ID F7BBA5_CALJA Unreviewed; 544 AA.
AC F7BBA5;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 4.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=Tubby-like protein {ECO:0000256|RuleBase:RU361125};
GN Name=TULP1 {ECO:0000313|Ensembl:ENSCJAP00000046255.4};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000046255.4, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000046255.4}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000046255.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TUB family. {ECO:0000256|ARBA:ARBA00007129,
CC ECO:0000256|RuleBase:RU361125}.
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DR RefSeq; XP_002746512.1; XM_002746466.3.
DR AlphaFoldDB; F7BBA5; -.
DR STRING; 9483.ENSCJAP00000046255; -.
DR Ensembl; ENSCJAT00000061031.4; ENSCJAP00000046255.4; ENSCJAG00000015713.5.
DR GeneTree; ENSGT00940000158771; -.
DR InParanoid; F7BBA5; -.
DR OMA; YAKFIRD; -.
DR OrthoDB; 603296at2759; -.
DR Proteomes; UP000008225; Chromosome 4.
DR GO; GO:0043679; C:axon terminus; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005576; C:extracellular region; IEA:Ensembl.
DR GO; GO:0001917; C:photoreceptor inner segment; IEA:Ensembl.
DR GO; GO:0001750; C:photoreceptor outer segment; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0051015; F:actin filament binding; IEA:Ensembl.
DR GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IEA:Ensembl.
DR GO; GO:0016358; P:dendrite development; IEA:Ensembl.
DR GO; GO:0050908; P:detection of light stimulus involved in visual perception; IEA:Ensembl.
DR GO; GO:0042462; P:eye photoreceptor cell development; IEA:Ensembl.
DR GO; GO:0006910; P:phagocytosis, recognition; IEA:Ensembl.
DR GO; GO:0045494; P:photoreceptor cell maintenance; IEA:Ensembl.
DR GO; GO:0050766; P:positive regulation of phagocytosis; IEA:Ensembl.
DR GO; GO:1903546; P:protein localization to photoreceptor outer segment; IEA:Ensembl.
DR GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR InterPro; IPR025659; Tubby-like_C.
DR InterPro; IPR000007; Tubby_C.
DR InterPro; IPR018066; Tubby_C_CS.
DR PANTHER; PTHR16517; TUBBY-RELATED; 1.
DR PANTHER; PTHR16517:SF12; TUBBY-RELATED PROTEIN 1; 1.
DR Pfam; PF01167; Tub; 1.
DR PRINTS; PR01573; SUPERTUBBY.
DR SUPFAM; SSF54518; Tubby C-terminal domain-like; 1.
DR PROSITE; PS01200; TUB_1; 1.
DR PROSITE; PS01201; TUB_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008225}.
FT DOMAIN 298..538
FT /note="Tubby C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01167"
FT REGION 1..292
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..28
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 92..112
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 113..132
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 133..168
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 175..208
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 243..260
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 544 AA; 60742 MW; 9DE1ADFD96DB5B01 CRC64;
MPLQNETLRE VWASDSGHEE ESLSPEAQRR PKQRPAPAQR LRKKRTEGPE SPCPTGSKPR
KPGAGRRGRP REEPSPDPAE ARAPQTVYAR FLRDPEAKKR DPRETFLVAR APDAEDEEEE
EEEEEDEDDE EKEAEEKKKK ILLPPKKPLK EKSSADLKER RAKAQGLRGD LESPDPTPKP
LRTRNKEAPA GEGTKIRKAK KKGSGEADKD PSGSPASARK SPAALFLVGE GSPAKKALKK
KGTPKGERKE EEEEDKAATV TKNSNQKGKA KGKGKKKAKE ERAPSPPVEV DDPQEFVLQP
APQGRTVRCR LTRDKKGMDR GMYPSYFLHL DTEKKVFLLA GRKRKRSKTA NYLISSDPTN
LSRGGENFIG KLRSNLLGNR FTVFDNGQNP QRGYGTNVAS LRQELAAVIY ETNVLGFRGP
RRMTVIIPGM SAENERVPIR PRNASDGLLV RWQNKTLESL IELHNKPPVW NDDSGSYTLN
FQGRVTQASV KNFQIVHADD PDYIVLQFGR VAEDAFTLDY RYPLCALQAF AIALSSFDGK
LACE
//
