ID F7ASD1_HORSE Unreviewed; 247 AA.
AC F7ASD1;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2023, sequence version 4.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=DCN1-like protein {ECO:0000256|RuleBase:RU363131};
DE AltName: Full=Defective in cullin neddylation protein 1-like protein {ECO:0000256|RuleBase:RU363131};
GN Name=DCUN1D2 {ECO:0000313|Ensembl:ENSECAP00000004064.4,
GN ECO:0000313|VGNC:VGNC:17063};
OS Equus caballus (Horse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000004064.4, ECO:0000313|Proteomes:UP000002281};
RN [1] {ECO:0000313|Ensembl:ENSECAP00000004064.4, ECO:0000313|Proteomes:UP000002281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000004064.4,
RC ECO:0000313|Proteomes:UP000002281};
RX PubMed=19892987; DOI=10.1126/science.1178158;
RG Broad Institute Genome Sequencing Platform;
RG Broad Institute Whole Genome Assembly Team;
RA Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
RA Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O.,
RA Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.,
RA Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T.,
RA Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S.,
RA Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G.,
RA Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R.,
RA Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A.,
RA Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J.,
RA Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
RT "Genome sequence, comparative analysis, and population genetics of the
RT domestic horse.";
RL Science 326:865-867(2009).
RN [2] {ECO:0000313|Ensembl:ENSECAP00000004064.4}
RP IDENTIFICATION.
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000004064.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F7ASD1; -.
DR STRING; 9796.ENSECAP00000004064; -.
DR PaxDb; 9796-ENSECAP00000004064; -.
DR Ensembl; ENSECAT00000005761.4; ENSECAP00000004064.4; ENSECAG00000005413.4.
DR VGNC; VGNC:17063; DCUN1D2.
DR GeneTree; ENSGT00940000157453; -.
DR HOGENOM; CLU_047042_0_1_1; -.
DR InParanoid; F7ASD1; -.
DR OMA; NPDAYYK; -.
DR TreeFam; TF313332; -.
DR Proteomes; UP000002281; Chromosome 17.
DR Bgee; ENSECAG00000005413; Expressed in muscle tissue and 23 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR GO; GO:0000151; C:ubiquitin ligase complex; IBA:GO_Central.
DR GO; GO:0097602; F:cullin family protein binding; IBA:GO_Central.
DR GO; GO:0031624; F:ubiquitin conjugating enzyme binding; IBA:GO_Central.
DR GO; GO:0032182; F:ubiquitin-like protein binding; IBA:GO_Central.
DR GO; GO:2000436; P:positive regulation of protein neddylation; IEA:Ensembl.
DR GO; GO:0045116; P:protein neddylation; IBA:GO_Central.
DR Gene3D; 1.10.238.200; Cullin, PONY binding domain; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR014764; DCN-prot.
DR InterPro; IPR042460; DCN1-like_PONY.
DR InterPro; IPR005176; PONY_dom.
DR PANTHER; PTHR12281:SF16; DCN1-LIKE PROTEIN 2; 1.
DR PANTHER; PTHR12281; RP42 RELATED; 1.
DR Pfam; PF03556; Cullin_binding; 1.
DR Pfam; PF14555; UBA_4; 1.
DR PROSITE; PS51229; DCUN1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002281}.
FT DOMAIN 45..233
FT /note="DCUN1"
FT /evidence="ECO:0000259|PROSITE:PS51229"
SQ SEQUENCE 247 AA; 28488 MW; DFD99E4BC85449DE CRC64;
MAFTQTGERT AIYCLTQNEW KLDLATDTFF QNPDSFHQDS MRNTVDKKKL EQLYSRYKDP
QDENKIGIDG IQQFCEDLSL DPASVSALVI AWKFRAATQC EFSKKEFVDG MTELGCDSTD
KLKALLPRLE QELKDAVKFK DFYQFTFSFA KNPGQKGLDL EMAIAYWNLV LSGRFKFLDL
WNTFLLEHHK RSIPRDTWNL LLDFGNMIAD DMSNYDEEGA WPVLIDDFVE YARPVVTGGK
HSGGLRL
//
