ID F7BN67_XENTR Unreviewed; 448 AA.
AC F7BN67;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 4.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Desmin, gene 2 {ECO:0000313|Ensembl:ENSXETP00000015058};
DE SubName: Full=Vimentin A2 {ECO:0000313|RefSeq:XP_002932207.2};
GN Name=des.2 {ECO:0000313|Ensembl:ENSXETP00000015058,
GN ECO:0000313|RefSeq:XP_002932207.2,
GN ECO:0000313|Xenbase:XB-GENE-919965};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|Ensembl:ENSXETP00000015058};
RN [1] {ECO:0000313|Ensembl:ENSXETP00000015058}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000015058};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [2] {ECO:0000313|Ensembl:ENSXETP00000015058}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUN-2011) to UniProtKB.
RN [3] {ECO:0000313|RefSeq:XP_002932207.2}
RP IDENTIFICATION.
RC STRAIN=Nigerian {ECO:0000313|RefSeq:XP_002932207.2};
RC TISSUE=Liver and blood {ECO:0000313|RefSeq:XP_002932207.2};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_002932207.2; XM_002932161.5.
DR STRING; 8364.ENSXETP00000015058; -.
DR PaxDb; 8364-ENSXETP00000026649; -.
DR Ensembl; ENSXETT00000015058; ENSXETP00000015058; ENSXETG00000006876.
DR GeneID; 100490404; -.
DR KEGG; xtr:100490404; -.
DR AGR; Xenbase:XB-GENE-919965; -.
DR CTD; 100490404; -.
DR Xenbase; XB-GENE-919965; des.2.
DR eggNOG; ENOG502QQXP; Eukaryota.
DR HOGENOM; CLU_012560_7_4_1; -.
DR OMA; NDYRHRY; -.
DR TreeFam; TF330122; -.
DR Proteomes; UP000008143; Chromosome 5.
DR Bgee; ENSXETG00000006876; Expressed in testis and 1 other cell type or tissue.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR006821; Intermed_filament_DNA-bd.
DR PANTHER; PTHR45652; GLIAL FIBRILLARY ACIDIC PROTEIN; 1.
DR PANTHER; PTHR45652:SF11; NOTOCHORD GRANULAR SURFACE-RELATED; 1.
DR Pfam; PF00038; Filament; 1.
DR Pfam; PF04732; Filament_head; 1.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754};
KW Reference proteome {ECO:0000313|Proteomes:UP000008143}.
FT DOMAIN 98..408
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 27..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 102..241
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 313..379
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 41..55
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 448 AA; 51278 MW; D33C951F714E3F81 CRC64;
MSRSPERVSS YRRHFEELDC SSVVKLRVSS PSPPRNRRSA SYSRVTREEN ASCRRTASAT
RRPRSMFVPS FGAQLGPTVD LEAASAANQE YLSTRSSEKQ EMIVLNDRLT KYIERVRDLE
QENASAQCEL DALRSRCYKP SNLRALYEEQ LRELRREAEQ AKLQRDLAVA AKVPVVDQLS
AVKKRYEDAV EARKKAEEDI EAFRPDVDAA TAGRISLEKQ LETLEAEISF LQRVHGEEIE
ELMKQIYNMS TSCDLAFSIP DFAAALRDIQ MEYEAIAAKN LQEMDEWYKN KFVDYSQAST
KHVENVRLYR GDMANCKRSI KSKEMELNAL KNRNAILEAQ VKETQEKNKK EIEELQEKID
KLEDDLKTLK QKIALHLREY QDLLSVKMAL DIEIATYRKL IEGEDSRLGT SVSGIHILSS
LSETLQVSTT QSISKSVERK ESTTVLKS
//
