ID   F7AK10_CALJA            Unreviewed;       888 AA.
AC   F7AK10;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   25-MAY-2022, sequence version 3.
DT   27-MAR-2024, entry version 65.
DE   SubName: Full=Transient receptor potential cation channel subfamily C member 7 {ECO:0000313|Ensembl:ENSCJAP00000001059.4};
GN   Name=TRPC7 {ECO:0000313|Ensembl:ENSCJAP00000001059.4};
OS   Callithrix jacchus (White-tufted-ear marmoset).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Callitrichinae; Callithrix; Callithrix.
OX   NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000001059.4, ECO:0000313|Proteomes:UP000008225};
RN   [1] {ECO:0000313|Ensembl:ENSCJAP00000001059.4}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCJAP00000001059.4}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; F7AK10; -.
DR   Ensembl; ENSCJAT00000001126.5; ENSCJAP00000001059.4; ENSCJAG00000005983.5.
DR   GeneTree; ENSGT01060000248588; -.
DR   Proteomes; UP000008225; Chromosome 2.
DR   Bgee; ENSCJAG00000005983; Expressed in cerebellum.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005262; F:calcium channel activity; IEA:InterPro.
DR   Gene3D; 1.10.287.70; -; 1.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR013555; TRP_dom.
DR   InterPro; IPR005463; TRPC7_channel.
DR   InterPro; IPR002153; TRPC_channel.
DR   NCBIfam; TIGR00870; trp; 1.
DR   PANTHER; PTHR10117:SF9; SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 7; 1.
DR   PANTHER; PTHR10117; TRANSIENT RECEPTOR POTENTIAL CHANNEL; 1.
DR   Pfam; PF12796; Ank_2; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF08344; TRP_2; 1.
DR   PRINTS; PR01097; TRNSRECEPTRP.
DR   PRINTS; PR01648; TRPCHANNEL7.
DR   SMART; SM00248; ANK; 3.
DR   SMART; SM01420; TRP_2; 1.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
PE   4: Predicted;
KW   ANK repeat {ECO:0000256|ARBA:ARBA00023043};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        411..430
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        496..518
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        605..627
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        676..695
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          279..341
FT                   /note="Transient receptor ion channel"
FT                   /evidence="ECO:0000259|SMART:SM01420"
SQ   SEQUENCE   888 AA;  102402 MW;  75153B6C6BBE5632 CRC64;
     MQSSFDGRDQ ASWVAVIYCQ HEEQRSALSP RCNSTHLASS VLQHHGERYI LGYHPWGASF
     PRLSTGFRSS RGGTSLRILP SMLGSSTFKN MQRRHTTLRE KGRRQAIRGP AYMFNEKGTS
     LTPEEERFLD SAEYGNIPVV RKMLEESKTL NFNCVDYMGQ NALQLAVGNE HLEVTELLLK
     KENLARVGDA LLLAISKGYV RIVEAILNHP AFAQGQRLTL SPLEQELRDD DFYAYDEDGT
     RFSHDITPII LAAHCQEYEI VHILLLKGAR IERPHDYFCK CNECTEKQRK DSFSHSRSRM
     NAYKGLASAA YLSLSSEDPV LTALELSNEL ARLANIETEF KNDYRKLSMQ CKDFVVGVLD
     LCRDTEEVEA ILNGDVNFQV WSDHHRPSLS RIKLAIKYEV KKLGRTLRSP FMKFVAHAVS
     FTIFLGLLVV NASDRFEGVK TLPNETFTDY PKQIFRVKTT QFSWTEMLIM KWVLGMIWSE
     CKEIWEEGPR EYVLHLWNLL DFGMLSIFVA SFTARFMAFL KASEAQLYVD QHVRDDTLHN
     VSLPPEVAYF TYARDKWWPS DPQIISEGLY AIAVVLSFSR IAYILPANES FGPLQISLGR
     TVKDIFKFMV IFIMVFVAFM IGMFNLYSYY RGAKYNPAFT TVEESFKTLF WSIFGLSEVI
     SVVLKYDHKF IENIGYVLYG VYNVTMVVVL LNMLIAMINN SYQEIEEDAD VEWKFARAKL
     WLSYFDEGRT LPAPFNLVPS PKSFYYLIMR IKMCLIKLCK SKAKNCENDL EMGMLNSKFK
     KTRYQAGMRN SENLTANNTF SKPTRYQKIM KRLIKRYVLK AQVDRENDEV NEGELKEIKQ
     DISSLRYELL EEKSQATGEL ADLIQQLSEK FGKNLNKDHL RVNKGKDI
//