ID F7AZB8_CIOIN Unreviewed; 648 AA.
AC F7AZB8;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 2.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=ATPase AAA-type core domain-containing protein {ECO:0000259|Pfam:PF00004};
OS Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis).
OC Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
OC Cionidae; Ciona.
OX NCBI_TaxID=7719 {ECO:0000313|Ensembl:ENSCINP00000019219.3, ECO:0000313|Proteomes:UP000008144};
RN [1] {ECO:0000313|Proteomes:UP000008144}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12481130; DOI=10.1126/science.1080049;
RA Dehal P., Satou Y., Campbell R.K., Chapman J., Degnan B., De Tomaso A.,
RA Davidson B., Di Gregorio A., Gelpke M., Goodstein D.M., Harafuji N.,
RA Hastings K.E., Ho I., Hotta K., Huang W., Kawashima T., Lemaire P.,
RA Martinez D., Meinertzhagen I.A., Necula S., Nonaka M., Putnam N., Rash S.,
RA Saiga H., Satake M., Terry A., Yamada L., Wang H.G., Awazu S., Azumi K.,
RA Boore J., Branno M., Chin-Bow S., DeSantis R., Doyle S., Francino P.,
RA Keys D.N., Haga S., Hayashi H., Hino K., Imai K.S., Inaba K., Kano S.,
RA Kobayashi K., Kobayashi M., Lee B.I., Makabe K.W., Manohar C., Matassi G.,
RA Medina M., Mochizuki Y., Mount S., Morishita T., Miura S., Nakayama A.,
RA Nishizaka S., Nomoto H., Ohta F., Oishi K., Rigoutsos I., Sano M.,
RA Sasaki A., Sasakura Y., Shoguchi E., Shin-i T., Spagnuolo A., Stainier D.,
RA Suzuki M.M., Tassy O., Takatori N., Tokuoka M., Yagi K., Yoshizaki F.,
RA Wada S., Zhang C., Hyatt P.D., Larimer F., Detter C., Doggett N.,
RA Glavina T., Hawkins T., Richardson P., Lucas S., Kohara Y., Levine M.,
RA Satoh N., Rokhsar D.S.;
RT "The draft genome of Ciona intestinalis: insights into chordate and
RT vertebrate origins.";
RL Science 298:2157-2167(2002).
RN [2] {ECO:0000313|Ensembl:ENSCINP00000019219.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the Nav/unc-53 family.
CC {ECO:0000256|ARBA:ARBA00006255}.
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DR EMBL; EAAA01001089; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; F7AZB8; -.
DR STRING; 7719.ENSCINP00000019219; -.
DR Ensembl; ENSCINT00000019219.3; ENSCINP00000019219.3; ENSCING00000009447.3.
DR GeneTree; ENSGT00940000168701; -.
DR HOGENOM; CLU_001002_2_1_1; -.
DR InParanoid; F7AZB8; -.
DR OMA; WIRSSFS; -.
DR Proteomes; UP000008144; Chromosome 13.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0022008; P:neurogenesis; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR039041; Nav/unc-53.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR12784:SF28; PROTEIN SICKIE; 1.
DR PANTHER; PTHR12784; STEERIN; 1.
DR Pfam; PF00004; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000008144}.
FT DOMAIN 393..468
FT /note="ATPase AAA-type core"
FT /evidence="ECO:0000259|Pfam:PF00004"
FT REGION 50..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 171..205
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 50..81
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 98..141
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 648 AA; 72305 MW; CF27A4A6F408D378 CRC64;
QREENELDKL RKTIEELRAK AERSAGNSTA PSPEELACFK FLDALSPNSP INKRISSGSL
SSMSSHASHS SVSSASSGSS GDSDGKHKKK RWLPLKSAFS KSSKTSQSNN SGQEFTDADD
SGCMTSPNSS RRSFRSASTG IGESEESISY NEILQIVQEK DRKLTDVRLE ALTSQHQLHQ
LKDQIAQMQH EMQLLRLENE RLQAGTHVNN GYINSSLSPS SSFHLCMNSI KNSHSCSDCS
KLYRAVSPGS EDEGSQIRFV VETPYTIKFG QNKNEDDILI GSLPVARKTN WAELDQMTGD
LFTEYCRCVD GDSRLGLSIA SIAFYKVGEQ TRIPGSRPPE LLPCAFMVGD VDSVKISLKD
ATCGSVELMA FRSLVPRDTL QRYITSLMHK TRIMLHGPSG TGKTYLAHSL AQHMVARARR
QITSADPVFV YDVKQRGEED LQIYIKKVAE ACKTSAYSTL PYVIIVENNH LLTSLTQTYA
PIVQLPQQAK CPYVIGTILQ GKAHRAEEHR DEFTWISCKN NSAHVKDYLA RFLRKAVVEC
RVGGKETPKD EFQNTLRVIT WLPLCWHQVN RCLEAQCAAD VTIGPRVFAS FPVEFYSSCT
WFVQVWNHVI APYVIAAVRR IRQSAEGTPK PWADPTEWVI DSFPWNAS
//
