ID F7AXD2_XENTR Unreviewed; 917 AA.
AC F7AXD2;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 4.
DT 27-MAR-2024, entry version 73.
DE RecName: Full=SRCR domain-containing protein {ECO:0000259|PROSITE:PS50287};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|Ensembl:ENSXETP00000015486};
RN [1] {ECO:0000313|Ensembl:ENSXETP00000015486}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000015486};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [2] {ECO:0000313|Ensembl:ENSXETP00000015486}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUN-2011) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00196}.
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DR AlphaFoldDB; F7AXD2; -.
DR Ensembl; ENSXETT00000015486; ENSXETP00000015486; ENSXETG00000033748.
DR AGR; Xenbase:XB-GENE-920672; -.
DR eggNOG; ENOG502QQ5W; Eukaryota.
DR HOGENOM; CLU_258459_0_0_1; -.
DR OrthoDB; 4250502at2759; -.
DR TreeFam; TF329295; -.
DR Bgee; ENSXETG00000033748; Expressed in neurula embryo and 1 other cell type or tissue.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR Gene3D; 3.10.250.10; SRCR-like domain; 9.
DR InterPro; IPR001190; SRCR.
DR InterPro; IPR017448; SRCR-like_dom.
DR InterPro; IPR036772; SRCR-like_dom_sf.
DR PANTHER; PTHR48071:SF24; SCAVENGER RECEPTOR CYSTEINE-RICH TYPE 1 PROTEIN M130-RELATED; 1.
DR PANTHER; PTHR48071; SRCR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00530; SRCR; 9.
DR PRINTS; PR00258; SPERACTRCPTR.
DR SMART; SM00202; SR; 8.
DR SUPFAM; SSF56487; SRCR-like; 9.
DR PROSITE; PS00420; SRCR_1; 3.
DR PROSITE; PS50287; SRCR_2; 9.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00196}.
FT DOMAIN 1..87
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 93..192
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 197..297
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 296..393
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 387..486
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 492..593
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 598..697
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 702..789
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 795..895
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DISULFID 12..76
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 25..86
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 56..66
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 161..171
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 222..286
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 235..296
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 266..276
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 362..372
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 455..465
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 560..570
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 666..676
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 771..781
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 820..884
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 833..894
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 864..874
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
SQ SEQUENCE 917 AA; 100510 MW; 8A1571C59F29AD9F CRC64;
EVYLRGEWGT VCSDDWGTRD ADVVCRQLGC GRAVSATTNA HHGAGTGRIW LDDVRCRGTE
SYLWECDSRP WGEHDCNHGW DAGVICSVRS DLLRLRNGTS PCEGKVEVSH QGEWGTVCGN
NWDTNDADVV CRQLGCGRAV RATNAHHGAG TGRIWLDNVR CRGNESYLWE CDSRPWGEHN
CNHVEHAGVI CSGYKTLQLQ NGTSPCEGRV EVYLRGEWGT VCSAGWDTDD ADVVCRQLGC
GRAVSATTNA HHGAGTGRIW LANVLCRGNE SYLWECDSRP WGEHNCNHGW DAGVICSGDV
SDAIAANISK FILASVCELD AELRAANVIC RQLNCGSAVT PPVITNSYER RTEKIWTEEI
RCIGNETNVL DCFWINSAEK NCSNPNLPTV HCTGDCSGRV ELGRVGQWGS LCNSHWDLHA
ANVLCRQLYC GTAVSVPHGN MFGTSNLTWT DRFHCKGTES QLAECPYTAL GNSDCPHGET
AAVICTGRKE TLRLMGGESH CEGRVEVQNG SWHRVYGSEW GIEEAQVVCR ELHCGEAVSA
FTSEAQLPDS SHGIWESIKC NGNESQLQDC VGTQASSVAQ GCDPKKDVGV ICSASRRVRL
VDGRGRCAGR VEVYHHGEWG TVCDDSWDVE DANVVCRQLR CGHAISTTNA FHGSGTGKIW
MDDLKCLGNE TSLWDCPSSP WGLHNCQHKE DVGVICSEFT DLRLVGGTHE CEGRVEVYYN
GSWTSVCNNA MEETTASLIC NQLNCGVSNE SVSLYEYGVA QGPFLLDNIK CRKNDAALWQ
CSSKPWTRNI YSERIRLIGG QDKCSGRVEV FYQGAWGTVC DDSWDRKDAE VVCAQLGCGS
AINATGEAMF GSGTGPIWLD EVSCKGHEQA LQDCFSVRWN RSDCHHKEDA GVICTVGLTC
KENTRNILHT LQYHDST
//
