ID F7BV72_HORSE Unreviewed; 1114 AA.
AC F7BV72;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2023, sequence version 3.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=R3H domain containing 1 {ECO:0000313|Ensembl:ENSECAP00000017308.3};
GN Name=R3HDM1 {ECO:0000313|Ensembl:ENSECAP00000017308.3,
GN ECO:0000313|VGNC:VGNC:22081};
OS Equus caballus (Horse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000017308.3, ECO:0000313|Proteomes:UP000002281};
RN [1] {ECO:0000313|Ensembl:ENSECAP00000017308.3, ECO:0000313|Proteomes:UP000002281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000017308.3,
RC ECO:0000313|Proteomes:UP000002281};
RX PubMed=19892987; DOI=10.1126/science.1178158;
RG Broad Institute Genome Sequencing Platform;
RG Broad Institute Whole Genome Assembly Team;
RA Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
RA Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O.,
RA Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.,
RA Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T.,
RA Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S.,
RA Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G.,
RA Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R.,
RA Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A.,
RA Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J.,
RA Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
RT "Genome sequence, comparative analysis, and population genetics of the
RT domestic horse.";
RL Science 326:865-867(2009).
RN [2] {ECO:0000313|Ensembl:ENSECAP00000017308.3}
RP IDENTIFICATION.
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000017308.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F7BV72; -.
DR STRING; 9796.ENSECAP00000017308; -.
DR PaxDb; 9796-ENSECAP00000017308; -.
DR Ensembl; ENSECAT00000021039.3; ENSECAP00000017308.3; ENSECAG00000019114.4.
DR VGNC; VGNC:22081; R3HDM1.
DR GeneTree; ENSGT00940000156095; -.
DR HOGENOM; CLU_007817_0_0_1; -.
DR InParanoid; F7BV72; -.
DR OMA; ACYCAPS; -.
DR OrthoDB; 91945at2759; -.
DR Proteomes; UP000002281; Chromosome 18.
DR Bgee; ENSECAG00000019114; Expressed in trophectoderm and 23 other cell types or tissues.
DR ExpressionAtlas; F7BV72; baseline.
DR GO; GO:0003676; F:nucleic acid binding; IEA:UniProtKB-UniRule.
DR CDD; cd02642; R3H_encore_like; 1.
DR Gene3D; 3.30.1370.50; R3H-like domain; 1.
DR InterPro; IPR001374; R3H_dom.
DR InterPro; IPR036867; R3H_dom_sf.
DR InterPro; IPR024771; SUZ.
DR PANTHER; PTHR15672; CAMP-REGULATED PHOSPHOPROTEIN 21 RELATED R3H DOMAIN CONTAINING PROTEIN; 1.
DR PANTHER; PTHR15672:SF12; R3H DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF01424; R3H; 1.
DR Pfam; PF12752; SUZ; 1.
DR SMART; SM00393; R3H; 1.
DR SUPFAM; SSF82708; R3H domain; 1.
DR PROSITE; PS51061; R3H; 1.
DR PROSITE; PS51673; SUZ; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000002281}.
FT DOMAIN 147..211
FT /note="R3H"
FT /evidence="ECO:0000259|PROSITE:PS51061"
FT DOMAIN 212..282
FT /note="SUZ"
FT /evidence="ECO:0000259|PROSITE:PS51673"
FT REGION 110..146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 247..272
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 311..350
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 367..419
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 470..516
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 598..638
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 954..988
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 110..141
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 494..514
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 600..625
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1114 AA; 122129 MW; 6392D43E5C2A9529 CRC64;
MRMSDTVTVK NETETMKDLE AEVKDTTRVE NLIKSENYGK ILAEKNERCI DNNIDLQRPL
QPFGQTGKRS KSSSKLKLVR SLAVCEESPP PPTAEISQEN QEKIQIQLTQ SFEKEEKPSK
DEAEKEKASD KLPRKMLSRD SSQEYTDSTG IDLHEFLVNT LKNNPRSPRK KFPPMTSYHR
MLLHRVAAYF GLDHNVDQSG KSVIVNKTSN TRIPDQKFNE HIKDDKGEDF QKRYILKRDN
SSFDKDDNQM RIRLKDDRRS KSIEEREEEY QRARDRIFSQ DSLCSQENYI IDKRLQDEDA
SSTQQRRQIF RVNKDASGRS ANSHQSSTEN ELKYSEPRPW SSTDSDSSLR NFKPAVTKAS
SFSGISVLTR GDSSGSSKSI GRLSKTGSES SGSVGSSTGS LSHIQQPLPG TALSQSSHGA
PVVYPTVSTH SSLSFDGGLN GQVAPPSTSF FLLPLEAAGI PPGSILINPQ TGQPFINPDG
SPVVYNPPMT QQPVRTQVPG PPQPPLPPPP PQQQAANHIF SQPVRPLQPS SQPVQCSAVP
YPSPLLPVSP TQQYSVDNLG SQFSHMSLAR QPSADGSDPH ATMFQSTVVL QSPQQSGYIM
TAAPPPPPPP PPPPPPPPLP PGQPVPTAGY SASGHPVSQP VLQQQGYIQQ PSPQMPACYC
APGHYHSSQP QYRPLPSVHY NSHLNQALPQ PAQQTGYQVM PNQQQNYQGI IGVQQPQSQS
LVGGQPNSIG NQIQGVVIPY PSVPSYQVSL PQGSQGIAHQ TYQQPVMFPN QSNQGSMPTT
GMPVYYSVIP PGQQNNLSSS VGYLQHPGSD QVQFPRTTSP CNSQQLQSHQ CAAVPPLPPG
GGMVMMQLSV PNNPQSRAHS PPQWKQNKYY CDHQRGQKCV EFSNVDNIIQ HSPQLSSPIV
SPAQSPAPAQ LSTLKTVRPS GPPLSIIPQF SRPFVPGQGD ARYPLLGQPL QYNPPAVLHG
HIPTQQGQSG SRHGNRGRKQ AKKAASTDLG AGEAVVGKVL EITELPDGIT RMEAEKLFGE
LFKIGAKIRW LRDPQSQPPL RRHPLCCGSG DNAVNPERSK PSDLASTYTV LATFPSISAA
QNALKKQINS VNKFKLRTSK KHYDFHILER ASSQ
//
