB3/YidC family.
CC {ECO:0000256|ARBA:ARBA00009877, ECO:0000256|RuleBase:RU003945}.
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DR AlphaFoldDB; F6ZNX4; -.
DR Ensembl; ENSOANT00000017013.2; ENSOANP00000017010.2; ENSOANG00000010724.3.
DR GeneTree; ENSGT00530000063506; -.
DR HOGENOM; CLU_029282_3_1_1; -.
DR Proteomes; UP000002279; Unplaced.
DR Bgee; ENSOANG00000010724; Expressed in heart and 7 other cell types or tissues.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0032977; F:membrane insertase activity; IEA:InterPro.
DR CDD; cd20069; 5TM_Oxa1-like; 1.
DR InterPro; IPR001708; YidC/ALB3/OXA1/COX18.
DR InterPro; IPR028055; YidC/Oxa/ALB_C.
DR NCBIfam; TIGR03592; yidC_oxa1_cterm; 1.
DR PANTHER; PTHR12428:SF66; MITOCHONDRIAL INNER MEMBRANE PROTEIN OXA1L; 1.
DR PANTHER; PTHR12428; OXA1; 1.
DR Pfam; PF02096; 60KD_IMP; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002279};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003945};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 103..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 227..246
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 267..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 105..298
FT /note="Membrane insertase YidC/Oxa/ALB C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02096"
FT REGION 363..394
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 394 AA; 43727 MW; 6D1E211DA90DA708 CRC64;
HKVSGHSRCR PELLLRPEGR LHRLSLTPRC LSTTPTVWAE TQVPPALPAA PPPTALTEVA
PDGAADIAQA AAEQSLTELG LASYTPVGMV QNLLEYIHID MGLPWWGAIV TCTVAARCLI
FPLIVKGQRE AVKINNHMPE IQKLSARMNE AKMSGDKFEF SRAYSDLQLY QKKHDVSPLR
GFIVPLAQAP IFISFFIALR EMAYLPVPSM QSGGLLWFPD LTVADPFYAL PLLVTASMWA
VLELGAETGV NNANLRVMKT VIRVMPLVVL PFTIHFPTAV FTYWLSSNLF SLAQVAFLRV
PAVRTRLGIP ARLVHDPAQL PPQEGLIKSI KTGWKNAQAA HKMQERERRM QNHLELAAKG
PLRQTFAHNP LLQPGKEKPP SKPRPKRPWQ DTIG
//
