ID F7BDW4_HORSE Unreviewed; 111 AA.
AC F7BDW4;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2023, sequence version 3.
DT 27-MAR-2024, entry version 68.
DE RecName: Full=RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012493};
DE EC=2.7.7.49 {ECO:0000256|ARBA:ARBA00012493};
OS Equus caballus (Horse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000011152.3, ECO:0000313|Proteomes:UP000002281};
RN [1] {ECO:0000313|Ensembl:ENSECAP00000011152.3, ECO:0000313|Proteomes:UP000002281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000011152.3,
RC ECO:0000313|Proteomes:UP000002281};
RX PubMed=19892987; DOI=10.1126/science.1178158;
RG Broad Institute Genome Sequencing Platform;
RG Broad Institute Whole Genome Assembly Team;
RA Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
RA Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O.,
RA Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.,
RA Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T.,
RA Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S.,
RA Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G.,
RA Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R.,
RA Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A.,
RA Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J.,
RA Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
RT "Genome sequence, comparative analysis, and population genetics of the
RT domestic horse.";
RL Science 326:865-867(2009).
RN [2] {ECO:0000313|Ensembl:ENSECAP00000011152.3}
RP IDENTIFICATION.
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000011152.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F7BDW4; -.
DR STRING; 9796.ENSECAP00000011152; -.
DR PaxDb; 9796-ENSECAP00000011152; -.
DR Ensembl; ENSECAT00000013999.3; ENSECAP00000011152.3; ENSECAG00000051690.1.
DR GeneTree; ENSGT01100000263511; -.
DR HOGENOM; CLU_000680_1_1_1; -.
DR InParanoid; F7BDW4; -.
DR TreeFam; TF341604; -.
DR Proteomes; UP000002281; Chromosome 17.
DR Bgee; ENSECAG00000034676; Expressed in trophectoderm and 7 other cell types or tissues.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR000477; RT_dom.
DR PANTHER; PTHR19446:SF435; LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN; 1.
DR PANTHER; PTHR19446; REVERSE TRANSCRIPTASES; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002281}.
FT DOMAIN 9..108
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|Pfam:PF00078"
SQ SEQUENCE 111 AA; 12370 MW; 49411D93C0B3E57B CRC64;
MGKEGKYFNI IKAIYDKPIA NITLNGEKLK AISLRTGTRQ GCPLSPLLFS IVLEVLARAI
WQEKEIKGIQ IGNEEVKFSL FADNMILYID NPKKSIGKLL QVISNYSKVA G
//
