ID F7AKI7_XENTR Unreviewed; 386 AA.
AC F7AKI7; Q6NVU0;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 3.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Radial spoke 3 homolog {ECO:0000313|EMBL:AAH67913.1};
DE SubName: Full=Radial spoke head 3 {ECO:0000313|Ensembl:ENSXETP00000021540};
DE SubName: Full=Radial spoke head protein 3 homolog {ECO:0000313|RefSeq:NP_998863.1, ECO:0000313|RefSeq:XP_031757473.1};
GN Name=rsph3 {ECO:0000313|EMBL:AAH67913.1,
GN ECO:0000313|Ensembl:ENSXETP00000021540,
GN ECO:0000313|RefSeq:NP_998863.1, ECO:0000313|RefSeq:XP_031757473.1,
GN ECO:0000313|Xenbase:XB-GENE-989659};
GN Synonyms=rshl2 {ECO:0000313|RefSeq:NP_998863.1,
GN ECO:0000313|RefSeq:XP_031757473.1}, rsp3
GN {ECO:0000313|RefSeq:NP_998863.1, ECO:0000313|RefSeq:XP_031757473.1};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|Ensembl:ENSXETP00000021540};
RN [1] {ECO:0000313|RefSeq:NP_998863.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12454917; DOI=10.1002/dvdy.10174;
RA Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA Richardson P.;
RT "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT initiative.";
RL Dev. Dyn. 225:384-391(2002).
RN [2] {ECO:0000313|EMBL:AAH67913.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo {ECO:0000313|EMBL:AAH67913.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSXETP00000021540}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000021540};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [4] {ECO:0000313|Ensembl:ENSXETP00000021540}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUN-2011) to UniProtKB.
RN [5] {ECO:0000313|RefSeq:NP_998863.1, ECO:0000313|RefSeq:XP_031757473.1}
RP IDENTIFICATION.
RC STRAIN=Nigerian {ECO:0000313|RefSeq:XP_031757473.1};
RC TISSUE=Liver and blood {ECO:0000313|RefSeq:XP_031757473.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, flagellum axoneme
CC {ECO:0000256|ARBA:ARBA00004611}.
CC -!- SIMILARITY: Belongs to the flagellar radial spoke RSP3 family.
CC {ECO:0000256|ARBA:ARBA00006737}.
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DR EMBL; BC067913; AAH67913.1; -; mRNA.
DR RefSeq; NP_998863.1; NM_213698.1.
DR RefSeq; XP_012818314.1; XM_012962860.2.
DR RefSeq; XP_031757473.1; XM_031901613.1.
DR STRING; 8364.ENSXETP00000031273; -.
DR PaxDb; 8364-ENSXETP00000021540; -.
DR DNASU; 407929; -.
DR Ensembl; ENSXETT00000021540; ENSXETP00000021540; ENSXETG00000009778.
DR GeneID; 407929; -.
DR KEGG; xtr:407929; -.
DR AGR; Xenbase:XB-GENE-989659; -.
DR CTD; 83861; -.
DR Xenbase; XB-GENE-989659; rsph3.
DR eggNOG; ENOG502QQSZ; Eukaryota.
DR HOGENOM; CLU_036980_0_0_1; -.
DR OMA; QDEGWFA; -.
DR OrthoDB; 5481996at2759; -.
DR TreeFam; TF324184; -.
DR Proteomes; UP000008143; Chromosome 5.
DR Bgee; ENSXETG00000009778; Expressed in testis and 12 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR GO; GO:0031514; C:motile cilium; IEA:UniProtKB-KW.
DR InterPro; IPR009290; Radial_spoke_3.
DR PANTHER; PTHR21648; FLAGELLAR RADIAL SPOKE PROTEIN 3; 1.
DR PANTHER; PTHR21648:SF0; RADIAL SPOKE HEAD PROTEIN 3 HOMOLOG; 1.
DR Pfam; PF06098; Radial_spoke_3; 1.
PE 2: Evidence at transcript level;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Flagellum {ECO:0000256|ARBA:ARBA00022846};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000008143}.
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 220..239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 345..386
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 345..360
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 365..386
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 386 AA; 45152 MW; CF887F0E7614CA31 CRC64;
MTSVIPRQKE MGSGTYTFSS QPRVVQNRRK YRGVQPTVNE ESFTYGNIMY DRRVVRGNTY
AQHTLPLSAQ PDPIEFQRQQ EAQRRALAKK RAKELLRPRT PEAVEGRKHI DVQTELYLEE
LSDRVEEKDM ECQTDAFLDR PPTPLFIPAK TGADVATQIL EGELFDFDLE VKPMLEVLVG
KTIEQALLEV MEEEELAQLR AQQRAFEELR NAELAEAHRL EEQERRHREE KERRKKQHRE
ILLKEKETAE KVAARAFAQQ YLADLVPSVF SSLRDNGYFY DPVERDVETT FMPWLMEEVE
NIMKKNDLGR TMLDMIIRDV VKKRLADFQR ATSQDYLKYE VNSQGQEIKS EKSVMQPQNP
DTEAKHPELQ LKDPETEHKD EILSDI
//
