ID F7ATV5_HORSE Unreviewed; 353 AA.
AC F7ATV5;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2023, sequence version 3.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=RAD51 paralog B {ECO:0000313|Ensembl:ENSECAP00000011815.3};
GN Name=RAD51B {ECO:0000313|Ensembl:ENSECAP00000011815.3,
GN ECO:0000313|VGNC:VGNC:55308};
OS Equus caballus (Horse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000011815.3, ECO:0000313|Proteomes:UP000002281};
RN [1] {ECO:0000313|Ensembl:ENSECAP00000011815.3, ECO:0000313|Proteomes:UP000002281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000011815.3,
RC ECO:0000313|Proteomes:UP000002281};
RX PubMed=19892987; DOI=10.1126/science.1178158;
RG Broad Institute Genome Sequencing Platform;
RG Broad Institute Whole Genome Assembly Team;
RA Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
RA Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O.,
RA Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.,
RA Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T.,
RA Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S.,
RA Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G.,
RA Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R.,
RA Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A.,
RA Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J.,
RA Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
RT "Genome sequence, comparative analysis, and population genetics of the
RT domestic horse.";
RL Science 326:865-867(2009).
RN [2] {ECO:0000313|Ensembl:ENSECAP00000011815.3}
RP IDENTIFICATION.
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000011815.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F7ATV5; -.
DR Ensembl; ENSECAT00000014765.4; ENSECAP00000011815.3; ENSECAG00000014132.4.
DR VGNC; VGNC:55308; RAD51B.
DR GeneTree; ENSGT00940000160169; -.
DR HOGENOM; CLU_013059_0_0_1; -.
DR TreeFam; TF101219; -.
DR Proteomes; UP000002281; Chromosome 24.
DR Bgee; ENSECAG00000014132; Expressed in trophectoderm and 23 other cell types or tissues.
DR ExpressionAtlas; F7ATV5; baseline.
DR GO; GO:0033063; C:Rad51B-Rad51C-Rad51D-XRCC2 complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0000724; P:double-strand break repair via homologous recombination; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR013632; DNA_recomb/repair_Rad51_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR030548; RAD51B.
DR InterPro; IPR020588; RecA_ATP-bd.
DR PANTHER; PTHR46456; DNA REPAIR PROTEIN RAD51 HOMOLOG 2; 1.
DR PANTHER; PTHR46456:SF1; DNA REPAIR PROTEIN RAD51 HOMOLOG 2; 1.
DR Pfam; PF08423; Rad51; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50162; RECA_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002281}.
FT DOMAIN 79..259
FT /note="RecA family profile 1"
FT /evidence="ECO:0000259|PROSITE:PS50162"
SQ SEQUENCE 353 AA; 38812 MW; F5DC7C405E0E562F CRC64;
MGSKKLRRVG LSQELCDRLS RHQIVTCRDF LCLSPLELMK MTGLSYRGVH ELLCMVSRAC
APQMQTAYGI KTQRSAALSP AFLPTTLSAL DEALHGGVAC GSLTEITGPP GCGKTQFCIM
MSILATLPID MGGLEGAVVY IDTEAAFSAE RLVEIAESRF PSYFNNEDKL LLTSSNVHLY
RELSCDEVLQ RVESLEEEII SKGVKLVIID SVASVVRKEF DTQLQGNMRE RNKFLAREAA
SLKYLAEEFS IPHGFCQAVP CPRLASELVN TGPRRSRMCK LNCCATGPAQ NNSILSAVLL
AAMCLVFPYR PLFILAVDVL PFHLSLSKFY SSFTSELASS VSSQRFVYHS VLA
//
