ID F7APT5_MONDO Unreviewed; 2502 AA.
AC F7APT5;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 3.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB {ECO:0000313|Ensembl:ENSMODP00000001770.4};
GN Name=BDP1 {ECO:0000313|Ensembl:ENSMODP00000001770.4};
OS Monodelphis domestica (Gray short-tailed opossum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Didelphimorphia; Didelphidae; Monodelphis.
OX NCBI_TaxID=13616 {ECO:0000313|Ensembl:ENSMODP00000001770.4, ECO:0000313|Proteomes:UP000002280};
RN [1] {ECO:0000313|Ensembl:ENSMODP00000001770.4, ECO:0000313|Proteomes:UP000002280}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=17495919; DOI=10.1038/nature05805;
RA Mikkelsen T.S., Wakefield M.J., Aken B., Amemiya C.T., Chang J.L., Duke S.,
RA Garber M., Gentles A.J., Goodstadt L., Heger A., Jurka J., Kamal M.,
RA Mauceli E., Searle S.M., Sharpe T., Baker M.L., Batzer M.A., Benos P.V.,
RA Belov K., Clamp M., Cook A., Cuff J., Das R., Davidow L., Deakin J.E.,
RA Fazzari M.J., Glass J.L., Grabherr M., Greally J.M., Gu W., Hore T.A.,
RA Huttley G.A., Kleber M., Jirtle R.L., Koina E., Lee J.T., Mahony S.,
RA Marra M.A., Miller R.D., Nicholls R.D., Oda M., Papenfuss A.T., Parra Z.E.,
RA Pollock D.D., Ray D.A., Schein J.E., Speed T.P., Thompson K.,
RA VandeBerg J.L., Wade C.M., Walker J.A., Waters P.D., Webber C.,
RA Weidman J.R., Xie X., Zody M.C., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Bloom T., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., MacCallum I., Graves J.A., Ponting C.P., Breen M.,
RA Samollow P.B., Lander E.S., Lindblad-Toh K.;
RT "Genome of the marsupial Monodelphis domestica reveals innovation in non-
RT coding sequences.";
RL Nature 447:167-177(2007).
RN [2] {ECO:0000313|Ensembl:ENSMODP00000001770.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_007486561.1; XM_007486499.2.
DR STRING; 13616.ENSMODP00000001770; -.
DR Ensembl; ENSMODT00000001808.4; ENSMODP00000001770.4; ENSMODG00000001460.4.
DR GeneID; 100011617; -.
DR KEGG; mdo:100011617; -.
DR CTD; 55814; -.
DR eggNOG; KOG2009; Eukaryota.
DR GeneTree; ENSGT00390000012762; -.
DR HOGENOM; CLU_000736_0_0_1; -.
DR InParanoid; F7APT5; -.
DR OMA; KNDISPR; -.
DR OrthoDB; 152023at2759; -.
DR TreeFam; TF328878; -.
DR Proteomes; UP000002280; Chromosome 3.
DR Bgee; ENSMODG00000001460; Expressed in skeleton of lower jaw and 17 other cell types or tissues.
DR GO; GO:0000126; C:transcription factor TFIIIB complex; IBA:GO_Central.
DR GO; GO:0001156; F:TFIIIC-class transcription factor complex binding; IBA:GO_Central.
DR GO; GO:0070898; P:RNA polymerase III preinitiation complex assembly; IBA:GO_Central.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR039467; TFIIIB_B''_Myb.
DR PANTHER; PTHR22929; RNA POLYMERASE III TRANSCRIPTION INITIATION FACTOR B; 1.
DR PANTHER; PTHR22929:SF0; TRANSCRIPTION FACTOR TFIIIB COMPONENT B'' HOMOLOG; 1.
DR Pfam; PF15963; Myb_DNA-bind_7; 1.
DR SMART; SM00717; SANT; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000002280}.
