ID F7B149_HORSE Unreviewed; 163 AA.
AC F7B149;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 2.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Family with sequence similarity 162 member B {ECO:0000313|Ensembl:ENSECAP00000016638.2};
GN Name=FAM162B {ECO:0000313|Ensembl:ENSECAP00000016638.2,
GN ECO:0000313|VGNC:VGNC:17816};
OS Equus caballus (Horse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000016638.2, ECO:0000313|Proteomes:UP000002281};
RN [1] {ECO:0000313|Ensembl:ENSECAP00000016638.2, ECO:0000313|Proteomes:UP000002281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000016638.2,
RC ECO:0000313|Proteomes:UP000002281};
RX PubMed=19892987; DOI=10.1126/science.1178158;
RG Broad Institute Genome Sequencing Platform;
RG Broad Institute Whole Genome Assembly Team;
RA Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
RA Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O.,
RA Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.,
RA Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T.,
RA Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S.,
RA Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G.,
RA Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R.,
RA Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A.,
RA Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J.,
RA Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
RT "Genome sequence, comparative analysis, and population genetics of the
RT domestic horse.";
RL Science 326:865-867(2009).
RN [2] {ECO:0000313|Ensembl:ENSECAP00000016638.2}
RP IDENTIFICATION.
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000016638.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the UPF0389 family.
CC {ECO:0000256|ARBA:ARBA00007363}.
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DR RefSeq; XP_005596956.1; XM_005596899.2.
DR AlphaFoldDB; F7B149; -.
DR Ensembl; ENSECAT00000020278.4; ENSECAP00000016638.2; ENSECAG00000019150.4.
DR GeneID; 100147458; -.
DR CTD; 221303; -.
DR VGNC; VGNC:17816; FAM162B.
DR GeneTree; ENSGT00640000091497; -.
DR HOGENOM; CLU_122911_1_0_1; -.
DR OMA; KGRGEVH; -.
DR OrthoDB; 2970852at2759; -.
DR TreeFam; TF323771; -.
DR Proteomes; UP000002281; Chromosome 10.
DR Bgee; ENSECAG00000019150; Expressed in testis and 13 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR009432; DUF1075.
DR PANTHER; PTHR13674; GROWTH AND TRANSFORMATION-DEPENDENT PROTEIN; 1.
DR PANTHER; PTHR13674:SF3; PROTEIN FAM162B; 1.
DR Pfam; PF06388; DUF1075; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002281};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 110..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 163 AA; 17809 MW; AB43DDE49AB57241 CRC64;
MLAAVGSLLR FRPGRILHCA PGTPGDAVRW PFAALRSRGL PRYSSDGAPC GSGPQGPAGK
VHRVPAEHKP SQFDKKILLW TGRFKAMEEI PPRVPPEMID AARNRARVKA CYIMIGFTII
ACFAVIASAK RAVERHESLT SWNLAKKAKW REEAALAAQA KAK
//
