ID F7ARI0_MACMU Unreviewed; 905 AA.
AC F7ARI0;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 3.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=PPFIA binding protein 2 {ECO:0000313|Ensembl:ENSMMUP00000025971.4};
GN Name=PPFIBP2 {ECO:0000313|Ensembl:ENSMMUP00000025971.4,
GN ECO:0000313|VGNC:VGNC:76238};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|Ensembl:ENSMMUP00000025971.4, ECO:0000313|Proteomes:UP000006718};
RN [1] {ECO:0000313|Proteomes:UP000006718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=17573 {ECO:0000313|Proteomes:UP000006718};
RX PubMed=17431167; DOI=10.1126/science.1139247;
RA Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M.,
RA Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C., Wilson R.K.,
RA Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W., Hardison R.C.,
RA Makova K.D., Miller W., Milosavljevic A., Palermo R.E., Siepel A.,
RA Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J.,
RA Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y., Dinh H.H.,
RA Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T., Godfrey J.,
RA Hawes A.C., Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N.,
RA Joshi V., Khan Z.M., Kirkness E.F., Cree A., Fowler R.G., Lee S.,
RA Lewis L.R., Li Z., Liu Y.-S., Moore S.M., Muzny D., Nazareth L.V.,
RA Ngo D.N., Okwuonu G.O., Pai G., Parker D., Paul H.A., Pfannkoch C.,
RA Pohl C.S., Rogers Y.-H.C., Ruiz S.J., Sabo A., Santibanez J.,
RA Schneider B.W., Smith S.M., Sodergren E., Svatek A.F., Utterback T.R.,
RA Vattathil S., Warren W., White C.S., Chinwalla A.T., Feng Y., Halpern A.L.,
RA Hillier L.W., Huang X., Minx P., Nelson J.O., Pepin K.H., Qin X.,
RA Sutton G.G., Venter E., Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P.,
RA Jones S.M., Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L.,
RA Csuros M., Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H.,
RA Liu Y., Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E.,
RA Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J.,
RA Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J.,
RA Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A.,
RA Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J., Denby A.,
RA Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A., Marklein A.,
RA Nielsen R., Vallender E.J., Clark A.G., Ferguson B., Hernandez R.D.,
RA Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S., Pu L.-L., Ren Y.,
RA Smith D.G., Wheeler D.A., Schenck I., Ball E.V., Chen R., Cooper D.N.,
RA Giardine B., Hsu F., Kent W.J., Lesk A., Nelson D.L., O'brien W.E.,
RA Pruefer K., Stenson P.D., Wallace J.C., Ke H., Liu X.-M., Wang P.,
RA Xiang A.P., Yang F., Barber G.P., Haussler D., Karolchik D., Kern A.D.,
RA Kuhn R.M., Smith K.E., Zwieg A.S.;
RT "Evolutionary and biomedical insights from the rhesus macaque genome.";
RL Science 316:222-234(2007).
RN [2] {ECO:0000313|Ensembl:ENSMMUP00000025971.4}
RP IDENTIFICATION.
RC STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000025971.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the liprin family. Liprin-beta subfamily.
CC {ECO:0000256|ARBA:ARBA00007547}.
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DR AlphaFoldDB; F7ARI0; -.
DR SMR; F7ARI0; -.
DR Ensembl; ENSMMUT00000027762.4; ENSMMUP00000025971.4; ENSMMUG00000019751.4.
DR VEuPathDB; HostDB:ENSMMUG00000019751; -.
DR VGNC; VGNC:76238; PPFIBP2.
DR eggNOG; KOG1899; Eukaryota.
DR GeneTree; ENSGT01050000244951; -.
DR HOGENOM; CLU_011689_2_1_1; -.
DR TreeFam; TF314207; -.
DR Proteomes; UP000006718; Chromosome 14.
DR Bgee; ENSMMUG00000019751; Expressed in adipose tissue and 22 other cell types or tissues.
DR ExpressionAtlas; F7ARI0; baseline and differential.
DR CDD; cd09563; SAM_liprin-beta1_2_repeat1; 1.
DR CDD; cd09566; SAM_liprin-beta1_2_repeat2; 1.
DR CDD; cd09569; SAM_liprin-beta1_2_repeat3; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 3.
DR InterPro; IPR029515; Liprin.
DR InterPro; IPR037617; Liprin-beta_SAM_rpt_1.
DR InterPro; IPR037618; Liprin-beta_SAM_rpt_2.
DR InterPro; IPR037619; Liprin-beta_SAM_rpt_3.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR PANTHER; PTHR12587; LAR INTERACTING PROTEIN LIP -RELATED PROTEIN; 1.
DR PANTHER; PTHR12587:SF18; LIPRIN-BETA-2; 1.
DR Pfam; PF00536; SAM_1; 2.
DR Pfam; PF07647; SAM_2; 1.
DR SMART; SM00454; SAM; 3.
DR SUPFAM; SSF47769; SAM/Pointed domain; 3.
DR PROSITE; PS50105; SAM_DOMAIN; 3.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000006718};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 574..638
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 651..709
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 734..765
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 423..453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 468..515
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 542..569
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 856..905
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 104..131
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 181..260
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 484..506
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 905 AA; 101357 MW; 4734C4CDB7ACBA95 CRC64;
MASDASHALE AALEQMDGII AGTKTGADLS DGTCEPGLAS PASYMNSFPV LHLIEDLRLA
LEMLELPQER AALLSQIPGP TAAYIKEWFE ESLSQVNHHS AASNETYQER LARLEGDKES
LILQVSVLTD QVEAQGEKIR DLEVCLEGHQ VKLNAAEEML QQELLSRTSL ETQKLDLMTE
VSELKLKLVG MEKEQREQEE KQRKAEELLQ ELRHLKIKVE ELENERNQYE WKLKATKAEV
AQLQEQVALK DAEIERLHSQ LSRTAALHGD HTERDQEIQR LKMGMETLLL ANEDKDRRIE
ELTGLLNQYR KVKEIVVVTQ GPSERTLSIN EEELEGGFRK WNTTNKGPEE LFKQEMPPRC
SSPTAGPPPL PQKSLEARAQ KKLSCSLEDL RSESMDKCMD GNQPFPVVEP KDSPFLAEHK
YPTLPGKLSG PMPNGEAAKS PPTVCQPDAT GSSLLRLNRG RSVSAPVLGT VPIPGDTESG
WDDTAVVNDL SSTSSGTESG PQSPLTPDGK RNPKGIKKFW GKIRRTQSGN FNTDTLGMAE
FRRGGLRATA GPRLSRTRDS KGQKSDANAP FAQWSTERVC AWLEDFGLAQ YVIFARQWVS
SGHTLLTATP QDMEKELGIK HPLHRKKLVL AVKAINTKQE EKSALLDHIW VTRWLDDIGL
PQYKDQFHES RVDGRMLQYL TVNDLLFLKV TSQLHHLSIK CAIHVLHVNK FNPHCLHRRP
ADESNLSPSE VVQWSNHRVM EWLRSVDLAE YAPNLRGSGV HGGLIILEPR FTGDTLAMLL
NIPPQKTLLR RHLTTKFNAL IGPEAEQEKR EKMASPAYTP LTTTAKVRPR KLGFSHFGNI
RKKKFDESTD YICPMEPSDG VSDSHRVYSG YRDLSPLDAP ELDGLDQKRS NTRKAPPGPS
CCSLD
//