FT DOMAIN 304..352
FT /note="Myb-like"
FT /evidence="ECO:0000259|SMART:SM00717"
FT REGION 1..149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 162..185
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 200..245
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 384..436
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 464..500
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 563..582
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 638..847
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 909..975
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 989..1151
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1284..1307
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1375..1395
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1573..1592
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1661..1694
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1709..1739
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1940..1986
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2060..2090
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2424..2484
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1748..1775
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 27..65
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..81
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 87..131
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 208..229
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 230..244
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 384..398
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 408..433
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 660..701
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 723..749
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 750..771
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 772..787
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 791..807
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 931..945
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 958..975
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1001..1060
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1076..1092
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1099..1113
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1123..1151
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1668..1694
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1718..1738
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1940..1972
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2073..2090
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2447..2466
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2467..2484
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2502 AA; 276386 MW; 13E1AE0C33D1FA88 CRC64;
MFRRARLSVK PNVRPGAGGR GPAAPEPPRG QQVPREPEPA APLPPVPAPE AAAILPGPPP
DPGLAEPLED EVVECGDEKP AEDDVGESSK SSPTSLQRRK QISTASSLTK SSDPVQSTPQ
SSCTVQQEAL QPSPLPGKEK QQCSDRYRML KAQKLREMLR EEMTKRRKQW KNKYAGNENQ
MPPDRSKMTM RDLIYYLPDS NPMKSSLEQE AKTEKSTPVQ TKEQEEKNIP DAEGDDEEME
EENNDGPLLV PRVKVAEDGS IILDEESLTV EVLRTKGPCV VEENDPIFER GSTTTYSSFR
KNYYSKPWSN KETDMFFLAI SMVGTDFSMI GQLFPHRARI EIKNKFKREE KANGWRIDKA
FQEKRPFDFN FFARLLEKVL AEEEKRKQKT VKNQNAKEKK SSRSRKKQNV NRVASGEVND
QPDDTLNTRT SDTEGTEIDA EIVEKENDQS LNVAGQTVLE SVVNRKKRKR KKKDDTDEQE
AENLSKGSAD LSETSKGEKP NKKKCQLLVA VINKDECNKD LEVSNFENVG EIPCISLSEN
SENDTEHISS ARNQNDNAAA IAAGESSGPE ASDLSSSKAK SKELTQIIQI DSNIEGKMSD
TNVKLLEAEK ADTSNLQVRG HPLKPKPNLL RTFGKKAEAT KSKIEAESKN SFPELPGNVK
KNLMEKDECY PPVSTGKEVK ETENQEPEDE FHEKHGLQET EKASTFRPPR LMRGQMQKPK
PHIGKPNDQK EVVAAEIKNG TKGEKYERES SVPQGTQIQT EDQSFNKLDV GNSRPQHEKE
DVVSQLSKTD EPEAVMENQS LQDGNKLSTF KEGPVRRARF QKPRPNVGRA TGRSEISPRE
KASKEISVTG KVEAGLLQTD GEFNSLPLPN NINCGLPSLV EEFEKEASSQ KGISSPVIPL
KPSCISPSEE CEKDKEIQPT ADLEQVPDVS KSKCPQDEKL SVAKKPPFVR SRFKRPRPNL
RRAIEKGGAP GAEKCELLKK LETEKLEIMI QHDDRNQDAI SSPQDHASSL QDKVSPFCQD
DSFPPQVTSF SQVDASSPKD DSVPLQDDCS SPQVTASFPQ VDASFPKDDS IPLQDDSFPP
QVTASCPQVD ASFPKDNYTL AQVADSSPQD PASPPHLDTS PPQDSASPPQ VNAFPLQDEV
SSLQDDTSSL QEDAYPLQVI ASSLQVDASS SQDNASPLQV NIFPAQVCTS PHRLAVSPFQ
VEASFQDNAS PPRVSVFPTQ ICASPQLAAS PLQVIASPLQ VDVPASQDNA SPPQVSVFPA
QVYASTVQLA ASPLQVITSS YQDDVSTPQD NAFPPQMTAS PAQDDASSLQ NDASLLQVVV
SPLQDSVPTT QVDASPTQVI TSPAEDDESP VQVATCQSQA DAFPIADVNH LCQNDTTESS
QKSAINHEDP GPEKGVEDLL LKEQTPKKLL DSLNCELEEP FIGAQENDFA VSTGIQNSQQ
EIKKNDIQPL RMRGRLKRPR PNISKVERRG SRLAGKCVVE ERAKEEGIIL HKNESESESF
TLPSSKIESE VVPFEVCESK NQGVSEENLQ VSRTEVLKEQ ISKEKYKLHT VSPAQFRRCR
FQTVKPNLER ACRKKEEPDT EKIVPNKNDT RRAEDKLLQQ EDSDTHQSLK DKTELLSSLG
IAQRKEHGDS RDFALPKEYS QSEKLDSFDR QLECSCDSGP GATLSSVGVE EQFPNKSTRH
TQQSKEPSCL KNTLGRRIVT SSISECEMDN SDRRIHRKSK QNFSKGRGSK RVRARISRKE
PRTSKAVLVT LRASQEEDEE DLEDLESEYE EENYHLAPEE VNKAPVFVPI GLRSPEPVSA
QIEETMEELE ISVNVPDVPC ITIADHLLPN VNMSNEEVNQ KENLNASVEL ATIEYSEEKT
GNSDGSTEAA IALLTMGGQM LQSEMDTAGI VCVLPEDDLR SNTSNPETFD HRVVLEQQVI
SSPGPSTLLT SLDENKITLE EQNTGKEVNI PGQIKENSIP SSDQSSKKTS SLRTRSRFPK
PKPNLSKILG KDRHVRQKLT SFPTTVDQQV DIQCETECSA SKGAELEDIN LESKIKTDIQ
TGKLTDLCSI ECTNDGKEVN EFQSEENQDK ESQESQMVSA SPLATTSSHD SNYNLAEMPI
GEFLSSGNDK HNLLMTHFAQ ECRLNTATEV EQQNVISPDD PTVNQVDSEH RGEEEEQTVI
LTLVEIPTDS EEQFAGTSDL LLIGPLLPAP ILVKSTNKEE RGDLSLNFPF GEDVTQLSNY
GISVQPSPEK SPTDMDLTLS KTLGCSLEKS NSLIAPTEPS VSTSGEDCQT IISEVCSDEL
ISMHKNAAGE PYEKQTVVPI LGSTCTIAEP QETQKEPSET SVQGSGTVSC VEVTCTEKEE
DAPHLPQDEV VISDKHERTG ATYQLEQSSK PSSLLSRPGR RPLGFLSLIC SKNNLESEEA
TPMNNQKRLK PLIPISRRNI KRPVLLNEGK RKKQDSCPLP PASAETHSEA GTVSSSTPQV
SCDQSVEEES CKSDQKMETE EEPTKVAEYF FSDIFMEVDE TQ
//
